Detail Information

Basic Information:


  VIRBase ID:  

VHID00304156

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART3-3p:           ITPRIPL2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART3-3p ITPRIPL2
miRBase
Accession/Entrez ID		 MIMAT0003411 162073
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ITPRIPL2
chr16:19131838(+) A-I      3'UTR
chr16:19131687(+) A-I      3'UTR
chr16:19131581(+) A-I      3'UTR
chr16:19131678(+) A-I      3'UTR
chr16:19131664(+) A-I      3'UTR
chr16:19131638(+) A-I      3'UTR
chr16:19131626(+) A-I      3'UTR
chr16:19131900(+) A-I      3'UTR
chr16:19131888(+) A-I      3'UTR
chr16:19129540(+) A-I      3'UTR
chr16:19129737(+) A-I      3'UTR
chr16:19129799(+) A-I      3'UTR
chr16:19131483(+) A-I      3'UTR
chr16:19129689(+) A-I      3'UTR
chr16:19131613(+) A-I      3'UTR
chr16:19131503(+) A-I      3'UTR
chr16:19131694(+) A-I      3'UTR
chr16:19129595(+) A-I      3'UTR
chr16:19131966(+) A-I      3'UTR
chr16:19129702(+) A-I      3'UTR
chr16:19131986(+) A-I      3'UTR
chr16:19129721(+) A-I      3'UTR
chr16:19129728(+) A-I      3'UTR
chr16:19131504(+) A-I      3'UTR
chr16:19129584(+) A-I      3'UTR
chr16:19131593(+) A-I      3'UTR
chr16:19129708(+) A-I      3'UTR
chr16:19131995(+) A-I      3'UTR
chr16:19132008(+) A-I      3'UTR
chr16:19131529(+) A-I      3'UTR
chr16:19131643(+) A-I      3'UTR
chr16:19132060(+) A-I      3'UTR
chr16:19129730(+) A-I      3'UTR
chr16:19131665(+) A-I      3'UTR
chr16:19131666(+) A-I      3'UTR
chr16:19129688(+) A-I      3'UTR
chr16:19129604(+) A-I      3'UTR
chr16:19131639(+) A-I      3'UTR
chr16:19132020(+) A-I      3'UTR
chr16:19131543(+) A-I      3'UTR
chr16:19129667(+) A-I      3'UTR
chr16:19131604(+) A-I      3'UTR
chr16:19129736(+) A-I      3'UTR
chr16:19131427(+) A-I      3'UTR
chr16:19131876(+) A-I      3'UTR
chr16:19129553(+) A-I      3'UTR
chr16:19131904(+) A-I      3'UTR
chr16:19131781(+) A-I      3'UTR
chr16:19131852(+) A-I      3'UTR
chr16:19129683(+) A-I      3'UTR
chr16:19129699(+) A-I      3'UTR
chr16:19129640(+) A-I      3'UTR
chr16:19131885(+) A-I      3'UTR
chr16:19131898(+) A-I      3'UTR
chr16:19131545(+) A-I      3'UTR
chr16:19129531(+) A-I      3'UTR
chr16:19129532(+) A-I      3'UTR
chr16:19129666(+) A-I      3'UTR
chr16:19131833(+) A-I      3'UTR
chr16:19131587(+) A-I      3'UTR
chr16:19132048(+) A-I      3'UTR
chr16:19129523(+) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ITPRIPL2
chr16:19125318-19125319(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr16:19125376-19125377(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr16:19125527-19125528(+) m6A intron       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr16:19125597-19125598(+) m6A intron       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr16:19125684-19125685(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19126052-19126053(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr16:19126246-19126247(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19126465-19126466(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19126472-19126473(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19126634-19126635(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr16:19126831-19126832(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19126954-19126955(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19127007-19127008(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19127110-19127111(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19127252-19127253(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr16:19127384-19127385(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr16:19127391-19127392(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr16:19127604-19127605(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127615-19127616(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127629-19127630(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127717-19127718(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127754-19127755(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127785-19127786(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127790-19127791(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19127795-19127796(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19129609-19129610(+) m6A 3'UTR       24209618
chr16:19130078-19130079(+) m6A 3'UTR       24981863
chr16:19130117-19130118(+) m6A 3'UTR       24981863
chr16:19130123-19130124(+) m6A 3'UTR       24981863
chr16:19130184-19130185(+) m6A 3'UTR       24981863
chr16:19130408-19130409(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:19130495-19130496(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:19130527-19130528(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:19130545-19130546(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:19130560-19130561(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:19130644-19130645(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19130681-19130682(+) m6A 3'UTR       24284625//24981863//22608085
chr16:19130699-19130700(+) m6A 3'UTR       24981863//22608085
chr16:19132502-19132503(+) m6A 3'UTR       24981863
chr16:19132631-19132632(+) m6A 3'UTR       24284625
chr16:19132677-19132678(+) m6A 3'UTR       24284625
chr16:19132741-19132742(+) m6A 3'UTR       24284625
chr16:19132835-19132836(+) m6A 3'UTR       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ITPRIPL2
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART3-3p
Interactor2: ITPRIPL2

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//PITA//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

Starting a new search, please wait ...