Basic Information:

  VIRBase ID:  

VHID00279535

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:  MIMAT0000996          ADARB1:  NR_027672     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-5p	ADARB1
miRBase Accession/Entrez ID	MIMAT0000996	104
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ADAR2//DRABA2//DRADA2//NEDHYMS//RED1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ADARB1	chr21:46613344(+) A-I      intronic chr21:46613308(+) A-I      intronic chr21:46613294(+) A-I      intronic chr21:46634852(+) A-I      intronic chr21:46519436(+) A-I      intronic chr21:46503658(+) A-I      intronic chr21:46560992(+) A-I      intronic chr21:46624998(+) A-I      intronic chr21:46613317(+) A-I      intronic chr21:46613316(+) A-I      intronic chr21:46613315(+) A-I      intronic chr21:46639192(+) A-I      intronic chr21:46639191(+) A-I      intronic chr21:46635451(+) A-I      intronic chr21:46635422(+) A-I      intronic chr21:46635215(+) A-I      intronic chr21:46635201(+) A-I      intronic chr21:46503696(+) A-I      intronic chr21:46503763(+) A-I      intronic chr21:46558970(+) A-I      intronic chr21:46544391(+) A-I      intronic chr21:46635443(+) A-I      intronic chr21:46626589(+) A-I      intronic chr21:46639185(+) A-I      intronic chr21:46635444(+) A-I      intronic chr21:46624924(+) A-I      intronic chr21:46544312(+) A-I      intronic chr21:46558975(+) A-I      intronic chr21:46527909(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ADARB1	chr21:46494647-46494648(+) m6A 5'UTR//exon//intron       22575960 chr21:46494681-46494682(+) m6A 5'UTR//exon//intron       22575960 chr21:46499902-46499903(+) Am intron       - chr21:46565441-46565442(+) m6A exon//intron       24209618 chr21:46565557-46565558(+) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr21:46565601-46565602(+) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr21:46565641-46565642(+) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr21:46565728-46565729(+) m6A exon//intron       24284625//24209618//24981863 chr21:46565803-46565804(+) m6A exon//intron       24209618//24981863//22608085 chr21:46565889-46565890(+) m6A exon//intron       24284625//24981863 chr21:46565961-46565962(+) m6A exon//intron       24284625//24981863//22575960 chr21:46566040-46566041(+) m6A exon//intron       24284625 chr21:46582691-46582692(+) Am intron       - chr21:46595671-46595672(+) m6A CDS//exon       24284625 chr21:46595683-46595684(+) m6A CDS//exon       24284625 chr21:46595832-46595833(+) m6A CDS//exon       24284625//22575960//22608085 chr21:46595916-46595917(+) m6A CDS//exon       24284625//24981863//22575960//22608085 chr21:46596008-46596009(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596087-46596088(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596106-46596107(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596159-46596160(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596229-46596230(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596341-46596342(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596353-46596354(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr21:46596454-46596455(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr21:46604501-46604502(+) m6A CDS//intron       - chr21:46624564-46624565(+) m6A CDS//exon       24284625 chr21:46624609-46624610(+) m6A CDS//exon       24284625 chr21:46642089-46642090(+) m6A CDS//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642121-46642122(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642171-46642172(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642184-46642185(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642223-46642224(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642232-46642233(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:46642273-46642274(+) m6A 3'UTR//exon//intron       24284625//25456834//22575960//22608085 chr21:46642369-46642370(+) m6A 3'UTR//exon//intron       24284625 chr21:46643169-46643170(+) m6A 3'UTR//exon//intron       24284625//22608085 chr21:46643212-46643213(+) m6A 3'UTR//exon//intron       24284625//24981863 chr21:46643242-46643243(+) m6A 3'UTR//exon//intron       24284625//24981863 chr21:46643362-46643363(+) m6A 3'UTR//exon//intron       24284625//22575960 chr21:46643529-46643530(+) m6A 3'UTR//intron       24284625//22575960 chr21:46643606-46643607(+) m6A 3'UTR//intron       24284625//22575960 chr21:46643659-46643660(+) m6A 3'UTR//intron       24284625//22575960 chr21:46643667-46643668(+) m6A 3'UTR//intron       24284625//25456834//22575960 chr21:46643673-46643674(+) m6A 3'UTR//intron       24284625//25456834//22575960 chr21:46643792-46643793(+) m6A 3'UTR//intron       24284625//25456834//22575960 chr21:46643816-46643817(+) m6A 3'UTR//intron       24284625//25456834//22575960 chr21:46644472-46644473(+) m6A 3'UTR//intron       24284625 chr21:46644569-46644570(+) m6A 3'UTR//intron       24284625//25456834 chr21:46644619-46644620(+) m6A 3'UTR//intron       24284625//25456834 chr21:46644677-46644678(+) m6A 3'UTR//intron       24284625 chr21:46644703-46644704(+) m6A 3'UTR//intron       24284625 chr21:46644733-46644734(+) m6A 3'UTR//intron       24284625 chr21:46645535-46645536(+) m6A 3'UTR//exon       24284625 chr21:46645548-46645549(+) m6A 3'UTR//exon       24284625 chr21:46645566-46645567(+) m6A 3'UTR//exon       24284625 chr21:46645602-46645603(+) m6A 3'UTR//exon       24284625 chr21:46645692-46645693(+) m6A 3'UTR//exon       24284625 chr21:46645915-46645916(+) m6A 3'UTR//exon       24284625 chr21:46645939-46645940(+) m6A 3'UTR//exon       24284625 chr21:46646094-46646095(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr21:46646136-46646137(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr21:46646152-46646153(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr21:46646158-46646159(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr21:46646268-46646269(+) m6A 3'UTR//exon       24284625//22575960//22608085 chr21:46646299-46646300(+) m6A 3'UTR//exon       24284625//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-5p	Exosome B cell line (Raji)     21505438
	ADARB1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: ADARB1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg