Detail Information

Basic Information:


  VIRBase ID:  

VHID00276938

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8589

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol EBER2 HFM1
miRBase
Accession/Entrez ID		 EBER2 164045
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category lncRNA mRNA
Alias - helicase//MER3//POF9//SEC63D1//Si-11//Si-11-6

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HFM1
chr1:91852808(-) A-I      intronic
chr1:91852831(-) A-I      intronic
chr1:91852834(-) A-I      intronic
chr1:91852847(-) A-I      intronic
chr1:91771858(-) A-I      intronic
chr1:91855907(-) A-I      intronic
chr1:91769316(-) A-I      intronic
chr1:91852837(-) A-I      intronic
chr1:91852793(-) A-I      intronic
chr1:91852801(-) A-I      intronic
chr1:91729215(-) A-I      intronic
chr1:91771863(-) A-I      intronic
chr1:91771876(-) A-I      intronic
chr1:91771888(-) A-I      intronic
chr1:91855827(-) A-I      intronic
chr1:91729064(-) A-I      intronic
chr1:91729202(-) A-I      intronic
chr1:91810436(-) A-I      intronic
chr1:91771299(-) A-I      intronic
chr1:91729106(-) A-I      intronic
chr1:91823717(-) A-I      intronic
chr1:91814285(-) A-I      intronic
chr1:91771187(-) A-I      intronic
chr1:91855933(-) A-I      intronic
chr1:91782908(-) A-I      intronic
chr1:91805766(-) A-I      intronic
chr1:91771670(-) A-I      intronic
chr1:91810452(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HFM1
chr1:91852779-91852780(-) Gm intron       -
chr1:91852810-91852811(-) Y intron       16381836//25192136
chr1:91852811-91852812(-) Gm intron       16381836
chr1:91852812-91852813(-) Um intron       16381836
chr1:91852816-91852817(-) Gm intron       16381836
chr1:91852839-91852840(-) Y intron       16381836//25192136
chr1:91852853-91852854(-) Y intron       16381836//25192136
chr1:91852854-91852855(-) Cm intron       16381836
chr1:91852868-91852869(-) Y intron       16381836//25192136
chr1:91852879-91852880(-) Y intron       16381836//25192136
chr1:91852887-91852888(-) Y intron       16381836//25192136
chr1:91852890-91852891(-) Y intron       16381836//25192136
chr1:91852907-91852908(-) Y intron       16381836//25192136
chr1:91852918-91852919(-) Gm intron       16381836
chr1:91852940-91852941(-) Gm intron       16381836
chr1:91852949-91852950(-) Y intron       16381836//25192136
chr1:91852957-91852958(-) Y intron       16381836
chr1:91852998-91852999(-) Y intron       16381836//25192136
chr1:91853004-91853005(-) Um intron       16381836
chr1:91853011-91853012(-) Y intron       16381836//25192136
chr1:91853014-91853015(-) Y intron       16381836//25192136
chr1:91853017-91853018(-) Y intron       16381836//25192136
chr1:91853082-91853083(-) Gm intron       16381836
chr1:91853083-91853084(-) Um intron       16381836
chr1:91853114-91853115(-) Gm intron       16381836
chr1:91870283-91870284(-) m6A 5'UTR//intron       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate EBER2
EBV-postitive Burkitt lymphoma-derived cell line (Raji) Cytoplasm     1332043
EBV-postitive Burkitt lymphoma-derived cell line (Raji) Nucleus     1332043
HFM1
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: EBER2
Interactor2: HFM1

Evidence Support:


Strong-Evidence ChIP
Weak-Evidence RNA-Seq
Support Database ViRBase

References:


PMID 30176159 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line BJAB-B1 lymphoma cells Interactor2 expression None
Description Table 1.EBER2-interacting host RNAs. Gene ID, genome coordinates, and raw read count at maximum peak height are shown.

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