Basic Information:

  VIRBase ID:  

VHID00287362

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-3:  MIMAT0000998          RPL11:  NM_000975     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-3	RPL11
miRBase Accession/Entrez ID	MIMAT0000998	6135
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	DBA7//GIG34//L11//uL5

RNA Editing:

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RPL11	chr1:24022909(+) T-A intron -    21725310 chr1:24020881(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RPL11	chr1:24019120-24019121(+) m6A CDS//exon       27773535//22575960 chr1:24019133-24019134(+) m6A CDS//exon       27773535//22575960 chr1:24019148-24019149(+) m6A CDS//exon       27773535//22575960 chr1:24019183-24019184(+) m6A CDS//exon       27773535//22575960 chr1:24019193-24019194(+) Gm CDS//exon       - chr1:24019230-24019231(+) m6A CDS//exon       27773535//22575960 chr1:24020342-24020343(+) Tm CDS//exon       - chr1:24021174-24021175(+) m6A CDS//exon       26404942//27773535//22575960 chr1:24021195-24021196(+) m6A CDS//exon       26404942//27773535//22575960 chr1:24021217-24021218(+) m6A CDS//exon       26404942//27773535//22575960 chr1:24021270-24021271(+) m6A CDS//exon       26404942//27773535//22575960 chr1:24021797-24021798(+) m6A 3'UTR//intron       22575960 chr1:24021825-24021826(+) m6A 3'UTR//intron       22575960 chr1:24021841-24021842(+) m6A 3'UTR//intron       22575960 chr1:24021869-24021870(+) m6A 3'UTR//intron       27773535//22575960 chr1:24022318-24022319(+) m6A CDS//exon       27773535//22575960 chr1:24022332-24022333(+) m6A CDS//exon       27773535//22575960 chr1:24022352-24022353(+) m6A CDS//exon       27773535//22575960 chr1:24022563-24022564(+) m6A 3'UTR//intron       - chr1:24022572-24022573(+) m6A 3'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RPL11	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-3
Interactor2: RPL11

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).