Basic Information:

  VIRBase ID:  

VHID00279530

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-2-5p:  MIMAT0000996          ACTL6A:  NM_178042     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-2-5p	ACTL6A
miRBase Accession/Entrez ID	MIMAT0000996	86
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ACTL6//Arp4//ARPN-BETA//BAF53A//INO80K

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ACTL6A	chr3:179284989(+) A-I      intronic chr3:179284497(+) A-I      intronic chr3:179284536(+) A-I      intronic chr3:179282735(+) A-I      intronic chr3:179284547(+) A-I      intronic chr3:179296654(+) A-I      intronic chr3:179296671(+) A-I      intronic chr3:179297465(+) A-I      intronic chr3:179283060(+) A-I      intronic chr3:179306167(+) A-I      3'UTR chr3:179306115(+) A-I      3'UTR chr3:179305987(+) A-I      3'UTR chr3:179306122(+) A-I      3'UTR chr3:179306127(+) A-I      3'UTR chr3:179306128(+) A-I      3'UTR chr3:179305925(+) A-I      3'UTR chr3:179305934(+) A-I      3'UTR chr3:179306148(+) A-I      3'UTR chr3:179306153(+) A-I      3'UTR chr3:179306164(+) A-I      3'UTR chr3:179305936(+) A-I      3'UTR chr3:179306169(+) A-I      3'UTR chr3:179306171(+) A-I      3'UTR chr3:179305952(+) A-I      3'UTR chr3:179305954(+) A-I      3'UTR chr3:179305977(+) A-I      3'UTR chr3:179284499(+) A-I      intronic chr3:179297526(+) A-I      intronic chr3:179297424(+) A-I      intronic chr3:179297455(+) A-I      intronic chr3:179297750(+) A-I      intronic chr3:179296122(+) A-I      intronic chr3:179297356(+) A-I      intronic chr3:179302243(+) A-I      intronic chr3:179297823(+) A-I      intronic chr3:179303070(+) A-I      intronic chr3:179296264(+) A-I      intronic chr3:179296695(+) A-I      intronic chr3:179302355(+) A-I      intronic chr3:179285034(+) A-I      intronic chr3:179297425(+) A-I      intronic chr3:179296321(+) A-I      intronic chr3:179303073(+) A-I      intronic chr3:179303152(+) A-I      intronic chr3:179284611(+) A-I      intronic chr3:179302426(+) A-I      intronic chr3:179296148(+) A-I      intronic chr3:179296693(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ACTL6A	chr3:179284499(+) A-G intron -    22484847 chr3:179284662(+) A-G intron -    22484847 chr3:179284885(+) A-G intron -    22484847 chr3:179297425(+) A-G intron -    22484847 chr3:179297455(+) A-G intron -    22484847 chr3:179297456(+) A-G intron -    22484847 chr3:179302243(+) A-G intron -    22484847 chr3:179302451(+) T-C intron -    22484847 chr3:179303003(+) A-G intron -    22484847 chr3:179303008(+) A-G intron -    22484847 chr3:179303073(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ACTL6A	chr3:179287677-179287678(+) m6A 5'UTR//CDS//exon       27773535 chr3:179287937-179287938(+) m6A CDS//exon       27773535 chr3:179291162-179291163(+) m6A CDS//exon       - chr3:179293008-179293009(+) m6A exon//intron       27773535 chr3:179293165-179293166(+) m6A exon//intron       27773535 chr3:179294434-179294435(+) m6A 3'UTR//CDS//exon       27773535 chr3:179294459-179294460(+) m6A 3'UTR//CDS//exon       27773535 chr3:179294639-179294640(+) m6A 3'UTR//CDS//exon       27773535 chr3:179298940-179298941(+) m6A CDS       27773535 chr3:179306104-179306105(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-2-5p	Exosome B cell line (Raji)     21505438
	ACTL6A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-2-5p
Interactor2: ACTL6A

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg