Detail Information

Basic Information:


  VIRBase ID:  

VHID00282209

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:           PARP9:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BHRF1-2-5p PARP9
miRBase
Accession/Entrez ID		 MIMAT0000996 83666
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - ARTD9//BAL//BAL1//MGC:7868

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PARP9
chr3:122263548(-) A-I      intronic
chr3:122263539(-) A-I      intronic
chr3:122275985(-) A-I      intronic
chr3:122275968(-) A-I      intronic
chr3:122268064(-) A-I      intronic
chr3:122268061(-) A-I      intronic
chr3:122276732(-) A-I      intronic
chr3:122276740(-) A-I      intronic
chr3:122268032(-) A-I      intronic
chr3:122263601(-) A-I      intronic
chr3:122263571(-) A-I      intronic
chr3:122263574(-) A-I      intronic
chr3:122276716(-) A-I      intronic
chr3:122268411(-) A-I      intronic
chr3:122279358(-) A-I      intronic
chr3:122279362(-) A-I      intronic
chr3:122279372(-) A-I      intronic
chr3:122279412(-) A-I      intronic
chr3:122279438(-) A-I      intronic
chr3:122279528(-) A-I      intronic
chr3:122280094(-) A-I      intronic
chr3:122280207(-) A-I      intronic
chr3:122261850(-) A-I      intronic
chr3:122261865(-) A-I      intronic
chr3:122261882(-) A-I      intronic
chr3:122261885(-) A-I      intronic
chr3:122261918(-) A-I      intronic
chr3:122262597(-) A-I      intronic
chr3:122262603(-) A-I      intronic
chr3:122263447(-) A-I      intronic
chr3:122263472(-) A-I      intronic
chr3:122263481(-) A-I      intronic
chr3:122263588(-) A-I      intronic
chr3:122263626(-) A-I      intronic
chr3:122263661(-) A-I      intronic
chr3:122266039(-) A-I      intronic
chr3:122266044(-) A-I      intronic
chr3:122266053(-) A-I      intronic
chr3:122266074(-) A-I      intronic
chr3:122266135(-) A-I      intronic
chr3:122266136(-) A-I      intronic
chr3:122266155(-) A-I      intronic
chr3:122266434(-) A-I      intronic
chr3:122266443(-) A-I      intronic
chr3:122266632(-) A-I      intronic
chr3:122267954(-) A-I      intronic
chr3:122267967(-) A-I      intronic
chr3:122268010(-) A-I      intronic
chr3:122268030(-) A-I      intronic
chr3:122268031(-) A-I      intronic
chr3:122268033(-) A-I      intronic
chr3:122268372(-) A-I      intronic
chr3:122268436(-) A-I      intronic
chr3:122269037(-) A-I      intronic
chr3:122269042(-) A-I      intronic
chr3:122269073(-) A-I      intronic
chr3:122269091(-) A-I      intronic
chr3:122266588(-) A-I      intronic
chr3:122261530(-) A-I      intronic
chr3:122266624(-) A-I      intronic
chr3:122280143(-) A-I      intronic
chr3:122263559(-) A-I      intronic
chr3:122268480(-) A-I      intronic
chr3:122268504(-) A-I      intronic
chr3:122280299(-) A-I      intronic
chr3:122268026(-) A-I      intronic
chr3:122266455(-) A-I      intronic
chr3:122266080(-) A-I      intronic
chr3:122263645(-) A-I      intronic
chr3:122280175(-) A-I      intronic
chr3:122266618(-) A-I      intronic
chr3:122261545(-) A-I      intronic
chr3:122266572(-) A-I      intronic
chr3:122268383(-) A-I      intronic
chr3:122268498(-) A-I      intronic
chr3:122261875(-) A-I      intronic
chr3:122268545(-) A-I      intronic
chr3:122268109(-) A-I      intronic
chr3:122267934(-) A-I      intronic
chr3:122280149(-) A-I      intronic
chr3:122266531(-) A-I      intronic
chr3:122266497(-) A-I      intronic
chr3:122263575(-) A-I      intronic
chr3:122268559(-) A-I      intronic
chr3:122266578(-) A-I      intronic
chr3:122268533(-) A-I      intronic
chr3:122268435(-) A-I      intronic
chr3:122266470(-) A-I      intronic
chr3:122261399(-) A-I      intronic
chr3:122269024(-) A-I      intronic
chr3:122261438(-) A-I      intronic
chr3:122261381(-) A-I      intronic
chr3:122263496(-) A-I      intronic
chr3:122268516(-) A-I      intronic
chr3:122263600(-) A-I      intronic
chr3:122280212(-) A-I      intronic
chr3:122266605(-) A-I      intronic
chr3:122269094(-) A-I      intronic
chr3:122263498(-) A-I      intronic
chr3:122266106(-) A-I      intronic
chr3:122279414(-) A-I      intronic
chr3:122262223(-) A-I      intronic
chr3:122279417(-) A-I      intronic
chr3:122269023(-) A-I      intronic
chr3:122268071(-) A-I      intronic
chr3:122269102(-) A-I      intronic
chr3:122263407(-) A-I      intronic
chr3:122261961(-) A-I      intronic
chr3:122261423(-) A-I      intronic
chr3:122262151(-) A-I      intronic
chr3:122266479(-) A-I      intronic
chr3:122268045(-) A-I      intronic
chr3:122280123(-) A-I      intronic
chr3:122262301(-) A-I      intronic
chr3:122269033(-) A-I      intronic
chr3:122266478(-) A-I      intronic
chr3:122263583(-) A-I      intronic
chr3:122261464(-) A-I      intronic
chr3:122266698(-) A-I      intronic
chr3:122266543(-) A-I      intronic
chr3:122266079(-) A-I      intronic
chr3:122279500(-) A-I      intronic
chr3:122266614(-) A-I      intronic
chr3:122259810(-) A-I      intronic
chr3:122262396(-) A-I      intronic
chr3:122280140(-) A-I      intronic
chr3:122268036(-) A-I      intronic
chr3:122279506(-) A-I      intronic
chr3:122261403(-) A-I      intronic
chr3:122263631(-) A-I      intronic
chr3:122266111(-) A-I      intronic
chr3:122266613(-) A-I      intronic
chr3:122266551(-) A-I      intronic
chr3:122280199(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PARP9
chr3:122268109(-) A-I intron -    15258596
chr3:122268144(-) A-I intron -    15258596
chr3:122268410(-) A-I intron -    15258596
chr3:122275998(-) A-I intron -    22327324
chr3:122275999(-) A-I intron -    22327324
chr3:122276695(-) A-I intron -    22327324
chr3:122276736(-) A-I intron -    22327324
chr3:122276695(-) A-G intron -    22484847
chr3:122276720(-) A-G intron -    22484847
chr3:122276736(-) A-G intron -    22484847
chr3:122276737(-) A-G intron -    22484847
chr3:122261428(-) T-C intron -    22484847
chr3:122261860(-) A-G intron -    22484847
chr3:122261878(-) A-G intron -    22484847
chr3:122263575(-) A-G intron -    22484847
chr3:122263600(-) A-G intron -    22484847
chr3:122263645(-) A-G intron -    22484847
chr3:122266479(-) A-G intron -    22484847
chr3:122266482(-) A-G intron -    22484847
chr3:122266497(-) A-G intron -    22484847
chr3:122266543(-) A-G intron -    22484847
chr3:122266614(-) A-G intron -    22484847
chr3:122266624(-) A-G intron -    22484847
chr3:122268036(-) A-G intron -    22484847
chr3:122268045(-) A-G intron -    22484847
chr3:122268384(-) A-G intron -    22484847
chr3:122268410(-) A-G intron -    22484847
chr3:122268435(-) A-G intron -    22484847
chr3:122269023(-) A-G intron -    22484847
chr3:122269030(-) A-G intron -    22484847
chr3:122269053(-) T-C intron -    22484847
chr3:122269094(-) A-G intron -    22484847
chr3:122269102(-) A-G intron -    22484847
chr3:122279506(-) A-G intron -    22484847
chr3:122280123(-) A-G intron -    22484847
chr3:122280149(-) A-G intron -    22484847
chr3:122280198(-) A-G intron -    22484847
chr3:122280212(-) A-G intron -    22484847
chr3:122275997(-) A-G intron -    22484847
chr3:122275998(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PARP9
chr3:122246987-122246988(-) m6A 3'UTR//exon       24981863//28052920//27773535
chr3:122246998-122246999(-) m6A 3'UTR//exon       24981863//28052920//27773535
chr3:122247075-122247076(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22575960
chr3:122247096-122247097(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22575960
chr3:122247165-122247166(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122247264-122247265(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122247273-122247274(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122247317-122247318(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122247365-122247366(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122247453-122247454(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535
chr3:122247544-122247545(-) m6A CDS//exon       24981863//28052920//27773535
chr3:122247553-122247554(-) m6A CDS//exon       24981863//28052920//27773535
chr3:122250625-122250626(-) m6A 3'UTR//intron       27773535
chr3:122250648-122250649(-) m6A 3'UTR//intron       27773535
chr3:122251699-122251700(-) m6A 3'UTR//intron       27773535
chr3:122251731-122251732(-) m6A 3'UTR//intron       27773535
chr3:122251804-122251805(-) m6A 3'UTR//intron       27773535
chr3:122251909-122251910(-) m6A 3'UTR//intron       24981863//27773535
chr3:122251939-122251940(-) m6A 3'UTR//intron       24981863//27773535
chr3:122251945-122251946(-) m6A 3'UTR//intron       24981863//27773535
chr3:122252082-122252083(-) m6A 3'UTR//intron       27773535
chr3:122253778-122253779(-) m6A 3'UTR//intron       27773535
chr3:122253824-122253825(-) m6A 3'UTR//intron       27773535
chr3:122253833-122253834(-) m6A 3'UTR//intron       27773535
chr3:122253881-122253882(-) m6A 3'UTR//intron       27773535
chr3:122254649-122254650(-) m6A 3'UTR//intron       24981863
chr3:122255175-122255176(-) m6A CDS//exon       27773535
chr3:122255813-122255814(-) m6A CDS//exon       27773535
chr3:122255893-122255894(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122255911-122255912(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122259392-122259393(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122259444-122259445(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122259486-122259487(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122259514-122259515(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122259563-122259564(-) m6A CDS//exon       24284625//24981863//27773535
chr3:122264289-122264290(-) m6A CDS//exon       27773535
chr3:122264397-122264398(-) m6A exon//intron       27773535
chr3:122269540-122269541(-) m6A CDS//intron       27773535
chr3:122269560-122269561(-) m6A CDS//intron       27773535
chr3:122269567-122269568(-) m6A CDS//intron       27773535
chr3:122274178-122274179(-) m6A CDS//intron       24209618//24981863//27773535
chr3:122274209-122274210(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chr3:122274216-122274217(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chr3:122274277-122274278(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr3:122274350-122274351(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr3:122274362-122274363(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr3:122274425-122274426(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr3:122274504-122274505(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr3:122274549-122274550(-) m6A CDS//intron       24284625//24209618//24981863//28052920//27773535//22575960
chr3:122274624-122274625(-) m6A CDS//intron       24284625//24209618//27773535
chr3:122274965-122274966(-) m6A CDS//intron       24981863
chr3:122278462-122278463(-) m6A CDS       24981863//27773535
chr3:122278475-122278476(-) m6A 5'UTR       24981863//27773535
chr3:122278487-122278488(-) m6A 5'UTR       24981863//27773535
chr3:122278497-122278498(-) m6A 5'UTR       24981863//27773535
chr3:122278533-122278534(-) m6A 5'UTR       24981863//27773535
chr3:122282970-122282971(-) m6A 5'UTR//intron       24981863//27773535
chr3:122283324-122283325(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BHRF1-2-5p
Exosome B cell line (Raji)     21505438
PARP9
Exosome Blood     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: PARP9

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region CDS
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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