Basic Information:

  VIRBase ID:  

VHID00292158

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART2-5p:  MIMAT0001000          CAST:  NR_104285     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART2-5p	CAST
miRBase Accession/Entrez ID	MIMAT0001000	831
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BS-17//PLACK

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CAST	chr5:96037459(+) A-I      intronic chr5:96008265(+) A-I      intronic chr5:96000204(+) A-I      intronic chr5:96000213(+) A-I      intronic chr5:96000228(+) A-I      intronic chr5:96008209(+) A-I      intronic chr5:96008235(+) A-I      intronic chr5:96008252(+) A-I      intronic chr5:96008264(+) A-I      intronic chr5:96012638(+) A-I      intronic chr5:96012655(+) A-I      intronic chr5:96014492(+) A-I      intronic chr5:96014735(+) A-I      intronic chr5:96014816(+) A-I      intronic chr5:96015797(+) A-I      intronic chr5:96015800(+) A-I      intronic chr5:96015944(+) A-I      intronic chr5:96015971(+) A-I      intronic chr5:96015980(+) A-I      intronic chr5:96015987(+) A-I      intronic chr5:96016008(+) A-I      intronic chr5:96016009(+) A-I      intronic chr5:96016014(+) A-I      intronic chr5:96016016(+) A-I      intronic chr5:96036798(+) A-I      intronic chr5:96036806(+) A-I      intronic chr5:96037323(+) A-I      intronic chr5:96037332(+) A-I      intronic chr5:96037333(+) A-I      intronic chr5:96037493(+) A-I      intronic chr5:96049503(+) A-I      intronic chr5:96049517(+) A-I      intronic chr5:96058701(+) A-I      intronic chr5:96058858(+) A-I      intronic chr5:96058866(+) A-I      intronic chr5:96058879(+) A-I      intronic chr5:96059946(+) A-I      intronic chr5:96059997(+) A-I      intronic chr5:96060087(+) A-I      intronic chr5:96060125(+) A-I      intronic chr5:96085325(+) A-I      intronic chr5:96093488(+) A-I      intronic chr5:96093494(+) A-I      intronic chr5:96093495(+) A-I      intronic chr5:96008201(+) A-I      intronic chr5:96037406(+) A-I      intronic chr5:96037415(+) A-I      intronic chr5:96037421(+) A-I      intronic chr5:96037429(+) A-I      intronic chr5:96037430(+) A-I      intronic chr5:96037450(+) A-I      intronic chr5:96036778(+) A-I      intronic chr5:96093595(+) A-I      intronic chr5:96090958(+) A-I      intronic chr5:96000241(+) A-I      intronic chr5:96032751(+) A-I      intronic chr5:96037389(+) A-I      intronic chr5:96036894(+) A-I      intronic chr5:96020454(+) A-I      intronic chr5:96049514(+) A-I      intronic chr5:96015938(+) A-I      intronic chr5:96060092(+) A-I      intronic chr5:96014824(+) A-I      intronic chr5:96060416(+) A-I      intronic chr5:96041048(+) A-I      intronic chr5:96008291(+) A-I      intronic chr5:96012555(+) A-I      intronic chr5:96032718(+) A-I      intronic chr5:96014807(+) A-I      intronic chr5:96060447(+) A-I      intronic chr5:96093578(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CAST	chr5:96000180(+) A-G intron -    22484847 chr5:96036761(+) A-G intron -    22484847 chr5:96036778(+) A-G intron -    22484847 chr5:96036894(+) A-G intron -    22484847 chr5:96037389(+) A-G intron -    22484847 chr5:96049514(+) A-G intron -    22484847 chr5:96060014(+) A-G intron -    22484847 chr5:96060092(+) A-G intron -    22484847 chr5:96060167(+) A-G intron -    22484847 chr5:96060273(+) A-G intron -    22484847 chr5:96060277(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CAST	chr5:95966713-95966714(+) m6A intron       - chr5:95997834-95997835(+) m6A 5'UTR//intron       24981863 chr5:95997960-95997961(+) m6A 5'UTR//intron       24981863 chr5:95997972-95997973(+) m6A 5'UTR//intron       24981863 chr5:95998056-95998057(+) m6A 5'UTR//intron       24209618//24981863 chr5:96011257-96011258(+) m6A 5'UTR//CDS//exon       24981863 chr5:96011277-96011278(+) m6A 5'UTR//CDS//exon       24981863 chr5:96011348-96011349(+) m6A exon//intron       24981863 chr5:96038538-96038539(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr5:96038570-96038571(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr5:96038581-96038582(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr5:96038593-96038594(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr5:96050359-96050360(+) m6A exon//intron       24284625//25456834//24981863 chr5:96050411-96050412(+) m6A exon//intron       24284625 chr5:96058396-96058397(+) m6A 5'UTR//CDS//exon//intron       24284625//24981863//27773535 chr5:96062526-96062527(+) m6A CDS//exon//intron       24284625//24981863//27773535 chr5:96062550-96062551(+) m6A CDS//exon//intron       24284625//24981863//27773535 chr5:96062559-96062560(+) m6A CDS//exon//intron       24284625//24981863//27773535 chr5:96063201-96063202(+) m6A CDS//intron       24284625//24981863//27773535 chr5:96063206-96063207(+) m6A CDS//intron       24284625//24981863//27773535 chr5:96064015-96064016(+) m6A exon//intron       24284625//24981863//27773535 chr5:96064903-96064904(+) m6A CDS//exon//intron       24284625//24981863//27773535//22608085 chr5:96065395-96065396(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//27773535//22608085 chr5:96065422-96065423(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22608085 chr5:96066488-96066489(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22608085 chr5:96066496-96066497(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22608085 chr5:96069929-96069930(+) Am intron       - chr5:96077233-96077234(+) m6A CDS//exon       24981863//22575960 chr5:96077346-96077347(+) m6A exon//intron       24981863 chr5:96078420-96078421(+) m6A CDS//exon       24981863//22575960 chr5:96079314-96079315(+) m6A 5'UTR//CDS//intron       24981863 chr5:96079445-96079446(+) m6A CDS//exon//intron       24981863 chr5:96082065-96082066(+) m6A CDS//exon//intron       24981863//27773535 chr5:96082093-96082094(+) m6A CDS//exon//intron       24981863//26404942//27773535 chr5:96082119-96082120(+) m6A CDS//exon//intron       24981863//26404942//27773535 chr5:96083062-96083063(+) m6A CDS//exon       24981863//27773535 chr5:96083089-96083090(+) m6A CDS//exon       24981863//27773535 chr5:96084238-96084239(+) m6A CDS//exon       24981863//27773535 chr5:96084250-96084251(+) m6A CDS//exon       24981863//27773535 chr5:96084289-96084290(+) m6A CDS//exon       24981863 chr5:96084311-96084312(+) m6A CDS//exon       24981863 chr5:96086338-96086339(+) m6A CDS//exon       22575960 chr5:96089824-96089825(+) Cm CDS//exon       - chr5:96089843-96089844(+) m6A CDS//exon       24981863//27773535//22575960 chr5:96090380-96090381(+) m6A CDS//exon       24981863//27773535//22575960 chr5:96090409-96090410(+) m6A CDS//exon       24981863//27773535//22575960 chr5:96090449-96090450(+) m6A exon//intron       24284625//24981863//27773535 chr5:96090504-96090505(+) m6A exon//intron       24284625//24981863 chr5:96090520-96090521(+) m6A exon//intron       24981863 chr5:96090525-96090526(+) m6A exon//intron       24981863 chr5:96090561-96090562(+) m6A exon//intron       24981863 chr5:96090845-96090846(+) m6A exon//intron       24981863 chr5:96090868-96090869(+) m6A exon//intron       24981863 chr5:96093188-96093189(+) m6A CDS//exon       24981863 chr5:96093299-96093300(+) m6A CDS//exon       24981863 chr5:96093326-96093327(+) m6A CDS//exon       24981863 chr5:96100937-96100938(+) m6A CDS//exon       24981863//26404942//27773535 chr5:96100959-96100960(+) m6A CDS//exon       24981863//26404942//27773535 chr5:96100977-96100978(+) m6A CDS//exon       24981863//26404942//27773535 chr5:96101003-96101004(+) m6A CDS//exon       24981863//26404942//27773535 chr5:96101773-96101774(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96101781-96101782(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96101824-96101825(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96101845-96101846(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96103146-96103147(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96103612-96103613(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96103629-96103630(+) m6A CDS//exon       24981863//26404942//27773535//22575960 chr5:96103659-96103660(+) m6A CDS//exon       24981863//26404942//27773535 chr5:96103682-96103683(+) m6A CDS//exon       26404942//27773535 chr5:96103692-96103693(+) m6A CDS//exon       26404942//27773535 chr5:96107359-96107360(+) m6A CDS//exon       24981863//26404942 chr5:96107435-96107436(+) m6A exon//intron       26404942 chr5:96109517-96109518(+) m6A 3'UTR//intron       - chr5:96109620-96109621(+) m6A 3'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CAST	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART2-5p	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 Dovitinib       135398510

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART2-5p
Interactor2: CAST

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg