Basic Information:

  VIRBase ID:  

VHID00275427

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL69:  MIMAT0029123          DEPDC1B:  NM_001145208     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL69	DEPDC1B
miRBase Accession/Entrez ID	MIMAT0029123	55789
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BRCC3//XTP1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DEPDC1B	chr5:59945763(-) A-I      intronic chr5:59937316(-) A-I      intronic chr5:59964240(-) A-I      intronic chr5:59977712(-) A-I      intronic chr5:59983387(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DEPDC1B	chr5:59977712(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DEPDC1B	chr5:59893404-59893405(-) m6A 3'UTR       25456834//24981863//27773535//22608085 chr5:59893471-59893472(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr5:59893477-59893478(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr5:59893508-59893509(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr5:59893549-59893550(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr5:59893599-59893600(-) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085 chr5:59893651-59893652(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:59893657-59893658(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:59893663-59893664(-) m6A 3'UTR//CDS       24981863//27773535//22608085 chr5:59982949-59982950(-) Y 3'UTR//CDS       26075521 chr5:59995985-59995986(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DEPDC1B	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL69
Interactor2: DEPDC1B

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg