Basic Information:

  VIRBase ID:  

VHID00285032

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-3p:  MIMAT0000997          DAZAP1:  NM_170711     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-3p	DAZAP1
miRBase Accession/Entrez ID	MIMAT0000997	26528
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DAZAP1	chr19:1414334(+) A-I      intronic chr19:1427037(+) A-I      intronic chr19:1413629(+) A-I      intronic chr19:1414499(+) A-I      intronic chr19:1414567(+) A-I      intronic chr19:1414584(+) A-I      intronic chr19:1414597(+) A-I      intronic chr19:1414685(+) A-I      intronic chr19:1414687(+) A-I      intronic chr19:1414118(+) A-I      intronic chr19:1414217(+) A-I      intronic chr19:1414919(+) A-I      intronic chr19:1414873(+) A-I      intronic chr19:1414956(+) A-I      intronic chr19:1414094(+) A-I      intronic chr19:1414264(+) A-I      intronic chr19:1414535(+) A-I      intronic chr19:1414239(+) A-I      intronic chr19:1414568(+) A-I      intronic chr19:1414269(+) A-I      intronic chr19:1414089(+) A-I      intronic chr19:1414886(+) A-I      intronic chr19:1414878(+) A-I      intronic chr19:1414620(+) A-I      intronic chr19:1414921(+) A-I      intronic chr19:1414279(+) A-I      intronic chr19:1414937(+) A-I      intronic chr19:1414182(+) A-I      intronic chr19:1431390(+) A-I      intronic chr19:1414585(+) A-I      intronic chr19:1414946(+) A-I      intronic chr19:1414200(+) A-I      intronic chr19:1414624(+) A-I      intronic chr19:1413689(+) A-I      intronic chr19:1414698(+) A-I      intronic chr19:1414134(+) A-I      intronic chr19:1414095(+) A-I      intronic chr19:1414882(+) A-I      intronic chr19:1414887(+) A-I      intronic chr19:1414920(+) A-I      intronic chr19:1414197(+) A-I      intronic chr19:1414582(+) A-I      intronic chr19:1414070(+) A-I      intronic chr19:1414278(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DAZAP1	chr19:1413703(+) A-G intron -    22484847 chr19:1414046(+) A-G intron -    22484847 chr19:1414089(+) A-G intron -    22484847 chr19:1414095(+) A-G intron -    22484847 chr19:1414239(+) A-G intron -    22484847 chr19:1414269(+) A-G intron -    22484847 chr19:1414278(+) A-G intron -    22484847 chr19:1414279(+) A-G intron -    22484847 chr19:1414535(+) A-G intron -    22484847 chr19:1414568(+) A-G intron -    22484847 chr19:1414582(+) A-G intron -    22484847 chr19:1414585(+) A-G intron -    22484847 chr19:1414614(+) A-G intron -    22484847 chr19:1414624(+) A-G intron -    22484847 chr19:1414698(+) A-G intron -    22484847 chr19:1414878(+) A-G intron -    22484847 chr19:1414887(+) A-G intron -    22484847 chr19:1414945(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DAZAP1	chr19:1407776-1407777(+) m6A CDS//exon       24284625//24209618//22575960 chr19:1407793-1407794(+) Gm CDS//exon       - chr19:1412993-1412994(+) Cm intron       - chr19:1417420-1417421(+) m6A exon//intron       24209618 chr19:1418204-1418205(+) m6A CDS//exon       24209618 chr19:1418267-1418268(+) m6A CDS//exon       24209618 chr19:1418310-1418311(+) m6A CDS//exon       24209618//27773535//22575960 chr19:1418316-1418317(+) m6A CDS//exon       24209618//27773535//22575960 chr19:1418344-1418345(+) m6A CDS//exon       24209618//27773535//22575960 chr19:1418709-1418710(+) m6A CDS//exon//intron       24209618//27773535//22575960 chr19:1421154-1421155(+) m6A CDS//exon       24209618//27773535//22575960 chr19:1421221-1421222(+) m6A CDS//exon       24209618//27773535 chr19:1421245-1421246(+) Am CDS//exon       - chr19:1425904-1425905(+) m6A CDS//intron       24209618 chr19:1425915-1425916(+) m6A CDS//intron       24209618 chr19:1426364-1426365(+) m6A exon//intron       24209618 chr19:1426410-1426411(+) m6A exon//intron       24284625 chr19:1426422-1426423(+) m6A exon//intron       24284625 chr19:1426560-1426561(+) m6A exon//intron       - chr19:1428133-1428134(+) Tm exon//intron       - chr19:1428800-1428801(+) m6A exon//intron       - chr19:1428819-1428820(+) m6A exon//intron       - chr19:1428868-1428869(+) m6A CDS//exon       - chr19:1428890-1428891(+) m6A CDS//exon       22575960 chr19:1429984-1429985(+) m6A CDS//exon       24284625//22575960 chr19:1430230-1430231(+) m6A CDS//exon       24284625//22575960 chr19:1432150-1432151(+) m6A exon//intron       24284625 chr19:1432638-1432639(+) m6A CDS//exon       24284625//22575960 chr19:1432668-1432669(+) m6A CDS//exon       24284625 chr19:1432731-1432732(+) m6A exon//intron       24284625 chr19:1434626-1434627(+) m6A exon//intron       - chr19:1434634-1434635(+) m6A exon//intron       - chr19:1434702-1434703(+) m6A exon//intron       24209618 chr19:1434721-1434722(+) m6A exon//intron       24284625//24209618 chr19:1434750-1434751(+) m6A 3'UTR//CDS//exon       24284625//24209618 chr19:1434766-1434767(+) m6A 3'UTR//CDS//exon       24284625//24209618//22575960 chr19:1434780-1434781(+) m6A 3'UTR//CDS//exon       24284625//24209618//22575960 chr19:1434873-1434874(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22575960 chr19:1434891-1434892(+) Y 3'UTR//CDS//exon       26075521 chr19:1434942-1434943(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//22575960 chr19:1434956-1434957(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//22575960 chr19:1434964-1434965(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//22575960 chr19:1434981-1434982(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr19:1435068-1435069(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr19:1435173-1435174(+) m6A 3'UTR//exon       24209618 chr19:1435526-1435527(+) m6A 3'UTR//exon       25456834 chr19:1435575-1435576(+) m6A 3'UTR//exon       25456834 chr19:1435580-1435581(+) m6A 3'UTR//exon       25456834 chr19:1435682-1435683(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-3p	Exosome K562 cells     24460325
	DAZAP1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-3p
Interactor2: DAZAP1

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	PARalyzer
Support Database	ViRBase//VIRmiRNA

References:

PMID	22291592	Target region	CDS
Source	ViRBase//VIRmiRNA	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).