Basic Information:

  VIRBase ID:  

VHID00302279

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6055

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART3-3p:  MIMAT0003411          SH3PXD2A:  NM_014631     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART3-3p	SH3PXD2A
miRBase Accession/Entrez ID	MIMAT0003411	9644
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	FISH//SH3MD1//TKS5

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SH3PXD2A	chr10:105530448(-) A-I      intronic chr10:105503212(-) A-I      intronic chr10:105448904(-) A-I      intronic chr10:105448859(-) A-I      intronic chr10:105448832(-) A-I      intronic chr10:105448814(-) A-I      intronic chr10:105537979(-) A-I      intronic chr10:105522067(-) A-I      intronic chr10:105531410(-) A-I      intronic chr10:105359530(-) A-I      3'UTR chr10:105416422(-) A-I      intronic chr10:105449340(-) A-I      intronic chr10:105501871(-) A-I      intronic chr10:105448864(-) A-I      intronic chr10:105359538(-) A-I      3'UTR chr10:105531431(-) A-I      intronic chr10:105359560(-) A-I      3'UTR chr10:105359511(-) A-I      3'UTR chr10:105520607(-) A-I      intronic chr10:105532791(-) A-I      intronic chr10:105520082(-) A-I      intronic chr10:105533392(-) A-I      intronic chr10:105359556(-) A-I      3'UTR chr10:105607006(-) A-I      intronic chr10:105520070(-) A-I      intronic chr10:105607640(-) A-I      intronic chr10:105535941(-) A-I      intronic chr10:105359517(-) A-I      3'UTR chr10:105359520(-) A-I      3'UTR chr10:105359528(-) A-I      3'UTR chr10:105535902(-) A-I      intronic chr10:105448913(-) A-I      intronic chr10:105439840(-) A-I      intronic chr10:105444615(-) A-I      intronic chr10:105442334(-) A-I      intronic chr10:105444766(-) A-I      intronic chr10:105446553(-) A-I      intronic chr10:105446568(-) A-I      intronic chr10:105446752(-) A-I      intronic chr10:105448779(-) A-I      intronic chr10:105448789(-) A-I      intronic chr10:105555991(-) A-I      intronic chr10:105449301(-) A-I      intronic chr10:105440212(-) A-I      intronic chr10:105448811(-) A-I      intronic chr10:105449179(-) A-I      intronic chr10:105449188(-) A-I      intronic chr10:105513146(-) A-I      intronic chr10:105521999(-) A-I      intronic chr10:105533354(-) A-I      intronic chr10:105533372(-) A-I      intronic chr10:105533378(-) A-I      intronic chr10:105533466(-) A-I      intronic chr10:105535924(-) A-I      intronic chr10:105573110(-) A-I      intronic chr10:105441612(-) A-I      intronic chr10:105591398(-) A-I      intronic chr10:105531299(-) A-I      intronic chr10:105607001(-) A-I      intronic chr10:105442428(-) A-I      intronic chr10:105442429(-) A-I      intronic chr10:105442339(-) A-I      intronic chr10:105441671(-) A-I      intronic chr10:105607635(-) A-I      intronic chr10:105443231(-) A-I      intronic chr10:105442900(-) A-I      intronic chr10:105442874(-) A-I      intronic chr10:105577294(-) A-I      intronic chr10:105442271(-) A-I      intronic chr10:105441402(-) A-I      intronic chr10:105416504(-) A-I      intronic chr10:105433065(-) A-I      intronic chr10:105439969(-) A-I      intronic chr10:105446642(-) A-I      intronic chr10:105439930(-) A-I      intronic chr10:105522002(-) A-I      intronic chr10:105555873(-) A-I      intronic chr10:105439876(-) A-I      intronic chr10:105521918(-) A-I      intronic chr10:105442357(-) A-I      intronic chr10:105439862(-) A-I      intronic chr10:105442366(-) A-I      intronic chr10:105439875(-) A-I      intronic chr10:105444985(-) A-I      intronic chr10:105529354(-) A-I      intronic chr10:105439911(-) A-I      intronic chr10:105477862(-) A-I      intronic chr10:105576834(-) A-I      intronic chr10:105449166(-) A-I      intronic chr10:105439739(-) A-I      intronic chr10:105444381(-) A-I      intronic chr10:105444294(-) A-I      intronic chr10:105444261(-) A-I      intronic chr10:105444228(-) A-I      intronic chr10:105444219(-) A-I      intronic chr10:105444214(-) A-I      intronic chr10:105443312(-) A-I      intronic chr10:105443172(-) A-I      intronic chr10:105443059(-) A-I      intronic chr10:105444683(-) A-I      intronic chr10:105443054(-) A-I      