Basic Information:

  VIRBase ID:  

VHID00294257

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART2-5p:  MIMAT0001000          DBF4:  NM_001318061     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART2-5p	DBF4
miRBase Accession/Entrez ID	MIMAT0001000	10926
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ASK//CHIF//DBF4A//ZDBF1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DBF4	chr7:87535366(+) A-I      intronic chr7:87535344(+) A-I      intronic chr7:87527927(+) A-I      intronic chr7:87534366(+) A-I      intronic chr7:87533221(+) A-I      intronic chr7:87533220(+) A-I      intronic chr7:87533194(+) A-I      intronic chr7:87510571(+) A-I      intronic chr7:87510569(+) A-I      intronic chr7:87527943(+) A-I      intronic chr7:87527999(+) A-I      intronic chr7:87528002(+) A-I      intronic chr7:87518002(+) A-I      intronic chr7:87509147(+) A-I      intronic chr7:87528076(+) A-I      intronic chr7:87509115(+) A-I      intronic chr7:87508511(+) A-I      intronic chr7:87518612(+) A-I      intronic chr7:87518648(+) A-I      intronic chr7:87508484(+) A-I      intronic chr7:87522641(+) A-I      intronic chr7:87522700(+) A-I      intronic chr7:87522759(+) A-I      intronic chr7:87522767(+) A-I      intronic chr7:87522771(+) A-I      intronic chr7:87522820(+) A-I      intronic chr7:87508416(+) A-I      intronic chr7:87510444(+) A-I      intronic chr7:87508393(+) A-I      intronic chr7:87508337(+) A-I      intronic chr7:87518778(+) A-I      intronic chr7:87518675(+) A-I      intronic chr7:87509117(+) A-I      intronic chr7:87518816(+) A-I      intronic chr7:87519762(+) A-I      intronic chr7:87519767(+) A-I      intronic chr7:87523585(+) A-I      intronic chr7:87508516(+) A-I      intronic chr7:87509126(+) A-I      intronic chr7:87523700(+) A-I      intronic chr7:87519590(+) A-I      intronic chr7:87527145(+) A-I      intronic chr7:87523572(+) A-I      intronic chr7:87523628(+) A-I      intronic chr7:87513564(+) A-I      intronic chr7:87533937(+) A-I      intronic chr7:87533250(+) A-I      intronic chr7:87523575(+) A-I      intronic chr7:87523701(+) A-I      intronic chr7:87519684(+) A-I      intronic chr7:87534302(+) A-I      intronic chr7:87523644(+) A-I      intronic chr7:87509066(+) A-I      intronic chr7:87518664(+) A-I      intronic chr7:87527290(+) A-I      intronic chr7:87527293(+) A-I      intronic chr7:87518674(+) A-I      intronic chr7:87508332(+) A-I      intronic chr7:87527219(+) A-I      intronic chr7:87519779(+) A-I      intronic chr7:87523564(+) A-I      intronic chr7:87534359(+) A-I      intronic chr7:87527882(+) A-I      intronic chr7:87528069(+) A-I      intronic chr7:87527138(+) A-I      intronic chr7:87534395(+) A-I      intronic chr7:87534291(+) A-I      intronic chr7:87523509(+) A-I      intronic chr7:87519727(+) A-I      intronic chr7:87527111(+) A-I      intronic chr7:87527909(+) A-I      intronic chr7:87527197(+) A-I      intronic chr7:87535267(+) A-I      intronic chr7:87527193(+) A-I      intronic chr7:87533936(+) A-I      intronic chr7:87523584(+) A-I      intronic chr7:87509065(+) A-I      intronic chr7:87523632(+) A-I      intronic chr7:87519768(+) A-I      intronic chr7:87508492(+) A-I      intronic chr7:87527276(+) A-I      intronic chr7:87533136(+) A-I      intronic chr7:87527273(+) A-I      intronic chr7:87519726(+) A-I      intronic chr7:87510493(+) A-I      intronic chr7:87534405(+) A-I      intronic chr7:87527919(+) A-I      intronic chr7:87527218(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DBF4	chr7:87527138(+) A-I intron -    22327324 chr7:87523509(+) A-I intron -    22028664 chr7:87523521(+) A-I intron -    22028664 chr7:87523572(+) A-I intron -    22028664 chr7:87523575(+) A-I intron -    22028664 chr7:87523584(+) A-I intron -    22028664 chr7:87523585(+) A-I intron -    22028664 chr7:87523612(+) A-I intron -    22028664 chr7:87523628(+) A-I intron -    22028664 chr7:87523632(+) A-I intron -    22028664 chr7:87523644(+) A-I intron -    22028664 chr7:87523654(+) A-I intron -    22028664 chr7:87523700(+) A-I intron -    22028664 chr7:87523701(+) A-I intron -    22028664 chr7:87508332(+) A-G intron -    22484847 chr7:87508447(+) A-G intron -    22484847 chr7:87508492(+) A-G intron -    22484847 chr7:87509038(+) A-G intron -    22484847 chr7:87509041(+) T-C intron -    22484847 chr7:87509057(+) A-G intron -    22484847 chr7:87509065(+) A-G intron -    22484847 chr7:87509066(+) A-G intron -    22484847 chr7:87509126(+) A-G intron -    22484847 chr7:87518724(+) A-G intron -    22484847 chr7:87519590(+) A-G intron -    22484847 chr7:87519726(+) A-G intron -    22484847 chr7:87519727(+) A-G intron -    22484847 chr7:87519735(+) T-C intron -    22484847 chr7:87519768(+) A-G intron -    22484847 chr7:87523509(+) A-G intron -    22484847 chr7:87523584(+) A-G intron -    22484847 chr7:87523585(+) A-G intron -    22484847 chr7:87523654(+) A-G intron -    22484847 chr7:87523701(+) A-G intron -    22484847 chr7:87527138(+) A-G intron -    22484847 chr7:87527145(+) A-G intron -    22484847 chr7:87527210(+) A-G intron -    22484847 chr7:87527218(+) A-G intron -    22484847 chr7:87527230(+) T-C intron -    22484847 chr7:87527257(+) T-C intron -    22484847 chr7:87527268(+) T-C intron -    22484847 chr7:87527269(+) T-C intron -    22484847 chr7:87527276(+) A-G intron -    22484847 chr7:87527281(+) T-C intron -    22484847 chr7:87527290(+) A-G intron -    22484847 chr7:87527293(+) A-G intron -    22484847 chr7:87527345(+) A-G intron -    22484847 chr7:87527852(+) A-G intron -    22484847 chr7:87527882(+) A-G intron -    22484847 chr7:87528069(+) A-G intron -    22484847 chr7:87532420(+) T-C intron -    22484847 chr7:87533214(+) T-C intron -    22484847 chr7:87533974(+) T-C intron -    22484847 chr7:87534011(+) T-C intron -    22484847 chr7:87534291(+) A-G intron -    22484847 chr7:87534302(+) A-G intron -    22484847 chr7:87534359(+) A-G intron -    22484847 chr7:87535390(+) T-C intron -    22484847 chr7:87517988(+) A-G intron -    22484847 chr7:87517989(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DBF4	chr7:87505563-87505564(+) m6A 5'UTR       25456834 chr7:87505577-87505578(+) m6A 5'UTR       25456834 chr7:87505597-87505598(+) m6A 5'UTR       25456834 chr7:87505637-87505638(+) m6A 5'UTR       25456834 chr7:87505888-87505889(+) m6A 5'UTR//exon       24981863 chr7:87517316-87517317(+) m6A 3'UTR//CDS//exon       24981863 chr7:87525534-87525535(+) m6A exon//intron       24981863 chr7:87533712-87533713(+) m6A 3'UTR//CDS//exon       24981863//27773535//22608085 chr7:87536557-87536558(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87536562-87536563(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87536656-87536657(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87536665-87536666(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87536787-87536788(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:87536819-87536820(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:87536823-87536824(+) m6A 3'UTR//CDS       27773535//22575960 chr7:87536850-87536851(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:87536880-87536881(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:87536967-87536968(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:87537017-87537018(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:87537062-87537063(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:87537123-87537124(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:87537225-87537226(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87537250-87537251(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87537275-87537276(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87537311-87537312(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:87537322-87537323(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DBF4	Chromatin K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART2-5p	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 Dovitinib       135398510

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART2-5p
Interactor2: DBF4

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg