Detail Information

Basic Information:


  VIRBase ID:  

VHID00279136

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-1:           SPTY2D1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BHRF1-1 SPTY2D1
miRBase
Accession/Entrez ID		 MIMAT0000995 144108
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - Spt2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SPTY2D1
chr11:18634479(-) A-I      intronic
chr11:18652579(-) A-I      intronic
chr11:18652602(-) A-I      intronic
chr11:18652623(-) A-I      intronic
chr11:18652636(-) A-I      intronic
chr11:18652992(-) A-I      intronic
chr11:18653021(-) A-I      intronic
chr11:18647175(-) A-I      intronic
chr11:18654163(-) A-I      intronic
chr11:18634449(-) A-I      intronic
chr11:18653022(-) A-I      intronic
chr11:18634354(-) A-I      intronic
chr11:18634450(-) A-I      intronic
chr11:18635845(-) A-I      intronic
chr11:18653501(-) A-I      intronic
chr11:18653593(-) A-I      intronic
chr11:18654114(-) A-I      intronic
chr11:18635874(-) A-I      intronic
chr11:18654089(-) A-I      intronic
chr11:18654072(-) A-I      intronic
chr11:18653611(-) A-I      intronic
chr11:18652494(-) A-I      intronic
chr11:18648715(-) A-I      intronic
chr11:18654084(-) A-I      intronic
chr11:18653624(-) A-I      intronic
chr11:18648748(-) A-I      intronic
chr11:18654065(-) A-I      intronic
chr11:18648768(-) A-I      intronic
chr11:18653698(-) A-I      intronic
chr11:18643389(-) A-I      intronic
chr11:18648777(-) A-I      intronic
chr11:18648797(-) A-I      intronic
chr11:18654074(-) A-I      intronic
chr11:18653606(-) A-I      intronic
chr11:18653699(-) A-I      intronic
chr11:18644335(-) A-I      intronic
chr11:18653928(-) A-I      intronic
chr11:18654034(-) A-I      intronic
chr11:18654073(-) A-I      intronic
chr11:18654060(-) A-I      intronic
chr11:18652523(-) A-I      intronic
chr11:18652546(-) A-I      intronic
chr11:18652550(-) A-I      intronic
chr11:18649236(-) A-I      intronic
chr11:18653631(-) A-I      intronic
chr11:18647638(-) A-I      intronic
chr11:18647224(-) A-I      intronic
chr11:18647560(-) A-I      intronic
chr11:18654169(-) A-I      intronic
chr11:18635861(-) A-I      intronic
chr11:18634553(-) A-I      intronic
chr11:18647594(-) A-I      intronic
chr11:18644332(-) A-I      intronic
chr11:18653521(-) A-I      intronic
chr11:18653580(-) A-I      intronic
chr11:18653527(-) A-I      intronic
chr11:18654024(-) A-I      intronic
chr11:18634310(-) A-I      intronic
chr11:18650939(-) A-I      intronic
chr11:18653536(-) A-I      intronic
chr11:18653610(-) A-I      intronic
chr11:18652903(-) A-I      intronic
chr11:18654127(-) A-I      intronic
chr11:18650964(-) A-I      intronic
chr11:18652665(-) A-I      intronic
chr11:18654090(-) A-I      intronic
chr11:18653513(-) A-I      intronic
chr11:18653477(-) A-I      intronic
chr11:18654112(-) A-I      intronic
chr11:18652454(-) A-I      intronic
chr11:18653476(-) A-I      intronic
chr11:18653581(-) A-I      intronic
chr11:18652510(-) A-I      intronic
chr11:18654033(-) A-I      intronic
chr11:18654063(-) A-I      intronic
chr11:18652554(-) A-I      intronic
chr11:18644350(-) A-I      intronic
chr11:18634476(-) A-I      intronic
chr11:18653991(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SPTY2D1
chr11:18628625-18628626(-) m6A 3'UTR       24209618
chr11:18628639-18628640(-) m6A 3'UTR       24209618
chr11:18630912-18630913(-) m6A 3'UTR       22608085
chr11:18630968-18630969(-) m6A 3'UTR       22608085
chr11:18630974-18630975(-) m6A 3'UTR       22608085
chr11:18631344-18631345(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr11:18631477-18631478(-) m6A CDS       24981863//27773535//27371828//22608085
chr11:18631494-18631495(-) m6A CDS       24981863//27773535//27371828//22608085
chr11:18633746-18633747(-) m6A exon//intron       24981863//27773535//22608085
chr11:18633785-18633786(-) m6A exon//intron       27773535
chr11:18633854-18633855(-) m6A exon//intron       27773535
chr11:18636253-18636254(-) m6A CDS//exon       24981863//26404942
chr11:18636263-18636264(-) m6A CDS//exon       24981863//26404942
chr11:18636281-18636282(-) m6A CDS//exon       24284625//24981863//26404942//22608085
chr11:18636307-18636308(-) m6A CDS//exon       24284625//24981863//26404942//22608085
chr11:18636398-18636399(-) m6A CDS//exon       24284625//25456834//24981863//22608085
chr11:18636449-18636450(-) m6A CDS//exon       24284625//25456834//24981863//22608085
chr11:18636512-18636513(-) m6A CDS//exon       24284625//24981863//22608085
chr11:18636538-18636539(-) m6A CDS//exon       24284625//24981863//27371828//22608085
chr11:18636599-18636600(-) m6A CDS//exon       24284625//24981863//27371828//22608085
chr11:18636826-18636827(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr11:18636841-18636842(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr11:18636902-18636903(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr11:18637001-18637002(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr11:18637022-18637023(-) m6A CDS//exon       24284625//27773535//22608085
chr11:18637077-18637078(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637097-18637098(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637154-18637155(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637165-18637166(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637172-18637173(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637217-18637218(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637274-18637275(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr11:18637317-18637318(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22608085
chr11:18637355-18637356(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22608085
chr11:18637376-18637377(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22608085
chr11:18637465-18637466(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//27371828//27773536//22608085
chr11:18637555-18637556(-) m6A CDS//exon       24209618//24981863//28052920//27773535//27371828//22608085
chr11:18637589-18637590(-) m6A CDS//exon       24209618//24981863//27773535//27371828//22608085
chr11:18637616-18637617(-) m6A CDS//exon       24209618//24981863//27773535//27371828//22608085
chr11:18638498-18638499(-) m6A CDS//exon       24981863//27773535//27371828
chr11:18655765-18655766(-) m6A CDS//exon//intron       24981863//27371828
chr11:18655799-18655800(-) m6A CDS//exon//intron       24981863//27371828
chr11:18656017-18656018(-) m6A 5'UTR//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BHRF1-1
Exosome Jurkat-derived T cell line (J77cl20)     21505438
SPTY2D1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BHRF1-1
Interactor2: SPTY2D1

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression Downregulation
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

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