Basic Information:

  VIRBase ID:  

VHID00273640

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL69:  MIMAT0029123          HMGN2:  NM_005517     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL69	HMGN2
miRBase Accession/Entrez ID	MIMAT0029123	3151
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HMG17

RNA Editing:

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	HMGN2	chr1:26802464(+) T-A intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HMGN2	chr1:26798973-26798974(+) m6A exon       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr1:26798982-26798983(+) m6A exon       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr1:26799009-26799010(+) m1A 5'UTR//exon       26863196//26863410 chr1:26799031-26799032(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828//22575960 chr1:26799931-26799932(+) m6A exon//intron       24209618//24981863//22575960 chr1:26800053-26800054(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800071-26800072(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800139-26800140(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800262-26800263(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800270-26800271(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800280-26800281(+) m6A exon//intron       24209618//24981863//27773535//22575960 chr1:26800345-26800346(+) m6A exon//intron       27773535 chr1:26800459-26800460(+) m6A exon//intron       - chr1:26800479-26800480(+) m6A exon//intron       24981863 chr1:26800577-26800578(+) m6A CDS//exon       24981863//27773535//27371828//22575960 chr1:26801149-26801150(+) m6A CDS//exon       24981863//27773535//27371828//22575960 chr1:26801549-26801550(+) m6A exon//intron       24981863 chr1:26801777-26801778(+) m6A 3'UTR//exon       24981863 chr1:26802014-26802015(+) m6A 3'UTR//exon       24981863 chr1:26802035-26802036(+) m6A 3'UTR//exon       24981863 chr1:26802047-26802048(+) m6A 3'UTR//exon       24981863 chr1:26802091-26802092(+) m6A 3'UTR//exon       24981863 chr1:26802228-26802229(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HMGN2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL69
Interactor2: HMGN2

Evidence Support:

Prediction-Evidence	miRanda//PITA//RNAHybrid//Targetscan
Support Database	VmiReg