Detail Information

Basic Information:


  VIRBase ID:  

VHID00282814

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:           FBXO33:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BHRF1-2-5p FBXO33
miRBase
Accession/Entrez ID		 MIMAT0000996 254170
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - BMND12//c14_5247//Fbx33

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FBXO33
chr14:39873700(-) A-I      intronic
chr14:39873699(-) A-I      intronic
chr14:39889702(-) A-I      intronic
chr14:39873695(-) A-I      intronic
chr14:39873687(-) A-I      intronic
chr14:39897043(-) A-I      intronic
chr14:39873639(-) A-I      intronic
chr14:39885041(-) A-I      intronic
chr14:39873711(-) A-I      intronic
chr14:39885122(-) A-I      intronic
chr14:39872068(-) A-I      intronic
chr14:39897146(-) A-I      intronic
chr14:39873705(-) A-I      intronic
chr14:39874109(-) A-I      intronic
chr14:39874276(-) A-I      intronic
chr14:39873759(-) A-I      intronic
chr14:39897502(-) A-I      intronic
chr14:39897534(-) A-I      intronic
chr14:39897578(-) A-I      intronic
chr14:39885135(-) A-I      intronic
chr14:39873703(-) A-I      intronic
chr14:39885035(-) A-I      intronic
chr14:39897628(-) A-I      intronic
chr14:39873702(-) A-I      intronic
chr14:39874324(-) A-I      intronic
chr14:39896900(-) A-I      intronic
chr14:39874185(-) A-I      intronic
chr14:39887396(-) A-I      intronic
chr14:39874265(-) A-I      intronic
chr14:39887416(-) A-I      intronic
chr14:39885150(-) A-I      intronic
chr14:39887457(-) A-I      intronic
chr14:39885022(-) A-I      intronic
chr14:39897547(-) A-I      intronic
chr14:39873802(-) A-I      intronic
chr14:39897068(-) A-I      intronic
chr14:39873216(-) A-I      intronic
chr14:39874118(-) A-I      intronic
chr14:39897036(-) A-I      intronic
chr14:39885144(-) A-I      intronic
chr14:39874314(-) A-I      intronic
chr14:39880397(-) A-I      intronic
chr14:39897142(-) A-I      intronic
chr14:39885044(-) A-I      intronic
chr14:39897636(-) A-I      intronic
chr14:39878058(-) A-I      intronic
chr14:39897095(-) A-I      intronic
chr14:39874096(-) A-I      intronic
chr14:39896926(-) A-I      intronic
chr14:39872051(-) A-I      intronic
chr14:39887446(-) A-I      intronic
chr14:39874244(-) A-I      intronic
chr14:39884498(-) A-I      intronic
chr14:39887447(-) A-I      intronic
chr14:39887540(-) A-I      intronic
chr14:39891449(-) A-I      intronic
chr14:39874240(-) A-I      intronic
chr14:39874108(-) A-I      intronic
chr14:39874146(-) A-I      intronic
chr14:39897506(-) A-I      intronic
chr14:39889848(-) A-I      intronic
chr14:39889743(-) A-I      intronic
chr14:39874243(-) A-I      intronic
chr14:39887892(-) A-I      intronic
chr14:39883944(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FBXO33
chr14:39874244(-) A-G intron -    22484847
chr14:39874276(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FBXO33
chr14:39867607-39867608(-) m6A 3'UTR       24981863//22608085
chr14:39867658-39867659(-) m6A 3'UTR       22608085
chr14:39868726-39868727(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:39868770-39868771(-) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//27371828//22608085
chr14:39868798-39868799(-) m6A 3'UTR//CDS       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr14:39868884-39868885(-) m6A 3'UTR//CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:39870608-39870609(-) m6A CDS//intron       24284625//27773535//22608085
chr14:39870720-39870721(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr14:39870872-39870873(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:39870915-39870916(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:39871606-39871607(-) m6A CDS//intron       24284625
chr14:39871628-39871629(-) m6A CDS//intron       24284625
chr14:39871685-39871686(-) m6A CDS//intron       -
chr14:39871712-39871713(-) m6A CDS//intron       -
chr14:39900773-39900774(-) m6A CDS       -
chr14:39900876-39900877(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39900884-39900885(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39900926-39900927(-) m6A CDS       25456834//27371828//27773536//22608085
chr14:39901317-39901318(-) m6A CDS//intron       27773536
chr14:39901647-39901648(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BHRF1-2-5p
Exosome B cell line (Raji)     21505438
FBXO33
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: FBXO33

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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