Basic Information:

  VIRBase ID:  

VHID00308842

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART5-5p:  MIMAT0003413          PON2:  NM_000305     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART5-5p	PON2
miRBase Accession/Entrez ID	MIMAT0003413	5445
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PON2	chr7:95059883(-) A-I      intronic chr7:95060022(-) A-I      intronic chr7:95062615(-) A-I      intronic chr7:95062616(-) A-I      intronic chr7:95063503(-) A-I      intronic chr7:95062661(-) A-I      intronic chr7:95062626(-) A-I      intronic chr7:95063548(-) A-I      intronic chr7:95062657(-) A-I      intronic chr7:95063547(-) A-I      intronic chr7:95063584(-) A-I      intronic chr7:95063543(-) A-I      intronic chr7:95059989(-) A-I      intronic chr7:95059950(-) A-I      intronic chr7:95061550(-) A-I      intronic chr7:95059990(-) A-I      intronic chr7:95061525(-) A-I      intronic chr7:95059884(-) A-I      intronic chr7:95062632(-) A-I      intronic chr7:95063440(-) A-I      intronic chr7:95063464(-) A-I      intronic chr7:95060869(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PON2	chr7:95059989(-) A-G intron -    22484847 chr7:95059990(-) A-G intron -    22484847 chr7:95060031(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PON2	chr7:95034188-95034189(-) m6A 3'UTR       27773535 chr7:95034262-95034263(-) m6A 3'UTR       27773535 chr7:95034352-95034353(-) m6A 3'UTR       24284625//26404942//27773535 chr7:95034432-95034433(-) m6A 3'UTR       24981863//26404942//27773535 chr7:95034460-95034461(-) m6A 3'UTR       26404942//27773535 chr7:95034647-95034648(-) m6A 3'UTR//CDS       24981863//26404942 chr7:95034699-95034700(-) Am 3'UTR//CDS       - chr7:95034783-95034784(-) m6A 3'UTR//CDS       26404942 chr7:95036328-95036329(-) m6A 3'UTR//CDS       26404942 chr7:95039314-95039315(-) m6A 3'UTR//CDS//exon       26404942 chr7:95039324-95039325(-) m6A 3'UTR//CDS//exon       26404942 chr7:95039388-95039389(-) m6A 3'UTR//CDS//exon       26404942 chr7:95041063-95041064(-) m6A 3'UTR//CDS//intron       26404942 chr7:95041628-95041629(-) m6A 3'UTR//CDS       26404942 chr7:95041708-95041709(-) m6A 3'UTR//CDS       26404942 chr7:95041771-95041772(-) m6A 3'UTR//5'UTR//CDS       26404942 chr7:95042220-95042221(-) m6A exon//intron       24981863//27773535 chr7:95042239-95042240(-) m6A exon//intron       24981863//27773535 chr7:95042255-95042256(-) m6A exon//intron       24981863//27773535 chr7:95042262-95042263(-) m6A exon//intron       24981863//27773535 chr7:95053858-95053859(-) m6A 5'UTR//CDS//exon//intron       26404942 chr7:95063611-95063612(-) m6A 5'UTR//intron       24981863//27773536//22575960 chr7:95063620-95063621(-) m6A 5'UTR//intron       24981863//27773536//22575960 chr7:95064381-95064382(-) m6A 5'UTR       24981863//26404942//27773536 chr7:95064427-95064428(-) m6A 5'UTR       24981863 chr7:95064433-95064434(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PON2	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART5-5p
Interactor2: PON2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg