Detail Information

Basic Information:


  VIRBase ID:  

VHID00280377

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:           SSR3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BHRF1-2-5p SSR3
miRBase
Accession/Entrez ID		 MIMAT0000996 6747
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - TRAPG

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SSR3
chr3:156259404(-) A-I      3'UTR
chr3:156259371(-) A-I      3'UTR
chr3:156259257(-) A-I      3'UTR
chr3:156259275(-) A-I      3'UTR
chr3:156259286(-) A-I      3'UTR
chr3:156259300(-) A-I      3'UTR
chr3:156259318(-) A-I      3'UTR
chr3:156259417(-) A-I      3'UTR
chr3:156259450(-) A-I      3'UTR
chr3:156259292(-) A-I      3'UTR
chr3:156258150(-) A-I      3'UTR
chr3:156259314(-) A-I      3'UTR
chr3:156258236(-) A-I      3'UTR
chr3:156259381(-) A-I      3'UTR
chr3:156259398(-) A-I      3'UTR
chr3:156259385(-) A-I      3'UTR
chr3:156258213(-) A-I      3'UTR
chr3:156258152(-) A-I      3'UTR
chr3:156259378(-) A-I      3'UTR
chr3:156259380(-) A-I      3'UTR
chr3:156259379(-) A-I      3'UTR
chr3:156259373(-) A-I      3'UTR
chr3:156259372(-) A-I      3'UTR
chr3:156259356(-) A-I      3'UTR
chr3:156259335(-) A-I      3'UTR
chr3:156259311(-) A-I      3'UTR
chr3:156259309(-) A-I      3'UTR
chr3:156259308(-) A-I      3'UTR
chr3:156258151(-) A-I      3'UTR
chr3:156258391(-) A-I      3'UTR
chr3:156258348(-) A-I      3'UTR
chr3:156258332(-) A-I      3'UTR
chr3:156258286(-) A-I      3'UTR
chr3:156258246(-) A-I      3'UTR
chr3:156258276(-) A-I      3'UTR
chr3:156258271(-) A-I      3'UTR
chr3:156258257(-) A-I      3'UTR
chr3:156258255(-) A-I      3'UTR
chr3:156258247(-) A-I      3'UTR
chr3:156259367(-) A-I      3'UTR
chr3:156258319(-) A-I      3'UTR
chr3:156258227(-) A-I      3'UTR
chr3:156258308(-) A-I      3'UTR
chr3:156259370(-) A-I      3'UTR
chr3:156259317(-) A-I      3'UTR
chr3:156259397(-) A-I      3'UTR
chr3:156259406(-) A-I      3'UTR
chr3:156259295(-) A-I      3'UTR
chr3:156259324(-) A-I      3'UTR
chr3:156258393(-) A-I      3'UTR
chr3:156259299(-) A-I      3'UTR
chr3:156258283(-) A-I      3'UTR
chr3:156259229(-) A-I      3'UTR
chr3:156258389(-) A-I      3'UTR
chr3:156259288(-) A-I      3'UTR
chr3:156259363(-) A-I      3'UTR
chr3:156259341(-) A-I      3'UTR
chr3:156259340(-) A-I      3'UTR
chr3:156259396(-) A-I      3'UTR
chr3:156258230(-) A-I      3'UTR
chr3:156259331(-) A-I      3'UTR
chr3:156258205(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SSR3
chr3:156259229(-) A-I exon 3'UTR    21960545   //22327324
chr3:156258319(-) A-I exon 3'UTR    22327324
chr3:156258389(-) A-I exon 3'UTR    22327324
chr3:156259406(-) A-I exon 3'UTR    21960545
chr3:156259407(-) A-I exon 3'UTR    21960545
chr3:156259295(-) A-I exon 3'UTR    21960545
chr3:156259340(-) A-I exon 3'UTR    21960545
chr3:156259341(-) A-I exon 3'UTR    21960545
chr3:156259363(-) A-I exon 3'UTR    21960545
chr3:156259367(-) A-I exon 3'UTR    21960545
chr3:156258205(-) A-G exon 3'UTR    22484847
chr3:156258273(-) A-G exon 3'UTR    22484847
chr3:156258283(-) A-G exon 3'UTR    22484847
chr3:156258295(-) A-G exon 3'UTR    22484847
chr3:156258308(-) A-G exon 3'UTR    22484847
chr3:156258319(-) A-G exon 3'UTR    22484847
chr3:156258338(-) A-G exon 3'UTR    22484847
chr3:156258393(-) A-T exon 3'UTR    22484847
chr3:156258394(-) G-T exon 3'UTR    22484847
chr3:156259223(-) A-G exon 3'UTR    22484847
chr3:156259229(-) A-G exon 3'UTR    22484847
chr3:156259288(-) A-G exon 3'UTR    22484847
chr3:156259295(-) A-G exon 3'UTR    22484847
chr3:156259299(-) A-G exon 3'UTR    22484847
chr3:156259317(-) A-G exon 3'UTR    22484847
chr3:156259324(-) A-G exon 3'UTR    22484847
chr3:156259340(-) A-G exon 3'UTR    22484847
chr3:156259341(-) A-G exon 3'UTR    22484847
chr3:156259363(-) A-G exon 3'UTR    22484847
chr3:156259367(-) A-G exon 3'UTR    22484847
chr3:156259376(-) A-G exon 3'UTR    22484847
chr3:156259391(-) G-A exon 3'UTR    22484847
chr3:156259396(-) A-G exon 3'UTR    22484847
chr3:156259406(-) A-G exon 3'UTR    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SSR3
chr3:156257947-156257948(-) m6A 3'UTR       27773535
chr3:156258030-156258031(-) m6A 3'UTR       27773535
chr3:156258051-156258052(-) m6A 3'UTR       27773535
chr3:156258275-156258276(-) m6A 3'UTR       27773535
chr3:156258390-156258391(-) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BHRF1-2-5p
Exosome B cell line (Raji)     21505438
SSR3
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: SSR3

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

Starting a new search, please wait ...