intronic chr10:105443014(-) A-I      intronic chr10:105442946(-) A-I      intronic chr10:105442873(-) A-I      intronic chr10:105442471(-) A-I      intronic chr10:105442439(-) A-I      intronic chr10:105368497(-) A-I      intronic chr10:105368514(-) A-I      intronic chr10:105415286(-) A-I      intronic chr10:105415409(-) A-I      intronic chr10:105416371(-) A-I      intronic chr10:105416385(-) A-I      intronic chr10:105444300(-) A-I      intronic chr10:105444696(-) A-I      intronic chr10:105444752(-) A-I      intronic chr10:105521963(-) A-I      intronic chr10:105416405(-) A-I      intronic chr10:105442393(-) A-I      intronic chr10:105441651(-) A-I      intronic chr10:105414448(-) A-I      intronic chr10:105442259(-) A-I      intronic chr10:105443221(-) A-I      intronic chr10:105442861(-) A-I      intronic chr10:105449260(-) A-I      intronic chr10:105530038(-) A-I      intronic chr10:105366105(-) A-I      intronic chr10:105444254(-) A-I      intronic chr10:105444621(-) A-I      intronic chr10:105439835(-) A-I      intronic chr10:105439919(-) A-I      intronic chr10:105536002(-) A-I      intronic chr10:105444695(-) A-I      intronic chr10:105440234(-) A-I      intronic chr10:105431831(-) A-I      intronic chr10:105533478(-) A-I      intronic chr10:105443320(-) A-I      intronic chr10:105434332(-) A-I      intronic chr10:105446669(-) A-I      intronic chr10:105431877(-) A-I      intronic chr10:105443254(-) A-I      intronic chr10:105530238(-) A-I      intronic chr10:105444569(-) A-I      intronic chr10:105576694(-) A-I      intronic chr10:105415348(-) A-I      intronic chr10:105444634(-) A-I      intronic chr10:105446778(-) A-I      intronic chr10:105444640(-) A-I      intronic chr10:105441461(-) A-I      intronic chr10:105445050(-) A-I      intronic chr10:105443020(-) A-I      intronic chr10:105433101(-) A-I      intronic chr10:105444382(-) A-I      intronic chr10:105440185(-) A-I      intronic chr10:105556785(-) A-I      intronic chr10:105443108(-) A-I      intronic chr10:105434329(-) A-I      intronic chr10:105442452(-) A-I      intronic chr10:105444939(-) A-I      intronic chr10:105444583(-) A-I      intronic chr10:105446643(-) A-I      intronic chr10:105441354(-) A-I      intronic chr10:105415338(-) A-I      intronic chr10:105535923(-) A-I      intronic chr10:105441419(-) A-I      intronic chr10:105444327(-) A-I      intronic chr10:105449311(-) A-I      intronic chr10:105448831(-) A-I      intronic chr10:105529327(-) A-I      intronic chr10:105482355(-) A-I      intronic chr10:105442351(-) A-I      intronic chr10:105521951(-) A-I      intronic chr10:105576827(-) A-I      intronic chr10:105446616(-) A-I      intronic chr10:105441571(-) A-I      intronic chr10:105431832(-) A-I      intronic chr10:105443215(-) A-I      intronic chr10:105441339(-) A-I      intronic chr10:105448741(-) A-I      intronic chr10:105440133(-) A-I      intronic chr10:105444774(-) A-I      intronic chr10:105467090(-) A-I      intronic chr10:105521934(-) A-I      intronic chr10:105444576(-) A-I      intronic chr10:105368498(-) A-I      intronic chr10:105501831(-) A-I      intronic chr10:105441336(-) A-I      intronic chr10:105414447(-) A-I      intronic chr10:105530000(-) A-I      intronic chr10:105444281(-) A-I      intronic chr10:105444604(-) A-I      intronic chr10:105433117(-) A-I      intronic chr10:105368475(-) A-I      intronic chr10:105444726(-) A-I      intronic chr10:105443160(-) A-I      intronic chr10:105444852(-) A-I      intronic chr10:105581921(-) A-I      intronic chr10:105449323(-) A-I      intronic chr10:105444953(-) A-I      intronic chr10:105555899(-) A-I      intronic chr10:105444692(-) A-I      intronic chr10:105577214(-) A-I      intronic chr10:105448828(-) A-I      intronic chr10:105442883(-) A-I      intronic chr10:105415347(-) A-I      intronic chr10:105414374(-) A-I      intronic chr10:105444656(-) A-I      intronic chr10:105444365(-) A-I      intronic chr10:105439902(-) A-I      intronic chr10:105443150(-) A-I      intronic chr10:105446702(-) A-I      intronic chr10:105443406(-) A-I      intronic chr10:105415312(-) A-I      intronic chr10:105443050(-) A-I      intronic chr10:105440023(-) A-I      intronic chr10:105533485(-) A-I      intronic chr10:105444297(-) A-I      intronic chr10:105556895(-) A-I      intronic chr10:105452783(-) A-I      intronic chr10:105441753(-) A-I      intronic chr10:105442949(-) A-I      intronic chr10:105433130(-) A-I      intronic chr10:105575392(-) A-I      intronic chr10:105442476(-) A-I      intronic chr10:105431469(-) A-I      intronic chr10:105447052(-) A-I      intronic chr10:105381535(-) A-I      intronic chr10:105442643(-) A-I      intronic chr10:105440124(-) A-I      intronic chr10:105530190(-) A-I      intronic chr10:105446897(-) A-I      intronic chr10:105442321(-) A-I      intronic chr10:105521964(-) A-I      intronic chr10:105382896(-) A-I      intronic chr10:105506428(-) A-I      intronic chr10:105506283(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SH3PXD2A	chr10:105452783(-) A-I intron -    21960545 chr10:105441512(-) C-T intron -    22484847 chr10:105441516(-) G-C intron -    22484847 chr10:105399149(-) G-A intron -    22484847 chr10:105414448(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SH3PXD2A	chr10:105354239-105354240(-) m6A 3'UTR       24981863 chr10:105354266-105354267(-) m6A 3'UTR       24981863//22608085 chr10:105354285-105354286(-) m6A 3'UTR       24981863//22608085 chr10:105354317-105354318(-) m6A 3'UTR       24981863//22608085 chr10:105354682-105354683(-) m6A 3'UTR       24284625//24981863 chr10:105354694-105354695(-) m6A 3'UTR       24284625//24981863 chr10:105354714-105354715(-) m6A 3'UTR       24284625//24981863 chr10:105354875-105354876(-) m6A 3'UTR       24284625 chr10:105355300-105355301(-) m6A 3'UTR       24981863 chr10:105355375-105355376(-) Y 3'UTR//intron       26075521 chr10:105356057-105356058(-) m6A 3'UTR       - chr10:105356356-105356357(-) m6A 3'UTR       24981863 chr10:105357397-105357398(-) m6A 3'UTR       24981863 chr10:105357473-105357474(-) m6A 3'UTR       24981863 chr10:105357521-105357522(-) m6A 3'UTR       24981863 chr10:105357533-105357534(-) m6A 3'UTR       24981863 chr10:105358122-105358123(-) m6A 3'UTR       27773535 chr10:105358192-105358193(-) m6A 3'UTR       27773535 chr10:105358625-105358626(-) m6A 3'UTR       27773535 chr10:105358634-105358635(-) m6A 3'UTR       27773535 chr10:105358696-105358697(-) m6A 3'UTR       27773535 chr10:105358903-105358904(-) m6A 3'UTR       27773535 chr10:105358910-105358911(-) m6A 3'UTR       27773535 chr10:105358957-105358958(-) m6A 3'UTR       27773535 chr10:105358967-105358968(-) m6A 3'UTR       27773535 chr10:105359021-105359022(-) m6A 3'UTR       27773535 chr10:105359105-105359106(-) m6A 3'UTR       - chr10:105359110-105359111(-) m6A 3'UTR       - chr10:105359778-105359779(-) m6A 3'UTR//exon       24209618//27773535 chr10:105359802-105359803(-) m6A 3'UTR//exon       24284625//24209618//27773535//22575960 chr10:105359879-105359880(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:105359925-105359926(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr10:105359973-105359974(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr10:105360006-105360007(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr10:105360088-105360089(-) m6A 3'UTR//exon       24284625//24209618//25456834//27371828//27773536//22575960//22608085 chr10:105360115-105360116(-) Y 3'UTR//exon//intron       26075521 chr10:105360213-105360214(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105360236-105360237(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360372-105360373(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360409-105360410(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360449-105360450(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360467-105360468(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360528-105360529(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105360795-105360796(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr10:105360858-105360859(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr10:105360930-105360931(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr10:105361203-105361204(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105361238-105361239(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105361254-105361255(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361284-105361285(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361326-105361327(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361348-105361349(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361460-105361461(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105361503-105361504(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105361576-105361577(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105361663-105361664(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361709-105361710(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361729-105361730(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105361849-105361850(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105361930-105361931(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105362005-105362006(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105362096-105362097(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362118-105362119(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362164-105362165(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362192-105362193(-) Am CDS//exon       - chr10:105362203-105362204(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362245-105362246(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105362407-105362408(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr10:105362625-105362626(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362653-105362654(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105362686-105362687(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105362834-105362835(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105362923-105362924(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085 chr10:105363007-105363008(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105363052-105363053(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105363082-105363083(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105363122-105363123(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr10:105363241-105363242(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105363337-105363338(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085 chr10:105363509-105363510(-) Cm CDS//exon       - chr10:105363532-105363533(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828 chr10:105365566-105365567(-) m6A CDS//exon       24284625//24981863//27773535//27371828 chr10:105371364-105371365(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105371369-105371370(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105371377-105371378(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105372675-105372676(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr10:105372786-105372787(-) m6A CDS//exon       24284625//25456834//27371828//27773536//22575960//22608085 chr10:105372794-105372795(-) m6A CDS//exon       24284625//25456834//27371828//27773536//22575960//22608085 chr10:105372812-105372813(-) m6A CDS//exon       24284625//27371828//27773536//22575960//22608085 chr10:105372839-105372840(-) m6A CDS//exon       24284625//27773535//27371828//27773536//22575960//22608085 chr10:105372869-105372870(-) m6A CDS//exon       24284625//27773535//27371828//27773536//22575960 chr10:105382262-105382263(-) m6A CDS//intron       24284625//24981863//27371828//27773536 chr10:105386854-105386855(-) m6A CDS//exon       24284625//24981863//27773535//27371828//27773536 chr10:105420799-105420800(-) m6A CDS//exon       24284625//27773535 chr10:105420837-105420838(-) m6A CDS//exon       24284625//27773535//22575960 chr10:105615108-105615109(-) m6A 5'UTR       24209618//27773536 chr10:105615174-105615175(-) m6A 5'UTR       27773536 chr10:105615197-105615198(-) m6A 5'UTR       27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SH3PXD2A	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART3-3p
Interactor2: SH3PXD2A

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//PITA//Targetscan
Support Database	RepTar//ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	Downregulation
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).