Basic Information:

  VIRBase ID:  

VHID00284916

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-3p:  MIMAT0000997          MKRN2:  NM_014160     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-3p	MKRN2
miRBase Accession/Entrez ID	MIMAT0000997	23609
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HSPC070//RNF62

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MKRN2	chr3:12614358(+) A-I      intronic chr3:12614791(+) A-I      intronic chr3:12614163(+) A-I      intronic chr3:12614200(+) A-I      intronic chr3:12614281(+) A-I      intronic chr3:12612709(+) A-I      intronic chr3:12605063(+) A-I      intronic chr3:12605068(+) A-I      intronic chr3:12612776(+) A-I      intronic chr3:12605128(+) A-I      intronic chr3:12614206(+) A-I      intronic chr3:12614223(+) A-I      intronic chr3:12614777(+) A-I      intronic chr3:12609082(+) A-I      intronic chr3:12612261(+) A-I      intronic chr3:12614769(+) A-I      intronic chr3:12615503(+) A-I      intronic chr3:12614147(+) A-I      intronic chr3:12605118(+) A-I      intronic chr3:12622075(+) A-I      intronic chr3:12621345(+) A-I      intronic chr3:12621977(+) A-I      intronic chr3:12621322(+) A-I      intronic chr3:12615298(+) A-I      intronic chr3:12615271(+) A-I      intronic chr3:12614965(+) A-I      intronic chr3:12614136(+) A-I      intronic chr3:12620909(+) A-I      intronic chr3:12615277(+) A-I      intronic chr3:12614845(+) A-I      intronic chr3:12621384(+) A-I      intronic chr3:12614233(+) A-I      intronic chr3:12612118(+) A-I      intronic chr3:12612784(+) A-I      intronic chr3:12614182(+) A-I      intronic chr3:12612710(+) A-I      intronic chr3:12612771(+) A-I      intronic chr3:12614213(+) A-I      intronic chr3:12615344(+) A-I      intronic chr3:12615337(+) A-I      intronic chr3:12614768(+) A-I      intronic chr3:12621328(+) A-I      intronic chr3:12620849(+) A-I      intronic chr3:12614284(+) A-I      intronic chr3:12615138(+) A-I      intronic chr3:12605674(+) A-I      intronic chr3:12615473(+) A-I      intronic chr3:12609707(+) A-I      intronic chr3:12607435(+) A-I      intronic chr3:12620934(+) A-I      intronic chr3:12615312(+) A-I      intronic chr3:12615485(+) A-I      intronic chr3:12614157(+) A-I      intronic chr3:12621350(+) A-I      intronic chr3:12612739(+) A-I      intronic chr3:12612294(+) A-I      intronic chr3:12621385(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MKRN2	chr3:12605633(+) T-C intron -    22484847 chr3:12605674(+) A-G intron -    22484847 chr3:12612118(+) A-G intron -    22484847 chr3:12612403(+) G-A intron -    22484847 chr3:12612710(+) A-G intron -    22484847 chr3:12612739(+) A-G intron -    22484847 chr3:12612771(+) A-G intron -    22484847 chr3:12612775(+) A-G intron -    22484847 chr3:12614136(+) A-G intron -    22484847 chr3:12614157(+) A-G intron -    22484847 chr3:12614182(+) A-G intron -    22484847 chr3:12614213(+) A-G intron -    22484847 chr3:12614233(+) A-G intron -    22484847 chr3:12614284(+) A-G intron -    22484847 chr3:12614845(+) A-G intron -    22484847 chr3:12615138(+) A-G intron -    22484847 chr3:12615271(+) A-G intron -    22484847 chr3:12615277(+) A-G intron -    22484847 chr3:12615281(+) A-G intron -    22484847 chr3:12620900(+) A-G intron -    22484847 chr3:12620909(+) A-G intron -    22484847 chr3:12620934(+) A-G intron -    22484847 chr3:12621322(+) A-G intron -    22484847 chr3:12621384(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MKRN2	chr3:12610435-12610436(+) m6A CDS//intron       - chr3:12610442-12610443(+) m6A CDS//intron       - chr3:12623745-12623746(+) m6A CDS       24284625//24981863 chr3:12623794-12623795(+) m6A 3'UTR       24284625//24981863 chr3:12624019-12624020(+) m6A 3'UTR       24284625 chr3:12624027-12624028(+) m6A 3'UTR       24284625 chr3:12624053-12624054(+) m6A 3'UTR       24284625 chr3:12624237-12624238(+) m6A 3'UTR       27773535 chr3:12624276-12624277(+) m6A 3'UTR       27773535 chr3:12625038-12625039(+) m6A 3'UTR       27773535 chr3:12625145-12625146(+) m6A 3'UTR       27773535 chr3:12625182-12625183(+) m6A 3'UTR       27773535 chr3:12625193-12625194(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-3p	Exosome K562 cells     24460325
	MKRN2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-3p
Interactor2: MKRN2

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg