Basic Information:

  VIRBase ID:  

VHID00282024

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:  MIMAT0000996          TMEM106C:  NM_024056     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-5p	TMEM106C
miRBase Accession/Entrez ID	MIMAT0000996	79022
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMEM106C	chr12:48359487(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMEM106C	chr12:48357699-48357700(+) m6A 5'UTR//intron       24981863 chr12:48357929-48357930(+) m6A exon//intron       - chr12:48357992-48357993(+) m6A 5'UTR//exon//intron       - chr12:48358104-48358105(+) Gm 5'UTR//CDS//exon//intron       - chr12:48358116-48358117(+) m1A 5'UTR//CDS//exon//intron       26863196 chr12:48358187-48358188(+) m6A 5'UTR//CDS//exon//intron       - chr12:48362086-48362087(+) m6A 3'UTR//CDS//exon       24284625//24981863//26404942 chr12:48362142-48362143(+) m6A 3'UTR//exon       24284625//24981863//27773535 chr12:48362167-48362168(+) m6A 3'UTR//exon       24284625//24981863 chr12:48362201-48362202(+) m6A 3'UTR//exon       24284625//24981863 chr12:48362338-48362339(+) m6A 3'UTR       27773535 chr12:48362425-48362426(+) m6A 3'UTR       26404942//27773535 chr12:48362448-48362449(+) m6A 3'UTR       26404942//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-5p	Exosome B cell line (Raji)     21505438
	TMEM106C	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: TMEM106C

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg