Detail Information

Basic Information:


  VIRBase ID:  

VHID00286328

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-3p:           IFFO2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BHRF1-2-3p IFFO2
miRBase
Accession/Entrez ID		 MIMAT0000997 126917
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR IFFO2
chr1:19260700(-) A-I      intronic
chr1:19260702(-) A-I      intronic
chr1:19260685(-) A-I      intronic
chr1:19241265(-) A-I      intronic
chr1:19240597(-) A-I      intronic
chr1:19242591(-) A-I      intronic
chr1:19240598(-) A-I      intronic
chr1:19273170(-) A-I      intronic
chr1:19240571(-) A-I      intronic
chr1:19240392(-) A-I      intronic
chr1:19240490(-) A-I      intronic
chr1:19240592(-) A-I      intronic
chr1:19242611(-) A-I      intronic
chr1:19240464(-) A-I      intronic
chr1:19242507(-) A-I      intronic
chr1:19260677(-) A-I      intronic
chr1:19269921(-) A-I      intronic
chr1:19260760(-) A-I      intronic
chr1:19269757(-) A-I      intronic
chr1:19268797(-) A-I      intronic
chr1:19242583(-) A-I      intronic
chr1:19260673(-) A-I      intronic
chr1:19262295(-) A-I      intronic
chr1:19262300(-) A-I      intronic
chr1:19260094(-) A-I      intronic
chr1:19269873(-) A-I      intronic
chr1:19270065(-) A-I      intronic
chr1:19260157(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED IFFO2
chr1:19240464(-) A-G intron -    22484847
chr1:19242611(-) A-G intron -    22484847
chr1:19269757(-) A-G intron -    22484847
chr1:19269873(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IFFO2
chr1:19230976-19230977(-) m6A 3'UTR       27773535
chr1:19231028-19231029(-) m6A 3'UTR       -
chr1:19231080-19231081(-) m6A 3'UTR       -
chr1:19231930-19231931(-) m6A 3'UTR       -
chr1:19232024-19232025(-) m6A 3'UTR       -
chr1:19232067-19232068(-) m6A 3'UTR       -
chr1:19232159-19232160(-) m6A 3'UTR       27773535
chr1:19232166-19232167(-) m6A 3'UTR       27773535
chr1:19232250-19232251(-) m6A 3'UTR       -
chr1:19232276-19232277(-) m6A 3'UTR       -
chr1:19234333-19234334(-) m6A 3'UTR       24981863
chr1:19234338-19234339(-) m6A 3'UTR       24981863
chr1:19234353-19234354(-) m6A 3'UTR       24981863
chr1:19234395-19234396(-) m6A 3'UTR       24981863
chr1:19234440-19234441(-) m6A 3'UTR       24981863
chr1:19234497-19234498(-) m6A 3'UTR       -
chr1:19234697-19234698(-) m6A 3'UTR       24981863//27773535
chr1:19234784-19234785(-) m6A 3'UTR       24284625//24981863//27773535
chr1:19234796-19234797(-) m6A 3'UTR       24284625//24981863//27773535
chr1:19234909-19234910(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536
chr1:19234946-19234947(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536
chr1:19236838-19236839(-) m6A CDS       27371828
chr1:19236869-19236870(-) m6A CDS       27371828
chr1:19236934-19236935(-) m6A CDS       27773535
chr1:19237911-19237912(-) m6A CDS//intron       27773535
chr1:19237936-19237937(-) m6A CDS//intron       27773535
chr1:19237959-19237960(-) m6A CDS//intron       27773535
chr1:19238517-19238518(-) m6A CDS       27773535
chr1:19238569-19238570(-) m6A CDS       24981863//27773535
chr1:19243432-19243433(-) m6A CDS       24981863//27773535
chr1:19243465-19243466(-) m6A CDS       27773535
chr1:19244883-19244884(-) m6A CDS//intron       27773535
chr1:19244940-19244941(-) m6A CDS//intron       24981863//27773535
chr1:19244946-19244947(-) m6A CDS//intron       24981863//27773535
chr1:19244979-19244980(-) m6A CDS//intron       24209618//24981863
chr1:19244985-19244986(-) m6A CDS//intron       24209618//24981863
chr1:19247567-19247568(-) m6A CDS       24209618//24981863//27371828
chr1:19247577-19247578(-) m6A CDS       24209618//24981863//27371828
chr1:19247585-19247586(-) m6A CDS       24209618//24981863//27371828
chr1:19282297-19282298(-) m6A CDS       24209618//27773536
chr1:19282348-19282349(-) m6A CDS       27773536
chr1:19282501-19282502(-) m6A CDS       27773536
chr1:19282528-19282529(-) m6A CDS       27773536
chr1:19282818-19282819(-) m6A CDS       24209618//24981863//27773536
chr1:19282948-19282949(-) m6A 5'UTR       24209618//27371828//27773536
chr1:19283095-19283096(-) m6A 5'UTR       24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BHRF1-2-3p
Exosome K562 cells     24460325
IFFO2
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BHRF1-2-3p
Interactor2: IFFO2

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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