Basic Information:

  VIRBase ID:  

VHID00286143

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-3p:  MIMAT0000997          ANKRD13A:  NM_033121     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-3p	ANKRD13A
miRBase Accession/Entrez ID	MIMAT0000997	88455
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ANKRD13//NY-REN-25

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ANKRD13A	chr12:110443016(+) A-I      intronic chr12:110453491(+) A-I      intronic chr12:110462929(+) A-I      intronic chr12:110453469(+) A-I      intronic chr12:110453388(+) A-I      intronic chr12:110447861(+) A-I      intronic chr12:110462977(+) A-I      intronic chr12:110472382(+) A-I      intronic chr12:110472381(+) A-I      intronic chr12:110472342(+) A-I      intronic chr12:110472328(+) A-I      intronic chr12:110453493(+) A-I      intronic chr12:110453554(+) A-I      intronic chr12:110470890(+) A-I      intronic chr12:110464044(+) A-I      intronic chr12:110468749(+) A-I      intronic chr12:110454673(+) A-I      intronic chr12:110444505(+) A-I      intronic chr12:110453445(+) A-I      intronic chr12:110468780(+) A-I      intronic chr12:110463884(+) A-I      intronic chr12:110471074(+) A-I      intronic chr12:110469341(+) A-I      intronic chr12:110471079(+) A-I      intronic chr12:110454601(+) A-I      intronic chr12:110464218(+) A-I      intronic chr12:110468645(+) A-I      intronic chr12:110468794(+) A-I      intronic chr12:110453860(+) A-I      intronic chr12:110464227(+) A-I      intronic chr12:110447148(+) A-I      intronic chr12:110463989(+) A-I      intronic chr12:110473177(+) A-I      intronic chr12:110455011(+) A-I      intronic chr12:110469256(+) A-I      intronic chr12:110469218(+) A-I      intronic chr12:110440175(+) A-I      intronic chr12:110440183(+) A-I      intronic chr12:110440236(+) A-I      intronic chr12:110440245(+) A-I      intronic chr12:110440290(+) A-I      intronic chr12:110440310(+) A-I      intronic chr12:110441760(+) A-I      intronic chr12:110441785(+) A-I      intronic chr12:110441848(+) A-I      intronic chr12:110442171(+) A-I      intronic chr12:110442226(+) A-I      intronic chr12:110442239(+) A-I      intronic chr12:110442263(+) A-I      intronic chr12:110442265(+) A-I      intronic chr12:110443046(+) A-I      intronic chr12:110443072(+) A-I      intronic chr12:110443073(+) A-I      intronic chr12:110443174(+) A-I      intronic chr12:110444458(+) A-I      intronic chr12:110444482(+) A-I      intronic chr12:110444501(+) A-I      intronic chr12:110444506(+) A-I      intronic chr12:110444531(+) A-I      intronic chr12:110464013(+) A-I      intronic chr12:110444541(+) A-I      intronic chr12:110444543(+) A-I      intronic chr12:110444663(+) A-I      intronic chr12:110451449(+) A-I      intronic chr12:110445250(+) A-I      intronic chr12:110445279(+) A-I      intronic chr12:110445286(+) A-I      intronic chr12:110446465(+) A-I      intronic chr12:110446511(+) A-I      intronic chr12:110447016(+) A-I      intronic chr12:110464177(+) A-I      intronic chr12:110446519(+) A-I      intronic chr12:110446570(+) A-I      intronic chr12:110446631(+) A-I      intronic chr12:110446910(+) A-I      intronic chr12:110446950(+) A-I      intronic chr12:110446961(+) A-I      intronic chr12:110446964(+) A-I      intronic chr12:110446986(+) A-I      intronic chr12:110446987(+) A-I      intronic chr12:110447026(+) A-I      intronic chr12:110447066(+) A-I      intronic chr12:110447069(+) A-I      intronic chr12:110447095(+) A-I      intronic chr12:110447125(+) A-I      intronic chr12:110451349(+) A-I      intronic chr12:110451369(+) A-I      intronic chr12:110448854(+) A-I      intronic chr12:110451501(+) A-I      intronic chr12:110443198(+) A-I      intronic chr12:110451504(+) A-I      intronic chr12:110451963(+) A-I      intronic chr12:110451998(+) A-I      intronic chr12:110452030(+) A-I      intronic chr12:110452040(+) A-I      intronic chr12:110452055(+) A-I      intronic chr12:110452063(+) A-I      intronic chr12:110463990(+) A-I      intronic chr12:110452067(+) A-I      intronic chr12:110452096(+) A-I      intronic chr12:110451455(+) A-I      intronic chr12:110464599(+) A-I      intronic chr12:110443089(+) A-I      intronic chr12:110452102(+) A-I      intronic chr12:110468868(+) A-I      intronic chr12:110452174(+) A-I      intronic chr12:110454761(+) A-I      intronic chr12:110453456(+) A-I      intronic chr12:110463977(+) A-I      intronic chr12:110463828(+) A-I      intronic chr12:110452182(+) A-I      intronic chr12:110463906(+) A-I      intronic chr12:110453518(+) A-I      intronic chr12:110453549(+) A-I      intronic chr12:110453561(+) A-I      intronic chr12:110453869(+) A-I      intronic chr12:110463786(+) A-I      intronic chr12:110463791(+) A-I      intronic chr12:110463806(+) A-I      intronic chr12:110463841(+) A-I      intronic chr12:110463871(+) A-I      intronic chr12:110463951(+) A-I      intronic chr12:110464203(+) A-I      intronic chr12:110464608(+) A-I      intronic chr12:110464510(+) A-I      intronic chr12:110473574(+) A-I      intronic chr12:110441842(+) A-I      intronic chr12:110447147(+) A-I      intronic chr12:110464511(+) A-I      intronic chr12:110453485(+) A-I      intronic chr12:110446951(+) A-I      intronic chr12:110463866(+) A-I      intronic chr12:110454678(+) A-I      intronic chr12:110446528(+) A-I      intronic chr12:110464516(+) A-I      intronic chr12:110439314(+) A-I      intronic chr12:110443047(+) A-I      intronic chr12:110439460(+) A-I      intronic chr12:110441843(+) A-I      intronic chr12:110468742(+) A-I      intronic chr12:110442166(+) A-I      intronic chr12:110455687(+) A-I      intronic chr12:110448825(+) A-I      intronic chr12:110454717(+) A-I      intronic chr12:110473551(+) A-I      intronic chr12:110468744(+) A-I      intronic chr12:110464310(+) A-I      intronic chr12:110440261(+) A-I      intronic chr12:110473700(+) A-I      intronic chr12:110473438(+) A-I      intronic chr12:110464208(+) A-I      intronic chr12:110451320(+) A-I      intronic chr12:110443197(+) A-I      intronic chr12:110460270(+) A-I      intronic chr12:110454658(+) A-I      intronic chr12:110441776(+) A-I      intronic chr12:110464189(+) A-I      intronic chr12:110469391(+) A-I      intronic chr12:110469390(+) A-I      intronic chr12:110441761(+) A-I      intronic chr12:110443050(+) A-I      intronic chr12:110463810(+) A-I      intronic chr12:110464425(+) A-I      intronic chr12:110441872(+) A-I      intronic chr12:110443150(+) A-I      intronic chr12:110439426(+) A-I      intronic chr12:110464454(+) A-I      intronic chr12:110451442(+) A-I      intronic chr12:110469339(+) A-I      intronic chr12:110443204(+) A-I      intronic chr12:110455643(+) A-I      intronic chr12:110438693(+) A-I      intronic chr12:110464525(+) A-I      intronic chr12:110448799(+) A-I      intronic chr12:110469293(+) A-I      intronic chr12:110446530(+) A-I      intronic chr12:110443210(+) A-I      intronic chr12:110448802(+) A-I      intronic chr12:110473476(+) A-I      intronic chr12:110473704(+) A-I      intronic chr12:110455536(+) A-I      intronic chr12:110440221(+) A-I      intronic chr12:110464531(+) A-I      intronic chr12:110446653(+) A-I      intronic chr12:110464334(+) A-I      intronic chr12:110444601(+) A-I      intronic chr12:110439487(+) A-I      intronic chr12:110473623(+) A-I      intronic chr12:110463909(+) A-I      intronic chr12:110464526(+) A-I      intronic chr12:110454695(+) A-I      intronic chr12:110473228(+) A-I      intronic chr12:110454671(+) A-I      intronic chr12:110468738(+) A-I      intronic chr12:110446605(+) A-I      intronic chr12:110444684(+) A-I      intronic chr12:110446525(+) A-I      intronic chr12:110464288(+) A-I      intronic chr12:110443080(+) A-I      intronic chr12:110439847(+) A-I      intronic chr12:110473579(+) A-I      intronic chr12:110468789(+) A-I      intronic chr12:110464576(+) A-I      intronic chr12:110462932(+) A-I      intronic chr12:110473607(+) A-I      intronic chr12:110464303(+) A-I      intronic chr12:110453376(+) A-I      intronic chr12:110464124(+) A-I      intronic chr12:110446990(+) A-I      intronic chr12:110473683(+) A-I      intronic chr12:110464284(+) A-I      intronic chr12:110443112(+) A-I      intronic chr12:110439806(+) A-I      intronic chr12:110464130(+) A-I      intronic chr12:110473155(+) A-I      intronic chr12:110472280(+) A-I      intronic chr12:110463942(+) A-I      intronic chr12:110463867(+) A-I      intronic chr12:110473435(+) A-I      intronic chr12:110442978(+) A-I      intronic chr12:110463948(+) A-I      intronic chr12:110455456(+) A-I      intronic chr12:110464032(+) A-I      intronic chr12:110469295(+) A-I      intronic chr12:110441714(+) A-I      intronic chr12:110442165(+) A-I      intronic chr12:110441816(+) A-I      intronic chr12:110453911(+) A-I      intronic chr12:110443093(+) A-I      intronic chr12:110446905(+) A-I      intronic chr12:110447726(+) A-I      intronic chr12:110439820(+) A-I      intronic chr12:110454784(+) A-I      intronic chr12:110441803(+) A-I      intronic chr12:110439472(+) A-I      intronic chr12:110444584(+) A-I      intronic chr12:110443059(+) A-I      intronic chr12:110440197(+) A-I      intronic chr12:110455562(+) A-I      intronic chr12:110455483(+) A-I      intronic chr12:110451962(+) A-I      intronic chr12:110453552(+) A-I      intronic chr12:110448851(+) A-I      intronic chr12:110454015(+) A-I      intronic chr12:110455638(+) A-I      intronic chr12:110453452(+) A-I      intronic chr12:110464173(+) A-I      intronic chr12:110454977(+) A-I      intronic chr12:110464637(+) A-I      intronic chr12:110442976(+) A-I      intronic chr12:110451960(+) A-I      intronic chr12:110464217(+) A-I      intronic chr12:110444479(+) A-I      intronic chr12:110464639(+) A-I      intronic chr12:110464225(+) A-I      intronic chr12:110464046(+) A-I      intronic chr12:110445249(+) A-I      intronic chr12:110455484(+) A-I      intronic chr12:110446991(+) A-I      intronic chr12:110442273(+) A-I      intronic chr12:110439464(+) A-I      intronic chr12:110446531(+) A-I      intronic chr12:110442980(+) A-I      intronic chr12:110451429(+) A-I      intronic chr12:110441802(+) A-I      intronic chr12:110468714(+) A-I      intronic chr12:110464529(+) A-I      intronic chr12:110440246(+) A-I      intronic chr12:110441248(+) A-I      intronic chr12:110446480(+) A-I      intronic chr12:110455463(+) A-I      intronic chr12:110443051(+) A-I      intronic chr12:110441801(+) A-I      intronic chr12:110469273(+) A-I      intronic chr12:110446967(+) A-I      intronic chr12:110473152(+) A-I      intronic chr12:110472359(+) A-I      intronic chr12:110453614(+) A-I      intronic chr12:110440370(+) A-I      intronic chr12:110453874(+) A-I      intronic chr12:110446488(+) A-I      intronic chr12:110446470(+) A-I      intronic chr12:110441780(+) A-I      intronic chr12:110439362(+) A-I      intronic chr12:110464123(+) A-I      intronic chr12:110464129(+) A-I      intronic chr12:110464372(+) A-I      intronic chr12:110464262(+) A-I      intronic chr12:110443133(+) A-I      intronic chr12:110442385(+) A-I      intronic chr12:110469257(+) A-I      intronic chr12:110443205(+) A-I      intronic chr12:110439418(+) A-I      intronic chr12:110455514(+) A-I      intronic chr12:110473172(+) A-I      intronic chr12:110441708(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ANKRD13A	chr12:110464525(+) A-I intron -    22327324 chr12:110439820(+) A-I intron -    21960545 chr12:110442978(+) A-I intron -    21960545 chr12:110442980(+) A-I intron -    21960545 chr12:110443089(+) A-I intron -    21960545 chr12:110443093(+) A-I intron -    21960545 chr12:110443133(+) A-I intron -    21960545 chr12:110443150(+) A-I intron -    21960545 chr12:110445325(+) A-I intron -    21960545 chr12:110451320(+) A-I intron -    21960545 chr12:110451322(+) A-I intron -    21960545 chr12:110453376(+) A-I intron -    21960545 chr12:110453416(+) A-I intron -    21960545 chr12:110453911(+) A-I intron -    21960545 chr12:110472280(+) A-I intron -    21960545 chr12:110472328(+) A-I intron -    21960545 chr12:110472367(+) A-I intron -    21960545 chr12:110458924(+) T-G intron -    21725310 chr12:110439362(+) A-G intron -    22484847 chr12:110443089(+) A-G intron -    22484847 chr12:110443198(+) A-G intron -    22484847 chr12:110446470(+) A-G intron -    22484847 chr12:110446528(+) A-G intron -    22484847 chr12:110448825(+) A-G intron -    22484847 chr12:110448851(+) A-G intron -    22484847 chr12:110448854(+) A-G intron -    22484847 chr12:110454601(+) A-G intron -    22484847 chr12:110454695(+) A-G intron -    22484847 chr12:110454717(+) A-G intron -    22484847 chr12:110455545(+) C-T intron -    22484847 chr12:110459292(+) A-G intron -    22484847 chr12:110459376(+) A-G intron -    22484847 chr12:110459492(+) A-G intron -    22484847 chr12:110459504(+) A-G intron -    22484847 chr12:110460107(+) A-G intron -    22484847 chr12:110460111(+) A-G intron -    22484847 chr12:110460211(+) A-G intron -    22484847 chr12:110464177(+) A-G intron -    22484847 chr12:110464217(+) A-G intron -    22484847 chr12:110464525(+) A-G intron -    22484847 chr12:110473579(+) A-G intron -    22484847 chr12:110455456(+) A-G intron -    22484847 chr12:110438580(+) G-T intron -    22484847 chr12:110439314(+) A-G intron -    22484847 chr12:110439418(+) A-G intron -    22484847 chr12:110439460(+) A-G intron -    22484847 chr12:110439472(+) A-G intron -    22484847 chr12:110439820(+) A-G intron -    22484847 chr12:110440197(+) A-G intron -    22484847 chr12:110440246(+) A-G intron -    22484847 chr12:110440320(+) T-C intron -    22484847 chr12:110440370(+) A-G intron -    22484847 chr12:110441714(+) A-G intron -    22484847 chr12:110441776(+) A-G intron -    22484847 chr12:110441780(+) A-G intron -    22484847 chr12:110441816(+) A-G intron -    22484847 chr12:110442165(+) A-G intron -    22484847 chr12:110442166(+) A-G intron -    22484847 chr12:110442273(+) A-G intron -    22484847 chr12:110442976(+) A-G intron -    22484847 chr12:110442978(+) A-G intron -    22484847 chr12:110442980(+) A-G intron -    22484847 chr12:110443047(+) A-G intron -    22484847 chr12:110443050(+) A-G intron -    22484847 chr12:110443051(+) A-G intron -    22484847 chr12:110443059(+) A-G intron -    22484847 chr12:110443080(+) A-G intron -    22484847 chr12:110443093(+) A-G intron -    22484847 chr12:110443133(+) A-G intron -    22484847 chr12:110443150(+) A-G intron -    22484847 chr12:110443197(+) A-G intron -    22484847 chr12:110443204(+) A-G intron -    22484847 chr12:110443205(+) A-G intron -    22484847 chr12:110443210(+) A-G intron -    22484847 chr12:110444479(+) A-G intron -    22484847 chr12:110444505(+) A-G intron -    22484847 chr12:110444601(+) A-G intron -    22484847 chr12:110445249(+) A-G intron -    22484847 chr12:110446479(+) T-C intron -    22484847 chr12:110446480(+) A-G intron -    22484847 chr12:110446488(+) A-G intron -    22484847 chr12:110446525(+) A-G intron -    22484847 chr12:110446605(+) A-G intron -    22484847 chr12:110446951(+) A-G intron -    22484847 chr12:110446967(+) A-G intron -    22484847 chr12:110446990(+) A-G intron -    22484847 chr12:110446991(+) A-G intron -    22484847 chr12:110447726(+) A-G intron -    22484847 chr12:110448799(+) A-G intron -    22484847 chr12:110448802(+) A-G intron -    22484847 chr12:110451320(+) A-G intron -    22484847 chr12:110451442(+) A-G intron -    22484847 chr12:110451455(+) A-G intron -    22484847 chr12:110451960(+) A-G intron -    22484847 chr12:110451962(+) A-G intron -    22484847 chr12:110453445(+) A-G intron -    22484847 chr12:110453485(+) A-G intron -    22484847 chr12:110453552(+) A-G intron -    22484847 chr12:110453554(+) A-G intron -    22484847 chr12:110454015(+) A-G intron -    22484847 chr12:110454784(+) A-G intron -    22484847 chr12:110455004(+) T-C intron -    22484847 chr12:110455638(+) A-G intron -    22484847 chr12:110455643(+) A-G intron -    22484847 chr12:110459343(+) A-G intron -    22484847 chr12:110459360(+) A-G intron -    22484847 chr12:110459392(+) A-G intron -    22484847 chr12:110463866(+) A-G intron -    22484847 chr12:110463867(+) A-G intron -    22484847 chr12:110463884(+) A-G intron -    22484847 chr12:110463942(+) A-G intron -    22484847 chr12:110463948(+) A-G intron -    22484847 chr12:110463977(+) A-G intron -    22484847 chr12:110464044(+) A-G intron -    22484847 chr12:110464123(+) A-G intron -    22484847 chr12:110464124(+) A-G intron -    22484847 chr12:110464129(+) A-G intron -    22484847 chr12:110464173(+) A-G intron -    22484847 chr12:110464208(+) A-G intron -    22484847 chr12:110464227(+) A-G intron -    22484847 chr12:110464284(+) A-G intron -    22484847 chr12:110464334(+) A-G intron -    22484847 chr12:110468738(+) A-G intron -    22484847 chr12:110468789(+) A-G intron -    22484847 chr12:110469341(+) A-G intron -    22484847 chr12:110469390(+) A-G intron -    22484847 chr12:110469391(+) A-G intron -    22484847 chr12:110473438(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ANKRD13A	chr12:110437330-110437331(+) m6A 5'UTR//exon//intron       24209618 chr12:110465991-110465992(+) m6A exon//intron       27773535 chr12:110465999-110466000(+) m6A exon//intron       27773535 chr12:110466008-110466009(+) m6A exon//intron       24981863//27773535 chr12:110466204-110466205(+) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr12:110466242-110466243(+) m6A exon//intron       24284625//25456834//24981863//27773535//27371828//22608085 chr12:110466272-110466273(+) m6A exon//intron       24284625//24981863//27773535//27371828//22608085 chr12:110466317-110466318(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535 chr12:110466344-110466345(+) m6A 3'UTR//CDS//exon       24284625 chr12:110466414-110466415(+) Am 3'UTR//CDS//exon       - chr12:110474067-110474068(+) m6A CDS//exon//intron       - chr12:110474076-110474077(+) m6A CDS//exon//intron       - chr12:110474104-110474105(+) m6A CDS//exon//intron       - chr12:110475359-110475360(+) m6A 3'UTR//exon       24284625//24981863 chr12:110475504-110475505(+) m6A 3'UTR//exon       24981863 chr12:110475511-110475512(+) m6A 3'UTR//exon       24981863 chr12:110475553-110475554(+) m6A 3'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-3p	Exosome K562 cells     24460325
	ANKRD13A	Chromatin K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-3p
Interactor2: ANKRD13A

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).