Basic Information:

  VIRBase ID:  

VHID00283387

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-3p:  MIMAT0000997          EYA4:  NM_001301013     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-3p	EYA4
miRBase Accession/Entrez ID	MIMAT0000997	2070
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CMD1J//DFNA10

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EYA4	chr6:133658209(+) A-I      intronic chr6:133658207(+) A-I      intronic chr6:133659168(+) A-I      intronic chr6:133621753(+) A-I      intronic chr6:133614957(+) A-I      intronic chr6:133621722(+) A-I      intronic chr6:133605406(+) A-I      intronic chr6:133615845(+) A-I      intronic chr6:133832998(+) A-I      intronic chr6:133615806(+) A-I      intronic chr6:133615726(+) A-I      intronic chr6:133588701(+) A-I      intronic chr6:133706420(+) A-I      intronic chr6:133620683(+) A-I      intronic chr6:133588600(+) A-I      intronic chr6:133590172(+) A-I      intronic chr6:133590213(+) A-I      intronic chr6:133588593(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EYA4	chr6:133561834-133561835(+) m6A 5'UTR       22608085 chr6:133562499-133562500(+) m6A 5'UTR//intron       24981863//22608085 chr6:133562836-133562837(+) m6A 5'UTR//exon       24981863 chr6:133562848-133562849(+) m6A 5'UTR//exon       24981863 chr6:133562863-133562864(+) m6A 5'UTR//exon       24981863 chr6:133562874-133562875(+) m6A 5'UTR//exon       24981863 chr6:133566247-133566248(+) m6A exon//intron       24981863 chr6:133566254-133566255(+) m6A exon//intron       24981863 chr6:133594087-133594088(+) Y intron       16381836 chr6:133594089-133594090(+) Y intron       16381836 chr6:133665336-133665337(+) Gm intron       - chr6:133802682-133802683(+) Cm CDS//exon       - chr6:133846376-133846377(+) m6A CDS//intron       24981863//22608085 chr6:133849899-133849900(+) m6A CDS//intron       24284625//24981863//22608085 chr6:133850108-133850109(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr6:133850130-133850131(+) m6A 3'UTR//intron       24284625//24981863//26404942//22575960//22608085 chr6:133850213-133850214(+) m6A 3'UTR//intron       24284625//24981863//26404942//22575960//22608085 chr6:133850239-133850240(+) m6A 3'UTR//intron       24284625//24981863//26404942//27773535//22575960//22608085 chr6:133850388-133850389(+) m6A 3'UTR//intron       24284625//24981863//26404942//22575960//22608085 chr6:133850399-133850400(+) m6A 3'UTR//intron       24284625//24981863//26404942//22575960//22608085 chr6:133850413-133850414(+) m6A 3'UTR//intron       24284625//24981863//26404942//22608085 chr6:133850888-133850889(+) m6A 3'UTR//intron       24981863 chr6:133850896-133850897(+) m6A 3'UTR//intron       24981863 chr6:133850964-133850965(+) m6A 3'UTR//intron       24981863 chr6:133852389-133852390(+) m6A 3'UTR       24981863 chr6:133852468-133852469(+) m6A 3'UTR       24284625//24981863 chr6:133852474-133852475(+) m6A 3'UTR       24284625//24981863 chr6:133852535-133852536(+) m6A 3'UTR       24284625//24981863 chr6:133852540-133852541(+) m6A 3'UTR       24284625//24981863 chr6:133852551-133852552(+) m6A 3'UTR       24284625//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-3p	Exosome K562 cells     24460325
	EYA4	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-3p
Interactor2: EYA4

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg