Detail Information

Basic Information:


  VIRBase ID:  

VHID00304804

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART4-5p:           STOM:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART4-5p STOM
miRBase
Accession/Entrez ID		 MIMAT0003412 2040
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - BND7//EPB7//EPB72

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR STOM
chr9:124120630(-) A-I      intronic
chr9:124120620(-) A-I      intronic
chr9:124120719(-) A-I      intronic
chr9:124120462(-) A-I      intronic
chr9:124119214(-) A-I      intronic
chr9:124120382(-) A-I      intronic
chr9:124120376(-) A-I      intronic
chr9:124119919(-) A-I      intronic
chr9:124119198(-) A-I      intronic
chr9:124119818(-) A-I      intronic
chr9:124119910(-) A-I      intronic
chr9:124120386(-) A-I      intronic
chr9:124102852(-) A-I      3'UTR
chr9:124102879(-) A-I      3'UTR
chr9:124102849(-) A-I      3'UTR
chr9:124102818(-) A-I      3'UTR
chr9:124102898(-) A-I      3'UTR
chr9:124102916(-) A-I      3'UTR
chr9:124102946(-) A-I      3'UTR
chr9:124102945(-) A-I      3'UTR
chr9:124102928(-) A-I      3'UTR
chr9:124119988(-) A-I      intronic
chr9:124120656(-) A-I      intronic
chr9:124108406(-) A-I      intronic
chr9:124102906(-) A-I      3'UTR
chr9:124104500(-) A-I      intronic
chr9:124120322(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase STOM
chr9:124102564-124102565(-) m6A 3'UTR//intron       26404942
chr9:124102597-124102598(-) m6A 3'UTR//intron       26404942
chr9:124102616-124102617(-) m6A 3'UTR//intron       26404942
chr9:124103160-124103161(-) m6A 3'UTR//intron       26404942
chr9:124103438-124103439(-) m6A 3'UTR//intron       26404942
chr9:124103497-124103498(-) m6A CDS//intron       26404942//27773535//22575960
chr9:124103555-124103556(-) m6A CDS//intron       26404942//27773535//22575960
chr9:124103583-124103584(-) m6A CDS//intron       26404942//27773535//22575960
chr9:124110358-124110359(-) m6A CDS//intron       26404942//22575960
chr9:124118411-124118412(-) m6A CDS       27371828//27773536
chr9:124128422-124128423(-) m6A intron       24284625//27371828//27773536
chr9:124128432-124128433(-) m6A intron       24284625//27371828//27773536
chr9:124128441-124128442(-) m6A intron       24284625//27371828//27773536
chr9:124128514-124128515(-) m6A intron       24284625//25456834//24981863//27371828//27773536
chr9:124128520-124128521(-) m6A intron       24284625//25456834//24981863//27371828//27773536
chr9:124132439-124132440(-) m6A CDS       24284625//25456834//24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate STOM
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol HCC cell line (HepG2)     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART4-5p
Interactor2: STOM

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//PITA//Targetscan
Support Database ViRBase//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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