Basic Information:

  VIRBase ID:  

VHID00335497

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART11-5p:  MIMAT0003421          RNF8:  NR_046399     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART11-5p	RNF8
miRBase Accession/Entrez ID	MIMAT0003421	9025
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	hRNF8

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNF8	chr6:37354740(+) A-I      intronic chr6:37340690(+) A-I      intronic chr6:37340695(+) A-I      intronic chr6:37341283(+) A-I      intronic chr6:37341319(+) A-I      intronic chr6:37341374(+) A-I      intronic chr6:37341384(+) A-I      intronic chr6:37341404(+) A-I      intronic chr6:37345036(+) A-I      intronic chr6:37345053(+) A-I      intronic chr6:37341247(+) A-I      intronic chr6:37340491(+) A-I      intronic chr6:37345100(+) A-I      intronic chr6:37345896(+) A-I      intronic chr6:37345909(+) A-I      intronic chr6:37345067(+) A-I      intronic chr6:37345806(+) A-I      intronic chr6:37345855(+) A-I      intronic chr6:37345884(+) A-I      intronic chr6:37348649(+) A-I      intronic chr6:37353355(+) A-I      intronic chr6:37356605(+) A-I      intronic chr6:37356621(+) A-I      intronic chr6:37345910(+) A-I      intronic chr6:37346143(+) A-I      intronic chr6:37346175(+) A-I      intronic chr6:37346206(+) A-I      intronic chr6:37346218(+) A-I      intronic chr6:37346219(+) A-I      intronic chr6:37346224(+) A-I      intronic chr6:37346266(+) A-I      intronic chr6:37346297(+) A-I      intronic chr6:37346334(+) A-I      intronic chr6:37346816(+) A-I      intronic chr6:37347807(+) A-I      intronic chr6:37348259(+) A-I      intronic chr6:37348367(+) A-I      intronic chr6:37348372(+) A-I      intronic chr6:37345955(+) A-I      intronic chr6:37353886(+) A-I      intronic chr6:37356611(+) A-I      intronic chr6:37355292(+) A-I      intronic chr6:37355283(+) A-I      intronic chr6:37348739(+) A-I      intronic chr6:37353323(+) A-I      intronic chr6:37353309(+) A-I      intronic chr6:37353653(+) A-I      intronic chr6:37353276(+) A-I      intronic chr6:37348735(+) A-I      intronic chr6:37345087(+) A-I      intronic chr6:37345105(+) A-I      intronic chr6:37345115(+) A-I      intronic chr6:37326722(+) A-I      intronic chr6:37348702(+) A-I      intronic chr6:37348681(+) A-I      intronic chr6:37348668(+) A-I      intronic chr6:37348545(+) A-I      intronic chr6:37326726(+) A-I      intronic chr6:37340624(+) A-I      intronic chr6:37353216(+) A-I      intronic chr6:37352963(+) A-I      intronic chr6:37352935(+) A-I      intronic chr6:37352929(+) A-I      intronic chr6:37352919(+) A-I      intronic chr6:37340625(+) A-I      intronic chr6:37350706(+) A-I      intronic chr6:37350699(+) A-I      intronic chr6:37350627(+) A-I      intronic chr6:37340666(+) A-I      intronic chr6:37345129(+) A-I      intronic chr6:37340657(+) A-I      intronic chr6:37353880(+) A-I      intronic chr6:37340725(+) A-I      intronic chr6:37352056(+) A-I      intronic chr6:37353654(+) A-I      intronic chr6:37355340(+) A-I      intronic chr6:37346176(+) A-I      intronic chr6:37347945(+) A-I      intronic chr6:37345874(+) A-I      intronic chr6:37344993(+) A-I      intronic chr6:37346168(+) A-I      intronic chr6:37346225(+) A-I      intronic chr6:37347966(+) A-I      intronic chr6:37355186(+) A-I      intronic chr6:37353050(+) A-I      intronic chr6:37353827(+) A-I      intronic chr6:37347802(+) A-I      intronic chr6:37348679(+) A-I      intronic chr6:37345923(+) A-I      intronic chr6:37348539(+) A-I      intronic chr6:37345027(+) A-I      intronic chr6:37346221(+) A-I      intronic chr6:37345127(+) A-I      intronic chr6:37356449(+) A-I      intronic chr6:37356533(+) A-I      intronic chr6:37326609(+) A-I      intronic chr6:37326611(+) A-I      intronic chr6:37347783(+) A-I      intronic chr6:37356602(+) A-I      intronic chr6:37356473(+) A-I      intronic chr6:37348392(+) A-I      intronic chr6:37355256(+) A-I      intronic chr6:37346857(+) A-I      intronic chr6:37353217(+) A-I      intronic chr6:37345033(+) A-I      intronic chr6:37341295(+) A-I      intronic chr6:37346009(+) A-I      intronic chr6:37348639(+) A-I      intronic chr6:37356634(+) A-I      intronic chr6:37351980(+) A-I      intronic chr6:37353193(+) A-I      intronic chr6:37353051(+) A-I      intronic chr6:37347713(+) A-I      intronic chr6:37346256(+) A-I      intronic chr6:37345949(+) A-I      intronic chr6:37353063(+) A-I      intronic chr6:37348642(+) A-I      intronic chr6:37344879(+) A-I      intronic chr6:37356630(+) A-I      intronic chr6:37352932(+) A-I      intronic chr6:37346162(+) A-I      intronic chr6:37348588(+) A-I      intronic chr6:37347876(+) A-I      intronic chr6:37355178(+) A-I      intronic chr6:37356465(+) A-I      intronic chr6:37355246(+) A-I      intronic chr6:37346121(+) A-I      intronic chr6:37356653(+) A-I      intronic chr6:37346057(+) A-I      intronic chr6:37341427(+) A-I      intronic chr6:37352890(+) A-I      intronic chr6:37353213(+) A-I      intronic chr6:37356598(+) A-I      intronic chr6:37348656(+) A-I      intronic chr6:37347882(+) A-I      intronic chr6:37348559(+) A-I      intronic chr6:37355243(+) A-I      intronic chr6:37353353(+) A-I      intronic chr6:37345842(+) A-I      intronic chr6:37347721(+) A-I      intronic chr6:37350602(+) A-I      intronic chr6:37353148(+) A-I      intronic chr6:37352867(+) A-I      intronic chr6:37347776(+) A-I      intronic chr6:37346929(+) A-I      intronic chr6:37356501(+) A-I      intronic chr6:37350643(+) A-I      intronic chr6:37353149(+) A-I      intronic chr6:37344949(+) A-I      intronic chr6:37346856(+) A-I      intronic chr6:37352050(+) A-I      intronic chr6:37356505(+) A-I      intronic chr6:37347819(+) A-I      intronic chr6:37341206(+) A-I      intronic chr6:37350661(+) A-I      intronic chr6:37348598(+) A-I      intronic chr6:37353424(+) A-I      intronic chr6:37352846(+) A-I      intronic chr6:37355218(+) A-I      intronic chr6:37352915(+) A-I      intronic chr6:37352046(+) A-I      intronic chr6:37347913(+) A-I      intronic chr6:37347893(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RNF8	chr6:37341206(+) A-G intron -    22484847 chr6:37345808(+) A-G intron -    22484847 chr6:37346298(+) A-G intron -    22484847 chr6:37346856(+) A-G intron -    22484847 chr6:37346857(+) A-G intron -    22484847 chr6:37347713(+) A-G intron -    22484847 chr6:37347721(+) A-G intron -    22484847 chr6:37347776(+) A-G intron -    22484847 chr6:37348559(+) A-G intron -    22484847 chr6:37348563(+) A-G intron -    22484847 chr6:37348576(+) A-G intron -    22484847 chr6:37348659(+) A-G intron -    22484847 chr6:37348679(+) A-G intron -    22484847 chr6:37350633(+) A-G intron -    22484847 chr6:37352867(+) A-G intron -    22484847 chr6:37352915(+) A-G intron -    22484847 chr6:37352932(+) A-G intron -    22484847 chr6:37353193(+) A-G intron -    22484847 chr6:37353344(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNF8	chr6:37321888-37321889(+) m6A 5'UTR//exon       24284625 chr6:37321971-37321972(+) m6A CDS//exon//intron       24209618//22575960 chr6:37326969-37326970(+) m6A CDS//intron       24209618 chr6:37326974-37326975(+) m6A CDS//intron       24209618 chr6:37336281-37336282(+) m6A 3'UTR//CDS//exon       24284625//24981863//22608085 chr6:37336297-37336298(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336329-37336330(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336401-37336402(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336409-37336410(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336472-37336473(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336661-37336662(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336731-37336732(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336816-37336817(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336847-37336848(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336860-37336861(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336891-37336892(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336899-37336900(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085 chr6:37336964-37336965(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37336981-37336982(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr6:37337581-37337582(+) m6A exon//intron       24284625//24209618//24981863//22608085 chr6:37337620-37337621(+) m6A exon//intron       24981863//22608085 chr6:37339315-37339316(+) m6A 3'UTR//CDS       24209618 chr6:37342435-37342436(+) m6A 3'UTR//CDS//intron       24209618//24981863 chr6:37342462-37342463(+) m6A 3'UTR//CDS//intron       24981863 chr6:37342479-37342480(+) m6A 3'UTR//CDS//intron       24981863 chr6:37349016-37349017(+) m6A 3'UTR//CDS//intron       24981863//22608085 chr6:37349049-37349050(+) m6A 3'UTR//CDS//intron       24284625//24981863//22608085 chr6:37358536-37358537(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr6:37358561-37358562(+) m6A 3'UTR//CDS       24284625//25456834//24981863//22608085 chr6:37358652-37358653(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr6:37358658-37358659(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr6:37358774-37358775(+) m6A 3'UTR       24284625//25456834 chr6:37359130-37359131(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BART11-5p	Exosome B cell line (Raji)     21505438
	RNF8	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART11-5p
Interactor2: RNF8

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg