Basic Information:

  VIRBase ID:  

VHID00278145

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BHRF1-1:  MIMAT0000995          ZKSCAN5:  NM_014569     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BHRF1-1	ZKSCAN5
miRBase Accession/Entrez ID	MIMAT0000995	23660
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ZFP-95//ZFP95//ZNF914//ZSCAN37

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZKSCAN5	chr7:99126312(+) A-I      intronic chr7:99128559(+) A-I      intronic chr7:99128509(+) A-I      intronic chr7:99115929(+) A-I      intronic chr7:99128430(+) A-I      intronic chr7:99127542(+) A-I      intronic chr7:99107242(+) A-I      intronic chr7:99127439(+) A-I      intronic chr7:99106225(+) A-I      intronic chr7:99107274(+) A-I      intronic chr7:99120330(+) A-I      intronic chr7:99120332(+) A-I      intronic chr7:99120344(+) A-I      intronic chr7:99126238(+) A-I      intronic chr7:99105423(+) A-I      intronic chr7:99105345(+) A-I      intronic chr7:99128574(+) A-I      intronic chr7:99105649(+) A-I      intronic chr7:99121163(+) A-I      intronic chr7:99121763(+) A-I      intronic chr7:99122537(+) A-I      intronic chr7:99122567(+) A-I      intronic chr7:99122704(+) A-I      intronic chr7:99122721(+) A-I      intronic chr7:99122914(+) A-I      intronic chr7:99106912(+) A-I      intronic chr7:99105759(+) A-I      intronic chr7:99105769(+) A-I      intronic chr7:99105771(+) A-I      intronic chr7:99105775(+) A-I      intronic chr7:99105802(+) A-I      intronic chr7:99105863(+) A-I      intronic chr7:99106113(+) A-I      intronic chr7:99106245(+) A-I      intronic chr7:99106261(+) A-I      intronic chr7:99106643(+) A-I      intronic chr7:99106651(+) A-I      intronic chr7:99106729(+) A-I      intronic chr7:99106801(+) A-I      intronic chr7:99106930(+) A-I      intronic chr7:99107170(+) A-I      intronic chr7:99107176(+) A-I      intronic chr7:99107189(+) A-I      intronic chr7:99107231(+) A-I      intronic chr7:99107235(+) A-I      intronic chr7:99107350(+) A-I      intronic chr7:99107684(+) A-I      intronic chr7:99126220(+) A-I      intronic chr7:99120573(+) A-I      intronic chr7:99124823(+) A-I      intronic chr7:99124815(+) A-I      intronic chr7:99124803(+) A-I      intronic chr7:99124751(+) A-I      intronic chr7:99124295(+) A-I      intronic chr7:99124247(+) A-I      intronic chr7:99123036(+) A-I      intronic chr7:99122917(+) A-I      intronic chr7:99107747(+) A-I      intronic chr7:99108059(+) A-I      intronic chr7:99108118(+) A-I      intronic chr7:99108539(+) A-I      intronic chr7:99111110(+) A-I      intronic chr7:99111227(+) A-I      intronic chr7:99111396(+) A-I      intronic chr7:99111441(+) A-I      intronic chr7:99111502(+) A-I      intronic chr7:99111508(+) A-I      intronic chr7:99113634(+) A-I      intronic chr7:99113701(+) A-I      intronic chr7:99114814(+) A-I      intronic chr7:99115049(+) A-I      intronic chr7:99115108(+) A-I      intronic chr7:99115193(+) A-I      intronic chr7:99116660(+) A-I      intronic chr7:99116685(+) A-I      intronic chr7:99116779(+) A-I      intronic chr7:99116782(+) A-I      intronic chr7:99116964(+) A-I      intronic chr7:99118384(+) A-I      intronic chr7:99118465(+) A-I      intronic chr7:99118467(+) A-I      intronic chr7:99118966(+) A-I      intronic chr7:99118973(+) A-I      intronic chr7:99105673(+) A-I      intronic chr7:99120152(+) A-I      intronic chr7:99120196(+) A-I      intronic chr7:99120319(+) A-I      intronic chr7:99120770(+) A-I      intronic chr7:99120739(+) A-I      intronic chr7:99120637(+) A-I      intronic chr7:99126136(+) A-I      intronic chr7:99101735(+) A-I      5'UTR chr7:99111231(+) A-I      intronic chr7:99107585(+) A-I      intronic chr7:99124881(+) A-I      intronic chr7:99112427(+) A-I      intronic chr7:99116565(+) A-I      intronic chr7:99116965(+) A-I      intronic chr7:99118422(+) A-I      intronic chr7:99111452(+) A-I      intronic chr7:99124319(+) A-I      intronic chr7:99112445(+) A-I      intronic chr7:99124688(+) A-I      intronic chr7:99122857(+) A-I      intronic chr7:99116994(+) A-I      intronic chr7:99117135(+) A-I      intronic chr7:99115802(+) A-I      intronic chr7:99106171(+) A-I      intronic chr7:99111222(+) A-I      intronic chr7:99105268(+) A-I      intronic chr7:99115924(+) A-I      intronic chr7:99124873(+) A-I      intronic chr7:99111449(+) A-I      intronic chr7:99106170(+) A-I      intronic chr7:99126119(+) A-I      intronic chr7:99105668(+) A-I      intronic chr7:99111252(+) A-I      intronic chr7:99120578(+) A-I      intronic chr7:99121173(+) A-I      intronic chr7:99108341(+) A-I      intronic chr7:99105398(+) A-I      intronic chr7:99124833(+) A-I      intronic chr7:99105382(+) A-I      intronic chr7:99122057(+) A-I      intronic chr7:99125514(+) A-I      intronic chr7:99126192(+) A-I      intronic chr7:99106274(+) A-I      intronic chr7:99124771(+) A-I      intronic chr7:99106251(+) A-I      intronic chr7:99104435(+) A-I      intronic chr7:99112627(+) A-I      intronic chr7:99106711(+) A-I      intronic chr7:99121097(+) A-I      intronic chr7:99121168(+) A-I      intronic chr7:99120290(+) A-I      intronic chr7:99108332(+) A-I      intronic chr7:99120762(+) A-I      intronic chr7:99115848(+) A-I      intronic chr7:99121059(+) A-I      intronic chr7:99106304(+) A-I      intronic chr7:99107700(+) A-I      intronic chr7:99115197(+) A-I      intronic chr7:99112772(+) A-I      intronic chr7:99115884(+) A-I      intronic chr7:99120742(+) A-I      intronic chr7:99117027(+) A-I      intronic chr7:99126833(+) A-I      intronic chr7:99115094(+) A-I      intronic chr7:99101696(+) A-I      5'UTR chr7:99101996(+) A-I      5'UTR chr7:99101831(+) A-I      5'UTR chr7:99101652(+) A-I      5'UTR chr7:99101695(+) A-I      5'UTR chr7:99101721(+) A-I      5'UTR chr7:99101730(+) A-I      5'UTR chr7:99101675(+) A-I      5'UTR chr7:99115790(+) A-I      intronic chr7:99111609(+) A-I      intronic chr7:99114815(+) A-I      intronic chr7:99117030(+) A-I      intronic chr7:99105716(+) A-I      intronic chr7:99114939(+) A-I      intronic chr7:99118452(+) A-I      intronic chr7:99105449(+) A-I      intronic chr7:99107591(+) A-I      intronic chr7:99124303(+) A-I      intronic chr7:99123021(+) A-I      intronic chr7:99119023(+) A-I      intronic chr7:99128418(+) A-I      intronic chr7:99113700(+) A-I      intronic chr7:99113694(+) A-I      intronic chr7:99108577(+) A-I      intronic chr7:99107009(+) A-I      intronic chr7:99107599(+) A-I      intronic chr7:99115796(+) A-I      intronic chr7:99112446(+) A-I      intronic chr7:99106186(+) A-I      intronic chr7:99105756(+) A-I      intronic chr7:99111613(+) A-I      intronic chr7:99111507(+) A-I      intronic chr7:99117174(+) A-I      intronic chr7:99115127(+) A-I      intronic chr7:99122794(+) A-I      intronic chr7:99109677(+) A-I      intronic chr7:99124752(+) A-I      intronic chr7:99107229(+) A-I      intronic chr7:99120197(+) A-I      intronic chr7:99120677(+) A-I      intronic chr7:99122700(+) A-I      intronic chr7:99117034(+) A-I      intronic chr7:99106894(+) A-I      intronic chr7:99106122(+) A-I      intronic chr7:99105450(+) A-I      intronic chr7:99124317(+) A-I      intronic chr7:99128417(+) A-I      intronic chr7:99111548(+) A-I      intronic chr7:99106741(+) A-I      intronic chr7:99115323(+) A-I      intronic chr7:99126278(+) A-I      intronic chr7:99111156(+) A-I      intronic chr7:99105422(+) A-I      intronic chr7:99115933(+) A-I      intronic chr7:99111547(+) A-I      intronic chr7:99121835(+) A-I      intronic chr7:99121011(+) A-I      intronic chr7:99114870(+) A-I      intronic chr7:99120209(+) A-I      intronic chr7:99118354(+) A-I      intronic chr7:99111455(+) A-I      intronic chr7:99122111(+) A-I      intronic chr7:99122642(+) A-I      intronic chr7:99124278(+) A-I      intronic chr7:99122840(+) A-I      intronic chr7:99116571(+) A-I      intronic chr7:99105336(+) A-I      intronic chr7:99121164(+) A-I      intronic chr7:99107632(+) A-I      intronic chr7:99118962(+) A-I      intronic chr7:99120320(+) A-I      intronic chr7:99108457(+) A-I      intronic chr7:99105667(+) A-I      intronic chr7:99114728(+) A-I      intronic chr7:99126834(+) A-I      intronic chr7:99120693(+) A-I      intronic chr7:99105307(+) A-I      intronic chr7:99114915(+) A-I      intronic chr7:99115879(+) A-I      intronic chr7:99115103(+) A-I      intronic chr7:99111593(+) A-I      intronic chr7:99122934(+) A-I      intronic chr7:99111182(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZKSCAN5	chr7:99103736(+) A-I exon CDS    15342557 chr7:99123465(+) A-I exon CDS    15342557 chr7:99130514(+) A-I exon 3'UTR    15342557 chr7:99131067(+) A-I exon 3'UTR    15342557 chr7:99104493(+) G-T intron -    22484847 chr7:99105307(+) A-G intron -    22484847 chr7:99105341(+) A-G intron -    22484847 chr7:99105406(+) A-G intron -    22484847 chr7:99105654(+) A-G intron -    22484847 chr7:99105668(+) A-G intron -    22484847 chr7:99105756(+) A-G intron -    22484847 chr7:99106122(+) A-G intron -    22484847 chr7:99106241(+) A-G intron -    22484847 chr7:99106251(+) A-G intron -    22484847 chr7:99106274(+) A-G intron -    22484847 chr7:99106278(+) A-G intron -    22484847 chr7:99106304(+) A-G intron -    22484847 chr7:99106711(+) A-G intron -    22484847 chr7:99106874(+) A-G intron -    22484847 chr7:99107009(+) A-G intron -    22484847 chr7:99107121(+) A-G intron -    22484847 chr7:99107164(+) A-G intron -    22484847 chr7:99107296(+) A-G intron -    22484847 chr7:99107632(+) A-G intron -    22484847 chr7:99107688(+) A-G intron -    22484847 chr7:99107700(+) A-G intron -    22484847 chr7:99108577(+) A-G intron -    22484847 chr7:99111091(+) A-G intron -    22484847 chr7:99111222(+) A-G intron -    22484847 chr7:99111231(+) A-G intron -    22484847 chr7:99111449(+) A-G intron -    22484847 chr7:99111450(+) A-G intron -    22484847 chr7:99111452(+) A-G intron -    22484847 chr7:99111455(+) A-G intron -    22484847 chr7:99111507(+) A-G intron -    22484847 chr7:99111547(+) A-G intron -    22484847 chr7:99111548(+) A-G intron -    22484847 chr7:99111593(+) A-G intron -    22484847 chr7:99112942(+) A-G intron -    22484847 chr7:99113694(+) A-G intron -    22484847 chr7:99113700(+) A-G intron -    22484847 chr7:99115094(+) A-G intron -    22484847 chr7:99115103(+) A-G intron -    22484847 chr7:99115120(+) A-G intron -    22484847 chr7:99115197(+) A-G intron -    22484847 chr7:99115790(+) A-G intron -    22484847 chr7:99115924(+) A-G intron -    22484847 chr7:99116862(+) A-G intron -    22484847 chr7:99116865(+) A-G intron -    22484847 chr7:99116994(+) A-G intron -    22484847 chr7:99117162(+) A-G intron -    22484847 chr7:99117174(+) A-G intron -    22484847 chr7:99118354(+) A-G intron -    22484847 chr7:99118422(+) A-G intron -    22484847 chr7:99118452(+) A-G intron -    22484847 chr7:99118458(+) A-G intron -    22484847 chr7:99118962(+) A-G intron -    22484847 chr7:99119023(+) A-G intron -    22484847 chr7:99120320(+) A-G intron -    22484847 chr7:99120699(+) A-G intron -    22484847 chr7:99121164(+) A-G intron -    22484847 chr7:99124278(+) A-G intron -    22484847 chr7:99124688(+) A-G intron -    22484847 chr7:99124752(+) A-G intron -    22484847 chr7:99124833(+) A-G intron -    22484847 chr7:99125514(+) A-G intron -    22484847 chr7:99126189(+) A-G intron -    22484847 chr7:99126192(+) A-G intron -    22484847 chr7:99126278(+) A-G intron -    22484847 chr7:99126318(+) A-G intron -    22484847 chr7:99126828(+) A-G intron -    22484847 chr7:99126833(+) A-G intron -    22484847 chr7:99126834(+) A-G intron -    22484847 chr7:99128418(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZKSCAN5	chr7:99102942-99102943(+) m6A 5'UTR//intron       24981863 chr7:99103614-99103615(+) m6A 5'UTR//intron       24284625//24209618//24981863//22608085 chr7:99103649-99103650(+) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:99103698-99103699(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99103704-99103705(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99103718-99103719(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99103737-99103738(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99103767-99103768(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99103808-99103809(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99103855-99103856(+) m6A CDS       24284625//24981863//22608085 chr7:99104002-99104003(+) m6A CDS       24284625//24981863 chr7:99104059-99104060(+) m6A CDS       24284625 chr7:99104074-99104075(+) m6A CDS       24284625 chr7:99110163-99110164(+) m6A CDS       24284625 chr7:99123450-99123451(+) m6A CDS       24284625//22608085 chr7:99123514-99123515(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99123546-99123547(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99123660-99123661(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99123741-99123742(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr7:99123778-99123779(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22608085 chr7:99123862-99123863(+) m6A 3'UTR//CDS       24284625//22608085 chr7:99123975-99123976(+) m6A 3'UTR//CDS       22608085 chr7:99124003-99124004(+) m6A 3'UTR//CDS       22608085 chr7:99128751-99128752(+) m6A 3'UTR//CDS       22608085 chr7:99128799-99128800(+) m6A 3'UTR//CDS       24981863//22608085 chr7:99128806-99128807(+) m6A 3'UTR//CDS       24981863//22608085 chr7:99128819-99128820(+) m6A 3'UTR//CDS       24981863//27773535//22608085 chr7:99128920-99128921(+) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085 chr7:99128943-99128944(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99128992-99128993(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129076-99129077(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129244-99129245(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22608085 chr7:99129301-99129302(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22608085 chr7:99129385-99129386(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:99129453-99129454(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:99129471-99129472(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22608085 chr7:99129543-99129544(+) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085 chr7:99129563-99129564(+) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085 chr7:99129634-99129635(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129748-99129749(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129805-99129806(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129827-99129828(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr7:99129894-99129895(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085 chr7:99129910-99129911(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085 chr7:99129970-99129971(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr7:99130017-99130018(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr7:99130027-99130028(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr7:99130104-99130105(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:99130127-99130128(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:99130180-99130181(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99130187-99130188(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99130200-99130201(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:99130331-99130332(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:99130418-99130419(+) m6A 3'UTR       24284625//24981863//22608085 chr7:99130511-99130512(+) m6A 3'UTR       24284625//24981863//22608085 chr7:99130597-99130598(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr7:99130637-99130638(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:99130657-99130658(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:99130673-99130674(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr7:99130715-99130716(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr7:99130733-99130734(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr7:99131344-99131345(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BHRF1-1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ZKSCAN5	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BHRF1-1
Interactor2: ZKSCAN5

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).