Basic Information:

  VIRBase ID:  

VHID00303891

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6055

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART3-3p:  MIMAT0003411          KTI12:  NM_138417     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART3-3p	KTI12
miRBase Accession/Entrez ID	MIMAT0003411	112970
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SBBI81//TOT4

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KTI12	chr1:52497846-52497847(-) m6A 3'UTR       24981863//27773535//22608085 chr1:52497888-52497889(-) m6A 3'UTR       24209618//24981863//27773535//22608085 chr1:52497989-52497990(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:52497995-52497996(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:52498005-52498006(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:52498031-52498032(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:52498116-52498117(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:52498131-52498132(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:52498166-52498167(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:52498183-52498184(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:52498234-52498235(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:52498423-52498424(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr1:52498482-52498483(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr1:52498546-52498547(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr1:52498609-52498610(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085 chr1:52498681-52498682(-) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr1:52498756-52498757(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr1:52498812-52498813(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr1:52498914-52498915(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr1:52498957-52498958(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr1:52498971-52498972(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr1:52499059-52499060(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr1:52499085-52499086(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr1:52499197-52499198(-) m6A CDS       24284625//24981863//27371828//27773536 chr1:52499299-52499300(-) m6A CDS       24284625//27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	KTI12	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART3-3p
Interactor2: KTI12

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//PITA//Targetscan
Support Database	RepTar//ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	Downregulation
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).