Basic Information:

  VIRBase ID:  

VHID00288083

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-3:  MIMAT0000998          FBRS:  NM_001105079     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-3	FBRS
miRBase Accession/Entrez ID	MIMAT0000998	64319
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	FBS//FBS1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FBRS	chr16:30669827-30669828(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr16:30669839-30669840(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr16:30669910-30669911(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr16:30669936-30669937(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr16:30669952-30669953(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr16:30670117-30670118(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670126-30670127(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670181-30670182(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670198-30670199(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670293-30670294(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670300-30670301(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670342-30670343(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670349-30670350(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670383-30670384(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670390-30670391(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr16:30670472-30670473(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr16:30670520-30670521(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr16:30670556-30670557(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr16:30670786-30670787(+) m6A 5'UTR       24209618 chr16:30670921-30670922(+) m6A CDS       24209618 chr16:30670927-30670928(+) m6A CDS       24209618 chr16:30671099-30671100(+) m6A CDS       24209618//25456834//27371828 chr16:30671245-30671246(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828 chr16:30671618-30671619(+) m6A CDS//exon       24284625//24209618//25456834//24981863 chr16:30671686-30671687(+) m6A CDS//exon       24981863 chr16:30671781-30671782(+) m6A exon//intron       - chr16:30671847-30671848(+) m6A exon//intron       - chr16:30671853-30671854(+) m6A exon//intron       - chr16:30673909-30673910(+) m6A CDS//exon       24284625//24981863 chr16:30673922-30673923(+) m6A CDS//exon       24284625//24209618//24981863 chr16:30673967-30673968(+) m6A CDS//exon       24284625//24209618//24981863 chr16:30674015-30674016(+) m6A CDS//exon       24284625//24209618//25456834//24981863 chr16:30674164-30674165(+) m6A CDS//exon       24284625//24209618//25456834//24981863 chr16:30676041-30676042(+) m6A 5'UTR//CDS//intron       24284625 chr16:30676056-30676057(+) m6A 5'UTR//CDS//intron       24284625 chr16:30676062-30676063(+) m6A 5'UTR//CDS//intron       24284625 chr16:30676965-30676966(+) m6A CDS//intron       - chr16:30677021-30677022(+) m6A CDS//intron       - chr16:30677336-30677337(+) m6A exon//intron       - chr16:30677642-30677643(+) m6A exon//intron       - chr16:30677669-30677670(+) m6A exon//intron       - chr16:30678914-30678915(+) m6A 3'UTR//CDS//exon       24284625 chr16:30679304-30679305(+) m6A exon//intron       24284625 chr16:30680039-30680040(+) m6A exon//intron       24284625 chr16:30680229-30680230(+) m6A 3'UTR//CDS//exon       - chr16:30680242-30680243(+) m6A 3'UTR//CDS//exon       - chr16:30680296-30680297(+) m6A 3'UTR//CDS//exon       - chr16:30680391-30680392(+) m6A 3'UTR//CDS//exon       - chr16:30680487-30680488(+) Gm 3'UTR//CDS//exon       - chr16:30680740-30680741(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863 chr16:30680779-30680780(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863 chr16:30680843-30680844(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863 chr16:30680864-30680865(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834 chr16:30681094-30681095(+) m6A 3'UTR//exon       24209618 chr16:30681102-30681103(+) m6A 3'UTR//exon       24209618 chr16:30681125-30681126(+) m6A 3'UTR//exon       24209618 chr16:30681552-30681553(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr16:30681578-30681579(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr16:30681637-30681638(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr16:30681645-30681646(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr16:30681759-30681760(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr16:30681816-30681817(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr16:30681839-30681840(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085 chr16:30681854-30681855(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	FBRS	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-3
Interactor2: FBRS

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).