Basic Information:

  VIRBase ID:  

VHID00292880

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART2-5p:  MIMAT0001000          NEDD4:  NR_104302     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART2-5p	NEDD4
miRBase Accession/Entrez ID	MIMAT0001000	4734
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NEDD4-1//RPF1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NEDD4	chr15:56214705(-) A-I      intronic chr15:56279074(-) A-I      intronic chr15:56145045(-) A-I      intronic chr15:56149581(-) A-I      intronic chr15:56145085(-) A-I      intronic chr15:56145086(-) A-I      intronic chr15:56145099(-) A-I      intronic chr15:56146089(-) A-I      intronic chr15:56214779(-) A-I      intronic chr15:56149623(-) A-I      intronic chr15:56149624(-) A-I      intronic chr15:56146103(-) A-I      intronic chr15:56146106(-) A-I      intronic chr15:56275982(-) A-I      intronic chr15:56275154(-) A-I      intronic chr15:56146136(-) A-I      intronic chr15:56275281(-) A-I      intronic chr15:56275307(-) A-I      intronic chr15:56146801(-) A-I      intronic chr15:56146802(-) A-I      intronic chr15:56146814(-) A-I      intronic chr15:56276002(-) A-I      intronic chr15:56275988(-) A-I      intronic chr15:56278988(-) A-I      intronic chr15:56149557(-) A-I      intronic chr15:56149565(-) A-I      intronic chr15:56146820(-) A-I      intronic chr15:56146837(-) A-I      intronic chr15:56278863(-) A-I      intronic chr15:56278983(-) A-I      intronic chr15:56146141(-) A-I      intronic chr15:56150043(-) A-I      intronic chr15:56182157(-) A-I      intronic chr15:56182080(-) A-I      intronic chr15:56182063(-) A-I      intronic chr15:56182027(-) A-I      intronic chr15:56167015(-) A-I      intronic chr15:56172459(-) A-I      intronic chr15:56169182(-) A-I      intronic chr15:56169153(-) A-I      intronic chr15:56150733(-) A-I      intronic chr15:56275237(-) A-I      intronic chr15:56196780(-) A-I      intronic chr15:56126755(-) A-I      intronic chr15:56146157(-) A-I      intronic chr15:56146149(-) A-I      intronic chr15:56196750(-) A-I      intronic chr15:56129594(-) A-I      intronic chr15:56129425(-) A-I      intronic chr15:56129123(-) A-I      intronic chr15:56128901(-) A-I      intronic chr15:56128815(-) A-I      intronic chr15:56196743(-) A-I      intronic chr15:56126866(-) A-I      intronic chr15:56126809(-) A-I      intronic chr15:56196697(-) A-I      intronic chr15:56275238(-) A-I      intronic chr15:56275322(-) A-I      intronic chr15:56218774(-) A-I      intronic chr15:56126771(-) A-I      intronic chr15:56140081(-) A-I      intronic chr15:56150786(-) A-I      intronic chr15:56188491(-) A-I      intronic chr15:56275881(-) A-I      intronic chr15:56275886(-) A-I      intronic chr15:56227856(-) A-I      intronic chr15:56167090(-) A-I      intronic chr15:56278926(-) A-I      intronic chr15:56215373(-) A-I      intronic chr15:56278916(-) A-I      intronic chr15:56218761(-) A-I      intronic chr15:56276046(-) A-I      intronic chr15:56131329(-) A-I      intronic chr15:56276036(-) A-I      intronic chr15:56218748(-) A-I      intronic chr15:56188476(-) A-I      intronic chr15:56276027(-) A-I      intronic chr15:56218783(-) A-I      intronic chr15:56182174(-) A-I      intronic chr15:56215601(-) A-I      intronic chr15:56218820(-) A-I      intronic chr15:56275991(-) A-I      intronic chr15:56215273(-) A-I      intronic chr15:56213667(-) A-I      intronic chr15:56213661(-) A-I      intronic chr15:56213620(-) A-I      intronic chr15:56244408(-) A-I      intronic chr15:56244456(-) A-I      intronic chr15:56197228(-) A-I      intronic chr15:56275208(-) A-I      intronic chr15:56146024(-) A-I      intronic chr15:56227204(-) A-I      intronic chr15:56275198(-) A-I      intronic chr15:56144828(-) A-I      intronic chr15:56126858(-) A-I      intronic chr15:56215736(-) A-I      intronic chr15:56126792(-) A-I      intronic chr15:56126745(-) A-I      intronic chr15:56128888(-) A-I      intronic chr15:56196638(-) A-I      intronic chr15:56196238(-) A-I      intronic chr15:56227962(-) A-I      intronic chr15:56150634(-) A-I      intronic chr15:56167050(-) A-I      intronic chr15:56140060(-) A-I      intronic chr15:56126786(-) A-I      intronic chr15:56190972(-) A-I      intronic chr15:56214699(-) A-I      intronic chr15:56126785(-) A-I      intronic chr15:56227338(-) A-I      intronic chr15:56227832(-) A-I      intronic chr15:56126924(-) A-I      intronic chr15:56128761(-) A-I      intronic chr15:56275979(-) A-I      intronic chr15:56215368(-) A-I      intronic chr15:56128919(-) A-I      intronic chr15:56128939(-) A-I      intronic chr15:56129410(-) A-I      intronic chr15:56128899(-) A-I      intronic chr15:56128862(-) A-I      intronic chr15:56146014(-) A-I      intronic chr15:56169192(-) A-I      intronic chr15:56214658(-) A-I      intronic chr15:56128920(-) A-I      intronic chr15:56162730(-) A-I      intronic chr15:56145952(-) A-I      intronic chr15:56129506(-) A-I      intronic chr15:56215721(-) A-I      intronic chr15:56171218(-) A-I      intronic chr15:56275916(-) A-I      intronic chr15:56215330(-) A-I      intronic chr15:56126868(-) A-I      intronic chr15:56275075(-) A-I      intronic chr15:56227963(-) A-I      intronic chr15:56129056(-) A-I      intronic chr15:56278998(-) A-I      intronic chr15:56129045(-) A-I      intronic chr15:56215723(-) A-I      intronic chr15:56128993(-) A-I      intronic chr15:56275947(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NEDD4	chr15:56278998(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NEDD4	chr15:56119124-56119125(-) m6A 3'UTR       27773535 chr15:56119267-56119268(-) m6A 3'UTR       27773535 chr15:56119289-56119290(-) m6A 3'UTR       27773535 chr15:56119364-56119365(-) m6A 3'UTR       24981863//27773535 chr15:56119463-56119464(-) m6A 3'UTR       24981863//26404942//22608085 chr15:56119495-56119496(-) m6A 3'UTR       24981863//26404942//22608085 chr15:56119562-56119563(-) m6A 3'UTR       24981863//26404942 chr15:56120215-56120216(-) m6A 3'UTR       26404942 chr15:56120474-56120475(-) m6A 3'UTR       27773535 chr15:56120570-56120571(-) m6A 3'UTR       27773535 chr15:56120650-56120651(-) m6A 3'UTR       27773535 chr15:56122017-56122018(-) m6A 3'UTR       24981863 chr15:56122122-56122123(-) m6A 3'UTR//CDS       24981863 chr15:56134305-56134306(-) m6A 3'UTR//CDS       24981863 chr15:56134331-56134332(-) m6A 3'UTR//CDS       24981863 chr15:56134347-56134348(-) m6A 3'UTR//CDS       24981863 chr15:56140572-56140573(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56140616-56140617(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56140754-56140755(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56141041-56141042(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56142750-56142751(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56145676-56145677(-) Gm intron       16381836 chr15:56145677-56145678(-) Gm intron       16381836 chr15:56152890-56152891(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56152973-56152974(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56155121-56155122(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56155135-56155136(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56155152-56155153(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56155165-56155166(-) m6A 3'UTR//CDS       24981863//27773535 chr15:56207499-56207500(-) m6A CDS//intron       24981863 chr15:56207524-56207525(-) m6A CDS//intron       24981863 chr15:56207589-56207590(-) m6A CDS//intron       24981863//22608085 chr15:56207683-56207684(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207689-56207690(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207706-56207707(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207774-56207775(-) m6A CDS//intron       24981863//22575960//22608085 chr15:56207835-56207836(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207855-56207856(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207863-56207864(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56207943-56207944(-) m6A CDS//intron       24981863//27773535//22575960//22608085 chr15:56208010-56208011(-) m6A CDS//intron       24981863//22575960//22608085 chr15:56208038-56208039(-) m6A CDS//intron       24981863//22575960//22608085 chr15:56208054-56208055(-) m6A CDS//intron       24981863//22575960//22608085 chr15:56208146-56208147(-) m6A CDS//intron       24981863//22575960 chr15:56208265-56208266(-) m6A CDS//intron       24981863 chr15:56208303-56208304(-) m6A CDS//intron       24981863 chr15:56208376-56208377(-) m6A CDS//intron       24981863 chr15:56208415-56208416(-) m6A CDS//intron       24981863 chr15:56208867-56208868(-) m6A CDS//intron       24981863 chr15:56208965-56208966(-) m6A CDS//intron       24981863 chr15:56209032-56209033(-) m6A 5'UTR//intron       24981863 chr15:56209082-56209083(-) m6A 5'UTR//intron       24981863 chr15:56209163-56209164(-) m6A 5'UTR//intron       24981863 chr15:56209247-56209248(-) m6A 5'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NEDD4	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART2-5p	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 Dovitinib       135398510

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART2-5p
Interactor2: NEDD4

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg