Detail Information

Basic Information:


  VIRBase ID:  

VHID00289411

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8847

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART1-5p:           SUOX:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART1-5p SUOX
miRBase
Accession/Entrez ID		 MIMAT0000999 6821
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SUOX
chr12:56392758(+) A-I      intronic
chr12:56397234(+) A-I      intronic
chr12:56397185(+) A-I      intronic
chr12:56397175(+) A-I      intronic
chr12:56397146(+) A-I      intronic
chr12:56397123(+) A-I      intronic
chr12:56397115(+) A-I      intronic
chr12:56393052(+) A-I      intronic
chr12:56393006(+) A-I      intronic
chr12:56392512(+) A-I      intronic
chr12:56392224(+) A-I      intronic
chr12:56392859(+) A-I      intronic
chr12:56392726(+) A-I      intronic
chr12:56392652(+) A-I      intronic
chr12:56392123(+) A-I      intronic
chr12:56392434(+) A-I      intronic
chr12:56395054(+) A-I      intronic
chr12:56392148(+) A-I      intronic
chr12:56392795(+) A-I      intronic
chr12:56392736(+) A-I      intronic
chr12:56392479(+) A-I      intronic
chr12:56392662(+) A-I      intronic
chr12:56392131(+) A-I      intronic
chr12:56392379(+) A-I      intronic
chr12:56392536(+) A-I      intronic
chr12:56392607(+) A-I      intronic
chr12:56392463(+) A-I      intronic
chr12:56392104(+) A-I      intronic
chr12:56392438(+) A-I      intronic
chr12:56392683(+) A-I      intronic
chr12:56392200(+) A-I      intronic
chr12:56395170(+) A-I      intronic
chr12:56393015(+) A-I      intronic
chr12:56392781(+) A-I      intronic
chr12:56392731(+) A-I      intronic
chr12:56392987(+) A-I      intronic
chr12:56392151(+) A-I      intronic
chr12:56393023(+) A-I      intronic
chr12:56392233(+) A-I      intronic
chr12:56392798(+) A-I      intronic
chr12:56392545(+) A-I      intronic
chr12:56393010(+) A-I      intronic
chr12:56392202(+) A-I      intronic
chr12:56397306(+) A-I      intronic
chr12:56393064(+) A-I      intronic
chr12:56392110(+) A-I      intronic
chr12:56392175(+) A-I      intronic
chr12:56392467(+) A-I      intronic
chr12:56392315(+) A-I      intronic
chr12:56392653(+) A-I      intronic
chr12:56392808(+) A-I      intronic
chr12:56392419(+) A-I      intronic
chr12:56392861(+) A-I      intronic
chr12:56392860(+) A-I      intronic
chr12:56392374(+) A-I      intronic
chr12:56392511(+) A-I      intronic
chr12:56397255(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SUOX
chr12:56393023(+) A-I intron -    22327324
chr12:56392200(+) A-I intron -    21960545
chr12:56392463(+) A-I intron -    21960545
chr12:56392652(+) A-I intron -    21960545
chr12:56392662(+) A-I intron -    21960545
chr12:56392652(+) A-G intron -    22484847
chr12:56392798(+) A-G intron -    22484847
chr12:56392861(+) A-G intron -    22484847
chr12:56393023(+) A-G intron -    22484847
chr12:56396577(+) A-G intron -    22484847
chr12:56396684(+) A-G intron -    22484847
chr12:56392463(+) A-G intron -    22484847
chr12:56392607(+) A-G intron -    22484847
chr12:56392662(+) A-G intron -    22484847
chr12:56392808(+) A-G intron -    22484847
chr12:56392860(+) A-G intron -    22484847
chr12:56393010(+) A-G intron -    22484847
chr12:56396643(+) A-G intron -    22484847
chr12:56396730(+) A-G intron -    22484847
chr12:56397255(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SUOX
chr12:56391040-56391041(+) m6A 5'UTR       24981863
chr12:56391073-56391074(+) m6A 5'UTR//exon       24284625//24981863
chr12:56391111-56391112(+) m6A 5'UTR//exon       24284625//24981863
chr12:56391118-56391119(+) m6A 5'UTR//exon       24284625//24981863
chr12:56391131-56391132(+) m6A 5'UTR//intron       24284625//24981863
chr12:56396533-56396534(+) m6A exon//intron       22608085
chr12:56396806-56396807(+) m6A exon//intron       25456834//24981863//22608085
chr12:56397464-56397465(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085
chr12:56397519-56397520(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085
chr12:56397663-56397664(+) m6A CDS//exon//intron       24284625//24981863
chr12:56397686-56397687(+) m6A CDS//exon//intron       24284625//24981863
chr12:56397789-56397790(+) m6A CDS//exon//intron       24284625//24981863//22608085
chr12:56397825-56397826(+) m6A CDS//exon//intron       24284625//24981863//22608085
chr12:56397855-56397856(+) m6A CDS//intron       24284625//24981863//22608085
chr12:56398025-56398026(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398106-56398107(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398132-56398133(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398137-56398138(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398143-56398144(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398154-56398155(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398194-56398195(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398395-56398396(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398403-56398404(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398438-56398439(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398481-56398482(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398609-56398610(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr12:56398672-56398673(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398681-56398682(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398686-56398687(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:56398731-56398732(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr12:56398752-56398753(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr12:56398958-56398959(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr12:56398973-56398974(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr12:56399005-56399006(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr12:56399069-56399070(+) m6A 3'UTR//intron       24284625//24981863//22608085
chr12:56399081-56399082(+) Y 3'UTR//intron       26075521

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate SUOX
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug ebv-miR-BART1-5p
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
Dovitinib       135398510
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART1-5p
Interactor2: SUOX

Evidence Support:


Strong-Evidence Luciferase reporter assay
Weak-Evidence PAR-CLIP
Prediction-Evidence PARalyzer
Support Database ViRBase//VIRmiRNA

References:


PMID 22291592 Target region CDS
Source ViRBase//VIRmiRNA Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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