Basic Information:

  VIRBase ID:  

VHID00289495

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6055

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART1-5p:  MIMAT0000999          WARS1:  NM_213645     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART1-5p	WARS1
miRBase Accession/Entrez ID	MIMAT0000999	7453
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GAMMA-2//HMN9//IFI53//IFP53//WARS

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WARS1	chr14:100818676(-) A-I      intronic chr14:100826443(-) A-I      intronic chr14:100837735(-) A-I      intronic chr14:100836104(-) A-I      intronic chr14:100817772(-) A-I      intronic chr14:100816643(-) A-I      intronic chr14:100805287(-) A-I      intronic chr14:100805021(-) A-I      intronic chr14:100804741(-) A-I      intronic chr14:100804800(-) A-I      intronic chr14:100804802(-) A-I      intronic chr14:100804817(-) A-I      intronic chr14:100804820(-) A-I      intronic chr14:100804822(-) A-I      intronic chr14:100804964(-) A-I      intronic chr14:100807503(-) A-I      intronic chr14:100818643(-) A-I      intronic chr14:100818644(-) A-I      intronic chr14:100818284(-) A-I      intronic chr14:100829867(-) A-I      intronic chr14:100836112(-) A-I      intronic chr14:100804948(-) A-I      intronic chr14:100836176(-) A-I      intronic chr14:100805815(-) A-I      intronic chr14:100807389(-) A-I      intronic chr14:100829861(-) A-I      intronic chr14:100802439(-) A-I      intronic chr14:100819728(-) A-I      intronic chr14:100819666(-) A-I      intronic chr14:100830230(-) A-I      intronic chr14:100830163(-) A-I      intronic chr14:100807457(-) A-I      intronic chr14:100807357(-) A-I      intronic chr14:100818736(-) A-I      intronic chr14:100804854(-) A-I      intronic chr14:100801859(-) A-I      intronic chr14:100837218(-) A-I      intronic chr14:100805399(-) A-I      intronic chr14:100819763(-) A-I      intronic chr14:100805380(-) A-I      intronic chr14:100837704(-) A-I      intronic chr14:100818719(-) A-I      intronic chr14:100818690(-) A-I      intronic chr14:100805335(-) A-I      intronic chr14:100837996(-) A-I      intronic chr14:100818141(-) A-I      intronic chr14:100801942(-) A-I      intronic chr14:100818652(-) A-I      intronic chr14:100804770(-) A-I      intronic chr14:100801875(-) A-I      intronic chr14:100804762(-) A-I      intronic chr14:100804735(-) A-I      intronic chr14:100818750(-) A-I      intronic chr14:100818613(-) A-I      intronic chr14:100804679(-) A-I      intronic chr14:100804895(-) A-I      intronic chr14:100804883(-) A-I      intronic chr14:100805299(-) A-I      intronic chr14:100805276(-) A-I      intronic chr14:100809478(-) A-I      intronic chr14:100804022(-) A-I      intronic chr14:100805201(-) A-I      intronic chr14:100818208(-) A-I      intronic chr14:100816685(-) A-I      intronic chr14:100805200(-) A-I      intronic chr14:100805011(-) A-I      intronic chr14:100804797(-) A-I      intronic chr14:100818166(-) A-I      intronic chr14:100804876(-) A-I      intronic chr14:100804871(-) A-I      intronic chr14:100818637(-) A-I      intronic chr14:100818618(-) A-I      intronic chr14:100836277(-) A-I      intronic chr14:100818577(-) A-I      intronic chr14:100802698(-) A-I      intronic chr14:100804989(-) A-I      intronic chr14:100807363(-) A-I      intronic chr14:100804953(-) A-I      intronic chr14:100804823(-) A-I      intronic chr14:100807324(-) A-I      intronic chr14:100804773(-) A-I      intronic chr14:100818557(-) A-I      intronic chr14:100818074(-) A-I      intronic chr14:100818617(-) A-I      intronic chr14:100818273(-) A-I      intronic chr14:100807328(-) A-I      intronic chr14:100806907(-) A-I      intronic chr14:100805261(-) A-I      intronic chr14:100804727(-) A-I      intronic chr14:100802513(-) A-I      intronic chr14:100818267(-) A-I      intronic chr14:100818246(-) A-I      intronic chr14:100817744(-) A-I      intronic chr14:100804987(-) A-I      intronic chr14:100818230(-) A-I      intronic chr14:100818222(-) A-I      intronic chr14:100818211(-) A-I      intronic chr14:100818206(-) A-I      intronic chr14:100818163(-) A-I      intronic chr14:100818161(-) A-I      intronic chr14:100818117(-) A-I      intronic chr14:100818112(-) A-I      intronic chr14:100837280(-) A-I      intronic chr14:100817745(-) A-I      intronic chr14:100807532(-) A-I      intronic chr14:100807499(-) A-I      intronic chr14:100807427(-) A-I      intronic chr14:100802501(-) A-I      intronic chr14:100807412(-) A-I      intronic chr14:100807392(-) A-I      intronic chr14:100804949(-) A-I      intronic chr14:100805343(-) A-I      intronic chr14:100838020(-) A-I      intronic chr14:100804700(-) A-I      intronic chr14:100838009(-) A-I      intronic chr14:100837989(-) A-I      intronic chr14:100837985(-) A-I      intronic chr14:100837909(-) A-I      intronic chr14:100801882(-) A-I      intronic chr14:100801863(-) A-I      intronic chr14:100837724(-) A-I      intronic chr14:100836183(-) A-I      intronic chr14:100814160(-) A-I      intronic chr14:100836179(-) A-I      intronic chr14:100836178(-) A-I      intronic chr14:100836177(-) A-I      intronic chr14:100836174(-) A-I      intronic chr14:100838028(-) A-I      intronic chr14:100836169(-) A-I      intronic chr14:100836149(-) A-I      intronic chr14:100835259(-) A-I      intronic chr14:100831915(-) A-I      intronic chr14:100816702(-) A-I      intronic chr14:100831857(-) A-I      intronic chr14:100831754(-) A-I      intronic chr14:100831734(-) A-I      intronic chr14:100830236(-) A-I      intronic chr14:100818083(-) A-I      intronic chr14:100830167(-) A-I      intronic chr14:100837180(-) A-I      intronic chr14:100830131(-) A-I      intronic chr14:100802011(-) A-I      intronic chr14:100836106(-) A-I      intronic chr14:100833916(-) A-I      intronic chr14:100831720(-) A-I      intronic chr14:100805038(-) A-I      intronic chr14:100804975(-) A-I      intronic chr14:100818545(-) A-I      intronic chr14:100817798(-) A-I      intronic chr14:100802423(-) A-I      intronic chr14:100831903(-) A-I      intronic chr14:100805199(-) A-I      intronic chr14:100801950(-) A-I      intronic chr14:100830096(-) A-I      intronic chr14:100814051(-) A-I      intronic chr14:100830223(-) A-I      intronic chr14:100835189(-) A-I      intronic chr14:100807539(-) A-I      intronic chr14:100817754(-) A-I      intronic chr14:100804743(-) A-I      intronic chr14:100803953(-) A-I      intronic chr14:100801995(-) A-I      intronic chr14:100818283(-) A-I      intronic chr14:100814751(-) A-I      intronic chr14:100802418(-) A-I      intronic chr14:100829850(-) A-I      intronic chr14:100818182(-) A-I      intronic chr14:100815192(-) A-I      intronic chr14:100805761(-) A-I      intronic chr14:100804766(-) A-I      intronic chr14:100805342(-) A-I      intronic chr14:100830235(-) A-I      intronic chr14:100807337(-) A-I      intronic chr14:100805187(-) A-I      intronic chr14:100837705(-) A-I      intronic chr14:100805278(-) A-I      intronic chr14:100836111(-) A-I      intronic chr14:100826432(-) A-I      intronic chr14:100818619(-) A-I      intronic chr14:100804877(-) A-I      intronic chr14:100837892(-) A-I      intronic chr14:100819702(-) A-I      intronic chr14:100829918(-) A-I      intronic chr14:100833153(-) A-I      intronic chr14:100818086(-) A-I      intronic chr14:100805504(-) A-I      intronic chr14:100821382(-) A-I      intronic chr14:100801839(-) A-I      intronic chr14:100807525(-) A-I      intronic chr14:100804855(-) A-I      intronic chr14:100837197(-) A-I      intronic chr14:100802645(-) A-I      intronic chr14:100836083(-) A-I      intronic chr14:100809237(-) A-I      intronic chr14:100818653(-) A-I      intronic chr14:100805044(-) A-I      intronic chr14:100801852(-) A-I      intronic chr14:100801853(-) A-I      intronic chr14:100805739(-) A-I      intronic chr14:100818218(-) A-I      intronic chr14:100829886(-) A-I      intronic chr14:100830214(-) A-I      intronic chr14:100818254(-) A-I      intronic chr14:100807431(-) A-I      intronic chr14:100836226(-) A-I      intronic chr14:100807416(-) A-I      intronic chr14:100805240(-) A-I      intronic chr14:100805331(-) A-I      intronic chr14:100804004(-) A-I      intronic chr14:100818172(-) A-I      intronic chr14:100818308(-) A-I      intronic chr14:100802356(-) A-I      intronic chr14:100802368(-) A-I      intronic chr14:100831406(-) A-I      intronic chr14:100801888(-) A-I      intronic chr14:100817732(-) A-I      intronic chr14:100818642(-) A-I      intronic chr14:100837223(-) A-I      intronic chr14:100805404(-) A-I      intronic chr14:100802921(-) A-I      intronic chr14:100804936(-) A-I      intronic chr14:100818328(-) A-I      intronic chr14:100807528(-) A-I      intronic chr14:100819858(-) A-I      intronic chr14:100804944(-) A-I      intronic chr14:100804868(-) A-I      intronic chr14:100807341(-) A-I      intronic chr14:100830258(-) A-I      intronic chr14:100837274(-) A-I      intronic chr14:100823915(-) A-I      intronic chr14:100829885(-) A-I      intronic chr14:100805022(-) A-I      intronic chr14:100802723(-) A-I      intronic chr14:100804950(-) A-I      intronic chr14:100831369(-) A-I      intronic chr14:100818243(-) A-I      intronic chr14:100801994(-) A-I      intronic chr14:100807312(-) A-I      intronic chr14:100818087(-) A-I      intronic chr14:100837622(-) A-I      intronic chr14:100818622(-) A-I      intronic chr14:100836082(-) A-I      intronic chr14:100818221(-) A-I      intronic chr14:100830238(-) A-I      intronic chr14:100807396(-) A-I      intronic chr14:100818728(-) A-I      intronic chr14:100817807(-) A-I      intronic chr14:100829776(-) A-I      intronic chr14:100818727(-) A-I      intronic chr14:100819752(-) A-I      intronic chr14:100819806(-) A-I      intronic chr14:100804965(-) A-I      intronic chr14:100837701(-) A-I      intronic chr14:100835149(-) A-I      intronic chr14:100836281(-) A-I      intronic chr14:100805865(-) A-I      intronic chr14:100829894(-) A-I      intronic chr14:100801918(-) A-I      intronic chr14:100804860(-) A-I      intronic chr14:100805232(-) A-I      intronic chr14:100802705(-) A-I      intronic chr14:100830165(-) A-I      intronic chr14:100836220(-) A-I      intronic chr14:100818560(-) A-I      intronic chr14:100818181(-) A-I      intronic chr14:100801777(-) A-I      intronic chr14:100833911(-) A-I      intronic chr14:100819857(-) A-I      intronic chr14:100837905(-) A-I      intronic chr14:100830190(-) A-I      intronic chr14:100803942(-) A-I      intronic chr14:100837827(-) A-I      intronic chr14:100837198(-) A-I      intronic chr14:100818587(-) A-I      intronic chr14:100837990(-) A-I      intronic chr14:100830128(-) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	WARS1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART1-5p	Panobinostat       6918837 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART1-5p
Interactor2: WARS1

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//PITA//Targetscan
Support Database	RepTar//ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).