Detail Information

Basic Information:


  VIRBase ID:  

VHID00326669

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART8-3p:           GXYLT1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART8-3p GXYLT1
miRBase
Accession/Entrez ID		 MIMAT0003418 283464
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - GLT8D3

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR GXYLT1
chr12:42479906(-) A-I      3'UTR
chr12:42479886(-) A-I      3'UTR
chr12:42479896(-) A-I      3'UTR
chr12:42479871(-) A-I      3'UTR
chr12:42481095(-) A-I      3'UTR
chr12:42479925(-) A-I      3'UTR
chr12:42479918(-) A-I      3'UTR
chr12:42481096(-) A-I      3'UTR
chr12:42486611(-) A-I      intronic
chr12:42479913(-) A-I      3'UTR
chr12:42481058(-) A-I      3'UTR
chr12:42481059(-) A-I      3'UTR
chr12:42479867(-) A-I      3'UTR
chr12:42479866(-) A-I      3'UTR
chr12:42532993(-) A-I      intronic
chr12:42520600(-) A-I      intronic
chr12:42520638(-) A-I      intronic
chr12:42520674(-) A-I      intronic
chr12:42528206(-) A-I      intronic
chr12:42528211(-) A-I      intronic
chr12:42528217(-) A-I      intronic
chr12:42486996(-) A-I      intronic
chr12:42530745(-) A-I      intronic
chr12:42530805(-) A-I      intronic
chr12:42531987(-) A-I      intronic
chr12:42520599(-) A-I      intronic
chr12:42532973(-) A-I      intronic
chr12:42532986(-) A-I      intronic
chr12:42501258(-) A-I      intronic
chr12:42487028(-) A-I      intronic
chr12:42487037(-) A-I      intronic
chr12:42487073(-) A-I      intronic
chr12:42488201(-) A-I      intronic
chr12:42501321(-) A-I      intronic
chr12:42514537(-) A-I      intronic
chr12:42515216(-) A-I      intronic
chr12:42515317(-) A-I      intronic
chr12:42519658(-) A-I      intronic
chr12:42520171(-) A-I      intronic
chr12:42493596(-) A-I      intronic
chr12:42536303(-) A-I      intronic
chr12:42519973(-) A-I      intronic
chr12:42487127(-) A-I      intronic
chr12:42531969(-) A-I      intronic
chr12:42530668(-) A-I      intronic
chr12:42501371(-) A-I      intronic
chr12:42520492(-) A-I      intronic
chr12:42520158(-) A-I      intronic
chr12:42497027(-) A-I      intronic
chr12:42519972(-) A-I      intronic
chr12:42520136(-) A-I      intronic
chr12:42515289(-) A-I      intronic
chr12:42487990(-) A-I      intronic
chr12:42514588(-) A-I      intronic
chr12:42531496(-) A-I      intronic
chr12:42488378(-) A-I      intronic
chr12:42487010(-) A-I      intronic
chr12:42519599(-) A-I      intronic
chr12:42530652(-) A-I      intronic
chr12:42520127(-) A-I      intronic
chr12:42527919(-) A-I      intronic
chr12:42500644(-) A-I      intronic
chr12:42530673(-) A-I      intronic
chr12:42519936(-) A-I      intronic
chr12:42487121(-) A-I      intronic
chr12:42488349(-) A-I      intronic
chr12:42527890(-) A-I      intronic
chr12:42514556(-) A-I      intronic
chr12:42532009(-) A-I      intronic
chr12:42519657(-) A-I      intronic
chr12:42488317(-) A-I      intronic
chr12:42515246(-) A-I      intronic
chr12:42515231(-) A-I      intronic
chr12:42531957(-) A-I      intronic
chr12:42487959(-) A-I      intronic
chr12:42530825(-) A-I      intronic
chr12:42536369(-) A-I      intronic
chr12:42487619(-) A-I      intronic
chr12:42487562(-) A-I      intronic
chr12:42528312(-) A-I      intronic
chr12:42532964(-) A-I      intronic
chr12:42527949(-) A-I      intronic
chr12:42531929(-) A-I      intronic
chr12:42536276(-) A-I      intronic
chr12:42501327(-) A-I      intronic
chr12:42536217(-) A-I      intronic
chr12:42536432(-) A-I      intronic
chr12:42500672(-) A-I      intronic
chr12:42514465(-) A-I      intronic
chr12:42488366(-) A-I      intronic
chr12:42487511(-) A-I      intronic
chr12:42530651(-) A-I      intronic
chr12:42476490(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED GXYLT1
chr12:42488349(-) A-G intron -    22484847
chr12:42476490(-) A-G exon 3'UTR    22484847
chr12:42500672(-) A-G intron -    22484847
chr12:42514465(-) A-G intron -    22484847
chr12:42515231(-) A-G intron -    22484847
chr12:42519657(-) A-G intron -    22484847
chr12:42520127(-) A-G intron -    22484847
chr12:42520136(-) A-G intron -    22484847
chr12:42520158(-) A-G intron -    22484847
chr12:42520492(-) A-G intron -    22484847
chr12:42530651(-) A-G intron -    22484847
chr12:42530652(-) A-G intron -    22484847
chr12:42530668(-) A-G intron -    22484847
chr12:42530673(-) A-G intron -    22484847
chr12:42531957(-) A-G intron -    22484847
chr12:42531969(-) A-G intron -    22484847
chr12:42532009(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase GXYLT1
chr12:42477341-42477342(-) m6A 3'UTR       27773535
chr12:42477366-42477367(-) m6A 3'UTR       27773535
chr12:42477643-42477644(-) m6A 3'UTR       27773535
chr12:42477684-42477685(-) m6A 3'UTR       27773535
chr12:42477692-42477693(-) m6A 3'UTR       27773535
chr12:42477979-42477980(-) m6A 3'UTR       24981863//27773535//22608085
chr12:42480958-42480959(-) m6A 3'UTR       24981863//27773535
chr12:42481146-42481147(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr12:42481228-42481229(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr12:42481246-42481247(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr12:42481309-42481310(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr12:42481395-42481396(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr12:42481419-42481420(-) Y 3'UTR       26075521
chr12:42481554-42481555(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr12:42481641-42481642(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr12:42481685-42481686(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr12:42481695-42481696(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr12:42481701-42481702(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr12:42481710-42481711(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr12:42491307-42491308(-) m6A CDS       24284625//24981863//27773535//22608085
chr12:42538353-42538354(-) m1A CDS       26863196//26863410
chr12:42538544-42538545(-) m6A 5'UTR       24209618//25456834//24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate GXYLT1
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART8-3p
Interactor2: GXYLT1

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//PITA//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22100165 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line BC-1 cells Interactor2 expression Downregulation
Description Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites.Clusters with seed matches to expressed miRNAs were considered candidate target sites. Of the clusters mapping to human 3'UTRs, 69% (BC-1) and 70% (BC-3) had seed matches to expressed miRNAs (Tables S6).Table S6A BC-1 derived 3'UTR clusters with seed matches to expressed miRNAs.

Starting a new search, please wait ...