Basic Information:

  VIRBase ID:  

VHID00312314

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART5-5p:  MIMAT0003413          SPRYD4:  NM_207344     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART5-5p	SPRYD4
miRBase Accession/Entrez ID	MIMAT0003413	283377
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SPRYD4	chr12:56864318(+) A-I      3'UTR chr12:56864371(+) A-I      3'UTR chr12:56864209(+) A-I      3'UTR chr12:56864311(+) A-I      3'UTR chr12:56864370(+) A-I      3'UTR chr12:56864208(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SPRYD4	chr12:56864208(+) A-G intron -    22484847 chr12:56864209(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SPRYD4	chr12:56862835-56862836(+) m6A 5'UTR//CDS       24284625//24981863//22608085 chr12:56862848-56862849(+) m6A 5'UTR//CDS       24284625//24981863//22608085 chr12:56862975-56862976(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:56862997-56862998(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:56863059-56863060(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:56863268-56863269(+) m6A 5'UTR//CDS       24284625//25456834//24981863 chr12:56863541-56863542(+) m6A 3'UTR//5'UTR       24284625//24981863 chr12:56863656-56863657(+) m6A 3'UTR//CDS       24284625//24981863 chr12:56872891-56872892(+) m6A 3'UTR       - chr12:56872915-56872916(+) m6A 3'UTR       - chr12:56872976-56872977(+) m6A 3'UTR       - chr12:56873014-56873015(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SPRYD4	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART5-5p
Interactor2: SPRYD4

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg