Basic Information:

  VIRBase ID:  

VHID00278176

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-1:  MIMAT0000995          PTPN23:  NM_001304482     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-1	PTPN23
miRBase Accession/Entrez ID	MIMAT0000995	25930
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HD-PTP//HDPTP//NEDBASS//PTP-TD14

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PTPN23	chr3:47442094(+) A-I      intronic chr3:47442082(+) A-I      intronic chr3:47441552(+) A-I      intronic chr3:47441340(+) A-I      intronic chr3:47441327(+) A-I      intronic chr3:47439714(+) A-I      intronic chr3:47439695(+) A-I      intronic chr3:47427020(+) A-I      intronic chr3:47439633(+) A-I      intronic chr3:47439625(+) A-I      intronic chr3:47439547(+) A-I      intronic chr3:47439422(+) A-I      intronic chr3:47439229(+) A-I      intronic chr3:47438259(+) A-I      intronic chr3:47438155(+) A-I      intronic chr3:47437990(+) A-I      intronic chr3:47437968(+) A-I      intronic chr3:47437914(+) A-I      intronic chr3:47437912(+) A-I      intronic chr3:47427930(+) A-I      intronic chr3:47427903(+) A-I      intronic chr3:47442842(+) A-I      intronic chr3:47437889(+) A-I      intronic chr3:47437887(+) A-I      intronic chr3:47434535(+) A-I      intronic chr3:47433745(+) A-I      intronic chr3:47433707(+) A-I      intronic chr3:47427017(+) A-I      intronic chr3:47427755(+) A-I      intronic chr3:47427756(+) A-I      intronic chr3:47427797(+) A-I      intronic chr3:47438336(+) A-I      intronic chr3:47438341(+) A-I      intronic chr3:47426986(+) A-I      intronic chr3:47427008(+) A-I      intronic chr3:47427016(+) A-I      intronic chr3:47427061(+) A-I      intronic chr3:47427083(+) A-I      intronic chr3:47433699(+) A-I      intronic chr3:47433440(+) A-I      intronic chr3:47430178(+) A-I      intronic chr3:47427053(+) A-I      intronic chr3:47432553(+) A-I      intronic chr3:47431507(+) A-I      intronic chr3:47431392(+) A-I      intronic chr3:47439639(+) A-I      intronic chr3:47431223(+) A-I      intronic chr3:47431209(+) A-I      intronic chr3:47426957(+) A-I      intronic chr3:47426457(+) A-I      intronic chr3:47426386(+) A-I      intronic chr3:47442871(+) A-I      intronic chr3:47431143(+) A-I      intronic chr3:47442712(+) A-I      intronic chr3:47442598(+) A-I      intronic chr3:47442582(+) A-I      intronic chr3:47442518(+) A-I      intronic chr3:47442120(+) A-I      intronic chr3:47438305(+) A-I      intronic chr3:47444325(+) A-I      intronic chr3:47445236(+) A-I      intronic chr3:47433691(+) A-I      intronic chr3:47430976(+) A-I      intronic chr3:47445651(+) A-I      intronic chr3:47441328(+) A-I      intronic chr3:47439690(+) A-I      intronic chr3:47441417(+) A-I      intronic chr3:47439746(+) A-I      intronic chr3:47439179(+) A-I      intronic chr3:47433693(+) A-I      intronic chr3:47445828(+) A-I      intronic chr3:47428909(+) A-I      intronic chr3:47433879(+) A-I      intronic chr3:47445811(+) A-I      intronic chr3:47437810(+) A-I      intronic chr3:47438233(+) A-I      intronic chr3:47440227(+) A-I      intronic chr3:47442836(+) A-I      intronic chr3:47441468(+) A-I      intronic chr3:47442862(+) A-I      intronic chr3:47437807(+) A-I      intronic chr3:47432713(+) A-I      intronic chr3:47432525(+) A-I      intronic chr3:47438326(+) A-I      intronic chr3:47443870(+) A-I      intronic chr3:47441503(+) A-I      intronic chr3:47424385(+) A-I      intronic chr3:47438260(+) A-I      intronic chr3:47441334(+) A-I      intronic chr3:47433939(+) A-I      intronic chr3:47429716(+) A-I      intronic chr3:47445241(+) A-I      intronic chr3:47438264(+) A-I      intronic chr3:47441574(+) A-I      intronic chr3:47426353(+) A-I      intronic chr3:47442888(+) A-I      intronic chr3:47430355(+) A-I      intronic chr3:47439395(+) A-I      intronic chr3:47430957(+) A-I      intronic chr3:47445495(+) A-I      intronic chr3:47445705(+) A-I      intronic chr3:47445465(+) A-I      intronic chr3:47445537(+) A-I      intronic chr3:47424416(+) A-I      intronic chr3:47427795(+) A-I      intronic chr3:47441447(+) A-I      intronic chr3:47439791(+) A-I      intronic chr3:47445221(+) A-I      intronic chr3:47427047(+) A-I      intronic chr3:47439652(+) A-I      intronic chr3:47441563(+) A-I      intronic chr3:47428862(+) A-I      intronic chr3:47443950(+) A-I      intronic chr3:47432596(+) A-I      intronic chr3:47445459(+) A-I      intronic chr3:47442100(+) A-I      intronic chr3:47443909(+) A-I      intronic chr3:47445675(+) A-I      intronic chr3:47441409(+) A-I      intronic chr3:47439699(+) A-I      intronic chr3:47428948(+) A-I      intronic chr3:47425893(+) A-I      intronic chr3:47440307(+) A-I      intronic chr3:47444032(+) A-I      intronic chr3:47439621(+) A-I      intronic chr3:47438331(+) A-I      intronic chr3:47437809(+) A-I      intronic chr3:47439576(+) A-I      intronic chr3:47445452(+) A-I      intronic chr3:47431075(+) A-I      intronic chr3:47438147(+) A-I      intronic chr3:47438250(+) A-I      intronic chr3:47441467(+) A-I      intronic chr3:47437801(+) A-I      intronic chr3:47445670(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PTPN23	chr3:47426353(+) A-G intron -    22484847 chr3:47427047(+) A-G intron -    22484847 chr3:47429716(+) A-G intron -    22484847 chr3:47430355(+) A-G intron -    22484847 chr3:47430976(+) A-G intron -    22484847 chr3:47432606(+) A-G intron -    22484847 chr3:47438147(+) A-G intron -    22484847 chr3:47438233(+) A-G intron -    22484847 chr3:47438260(+) A-G intron -    22484847 chr3:47438264(+) A-G intron -    22484847 chr3:47438331(+) A-G intron -    22484847 chr3:47439179(+) A-G intron -    22484847 chr3:47439253(+) A-G intron -    22484847 chr3:47439277(+) A-G intron -    22484847 chr3:47439621(+) A-G intron -    22484847 chr3:47439624(+) A-G intron -    22484847 chr3:47439652(+) A-G intron -    22484847 chr3:47439690(+) A-G intron -    22484847 chr3:47439691(+) A-G intron -    22484847 chr3:47439699(+) A-G intron -    22484847 chr3:47441417(+) A-G intron -    22484847 chr3:47441447(+) A-G intron -    22484847 chr3:47443870(+) A-G intron -    22484847 chr3:47444032(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PTPN23	chr3:47422623-47422624(+) m6A CDS//exon       24284625//24981863 chr3:47422667-47422668(+) m1A CDS//exon       26863410//26863196 chr3:47437657-47437658(+) m6A CDS//exon//intron       24284625 chr3:47437679-47437680(+) m6A CDS//exon//intron       - chr3:47449053-47449054(+) m6A 3'UTR//CDS       - chr3:47449216-47449217(+) m6A 3'UTR//CDS       - chr3:47449225-47449226(+) m6A 3'UTR//CDS       - chr3:47449259-47449260(+) m6A 3'UTR//CDS       - chr3:47449875-47449876(+) m6A 3'UTR//CDS       22575960 chr3:47449959-47449960(+) m6A 3'UTR//CDS       22575960 chr3:47450307-47450308(+) m6A 3'UTR//CDS       22575960 chr3:47451149-47451150(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451163-47451164(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451194-47451195(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451224-47451225(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451233-47451234(+) Cm 3'UTR//CDS//exon       - chr3:47451320-47451321(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451427-47451428(+) m1A 3'UTR//CDS//exon       26863196 chr3:47451506-47451507(+) m6A 3'UTR//CDS//exon       24284625 chr3:47451636-47451637(+) m6A 3'UTR//CDS       24284625 chr3:47451986-47451987(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr3:47452257-47452258(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863 chr3:47452361-47452362(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863 chr3:47452461-47452462(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr3:47452602-47452603(+) m6A 3'UTR//CDS       24981863 chr3:47452640-47452641(+) m6A 3'UTR//CDS       24981863 chr3:47452775-47452776(+) m6A 3'UTR//CDS       25456834//24981863 chr3:47452862-47452863(+) m6A 3'UTR//CDS       24284625//25456834//24981863//22608085 chr3:47452896-47452897(+) m6A 3'UTR//CDS       24284625//25456834//24981863//22608085 chr3:47452949-47452950(+) m6A 3'UTR//CDS       - chr3:47454211-47454212(+) m6A 3'UTR//CDS       24284625 chr3:47454220-47454221(+) m6A 3'UTR//CDS       24284625//24981863 chr3:47454535-47454536(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr3:47454554-47454555(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960 chr3:47454657-47454658(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr3:47454669-47454670(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr3:47454675-47454676(+) m6A 3'UTR       24284625//24209618//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	PTPN23	Chromatin K562 cells     - Cytosol HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-1
Interactor2: PTPN23

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg