Basic Information:

  VIRBase ID:  

VHID00308457

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART5-5p:  MIMAT0003413          HMMR:  NM_001142556     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART5-5p	HMMR
miRBase Accession/Entrez ID	MIMAT0003413	3161
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CD168//IHABP//RHAMM

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HMMR	chr5:162906594(+) A-I      intronic chr5:162906626(+) A-I      intronic chr5:162906656(+) A-I      intronic chr5:162914006(+) A-I      intronic chr5:162906589(+) A-I      intronic chr5:162893193(+) A-I      intronic chr5:162906415(+) A-I      intronic chr5:162891531(+) A-I      intronic chr5:162892470(+) A-I      intronic chr5:162892846(+) A-I      intronic chr5:162906498(+) A-I      intronic chr5:162892735(+) A-I      intronic chr5:162892856(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	HMMR	chr5:162892470(+) A-G intron -    22484847 chr5:162892735(+) A-G intron -    22484847 chr5:162906498(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HMMR	chr5:162887251-162887252(+) m6A 5'UTR       22608085 chr5:162887282-162887283(+) m6A 5'UTR       24981863//22608085 chr5:162887290-162887291(+) m6A 5'UTR       24981863//22608085 chr5:162887301-162887302(+) m6A 5'UTR       24981863//22608085 chr5:162887316-162887317(+) m6A 5'UTR       24981863//22608085 chr5:162887621-162887622(+) m6A 5'UTR//intron       24981863 chr5:162890896-162890897(+) m6A 5'UTR//CDS//exon//intron       24981863 chr5:162890916-162890917(+) m6A 5'UTR//CDS//exon//intron       24981863 chr5:162896680-162896681(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr5:162896703-162896704(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr5:162896715-162896716(+) Am 5'UTR//CDS//exon       - chr5:162896754-162896755(+) m6A CDS//exon       24284625//24981863//22608085 chr5:162896789-162896790(+) m6A CDS//exon       24284625//24981863//27773535//22608085 chr5:162896811-162896812(+) m6A CDS//exon       24284625//24981863//27773535//22608085 chr5:162896819-162896820(+) m6A CDS//exon       24981863//27773535//22608085 chr5:162896878-162896879(+) m6A exon//intron       24981863//27773535//22608085 chr5:162898246-162898247(+) m6A CDS       24981863//22608085 chr5:162898254-162898255(+) m6A CDS       24981863//22608085 chr5:162898265-162898266(+) m6A CDS       24981863//22608085 chr5:162898466-162898467(+) m6A CDS       24981863//27773535 chr5:162900224-162900225(+) m6A CDS       24981863//27773535 chr5:162900232-162900233(+) m6A CDS       24981863//27773535 chr5:162900422-162900423(+) Y CDS       26075521 chr5:162901065-162901066(+) m6A CDS       24981863 chr5:162901087-162901088(+) m6A CDS       24981863 chr5:162901119-162901120(+) m6A CDS       24981863 chr5:162901126-162901127(+) m6A CDS       24981863 chr5:162901144-162901145(+) m6A CDS       24981863 chr5:162902553-162902554(+) m6A CDS       24981863//27773535 chr5:162902591-162902592(+) m6A CDS       24981863//27773535 chr5:162902654-162902655(+) m6A CDS       24981863//27773535 chr5:162905701-162905702(+) m6A CDS       24981863//27773535 chr5:162909694-162909695(+) m6A CDS       24981863 chr5:162910044-162910045(+) m6A CDS       27773535 chr5:162910065-162910066(+) m6A CDS       27773535 chr5:162910120-162910121(+) m6A CDS       24981863//27773535 chr5:162910144-162910145(+) m6A CDS       24981863//27773535 chr5:162910154-162910155(+) m6A CDS       24981863//27773535 chr5:162910168-162910169(+) Am CDS       - chr5:162910345-162910346(+) m6A CDS       24981863//27773535 chr5:162910358-162910359(+) m6A CDS       24981863//27773535 chr5:162910363-162910364(+) m6A CDS       24981863//27773535 chr5:162911103-162911104(+) m6A CDS       24981863//27773535 chr5:162911121-162911122(+) m6A CDS       27773535 chr5:162911139-162911140(+) m6A CDS       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HMMR	Centrosome Cells (HeLa-Kyoto|HeLa)     33649340 Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART5-5p
Interactor2: HMMR

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg