Basic Information:

  VIRBase ID:  

VHID00269117

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL59:  MIMAT0029122          GSK3B:  NM_001146156     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL59	GSK3B
miRBase Accession/Entrez ID	MIMAT0029122	2932
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GSK3B	chr3:119684093(-) A-I      intronic chr3:119691343(-) A-I      intronic chr3:119779490(-) A-I      intronic chr3:119691330(-) A-I      intronic chr3:119691297(-) A-I      intronic chr3:119775870(-) A-I      intronic chr3:119639159(-) A-I      intronic chr3:119684048(-) A-I      intronic chr3:119684064(-) A-I      intronic chr3:119684114(-) A-I      intronic chr3:119775909(-) A-I      intronic chr3:119793436(-) A-I      intronic chr3:119691316(-) A-I      intronic chr3:119597197(-) A-I      intronic chr3:119805541(-) A-I      intronic chr3:119597216(-) A-I      intronic chr3:119597217(-) A-I      intronic chr3:119806297(-) A-I      intronic chr3:119639155(-) A-I      intronic chr3:119597233(-) A-I      intronic chr3:119597225(-) A-I      intronic chr3:119557067(-) A-I      intronic chr3:119800272(-) A-I      intronic chr3:119799070(-) A-I      intronic chr3:119800199(-) A-I      intronic chr3:119800222(-) A-I      intronic chr3:119788868(-) A-I      intronic chr3:119788814(-) A-I      intronic chr3:119777640(-) A-I      intronic chr3:119777636(-) A-I      intronic chr3:119744109(-) A-I      intronic chr3:119800311(-) A-I      intronic chr3:119775745(-) A-I      intronic chr3:119775411(-) A-I      intronic chr3:119775400(-) A-I      intronic chr3:119775362(-) A-I      intronic chr3:119775360(-) A-I      intronic chr3:119775355(-) A-I      intronic chr3:119775354(-) A-I      intronic chr3:119775277(-) A-I      intronic chr3:119775255(-) A-I      intronic chr3:119744047(-) A-I      intronic chr3:119556075(-) A-I      intronic chr3:119744098(-) A-I      intronic chr3:119746112(-) A-I      intronic chr3:119745494(-) A-I      intronic chr3:119745587(-) A-I      intronic chr3:119797795(-) A-I      intronic chr3:119797577(-) A-I      intronic chr3:119800325(-) A-I      intronic chr3:119801274(-) A-I      intronic chr3:119801422(-) A-I      intronic chr3:119745977(-) A-I      intronic chr3:119806872(-) A-I      intronic chr3:119797508(-) A-I      intronic chr3:119793442(-) A-I      intronic chr3:119793363(-) A-I      intronic chr3:119793336(-) A-I      intronic chr3:119793281(-) A-I      intronic chr3:119550382(-) A-I      intronic chr3:119550500(-) A-I      intronic chr3:119556064(-) A-I      intronic chr3:119793272(-) A-I      intronic chr3:119556078(-) A-I      intronic chr3:119556142(-) A-I      intronic chr3:119556890(-) A-I      intronic chr3:119556891(-) A-I      intronic chr3:119557001(-) A-I      intronic chr3:119557028(-) A-I      intronic chr3:119557054(-) A-I      intronic chr3:119557083(-) A-I      intronic chr3:119559303(-) A-I      intronic chr3:119562034(-) A-I      intronic chr3:119571320(-) A-I      intronic chr3:119639134(-) A-I      intronic chr3:119639149(-) A-I      intronic chr3:119639266(-) A-I      intronic chr3:119639281(-) A-I      intronic chr3:119640804(-) A-I      intronic chr3:119640876(-) A-I      intronic chr3:119640937(-) A-I      intronic chr3:119640938(-) A-I      intronic chr3:119640946(-) A-I      intronic chr3:119644068(-) A-I      intronic chr3:119648666(-) A-I      intronic chr3:119650363(-) A-I      intronic chr3:119651773(-) A-I      intronic chr3:119651828(-) A-I      intronic chr3:119651829(-) A-I      intronic chr3:119661269(-) A-I      intronic chr3:119661278(-) A-I      intronic chr3:119677413(-) A-I      intronic chr3:119677430(-) A-I      intronic chr3:119793065(-) A-I      intronic chr3:119806267(-) A-I      intronic chr3:119791401(-) A-I      intronic chr3:119791306(-) A-I      intronic chr3:119791296(-) A-I      intronic chr3:119791170(-) A-I      intronic chr3:119806920(-) A-I      intronic chr3:119806944(-) A-I      intronic chr3:119791148(-) A-I      intronic chr3:119788920(-) A-I      intronic chr3:119788903(-) A-I      intronic chr3:119788877(-) A-I      intronic chr3:119680309(-) A-I      intronic chr3:119677443(-) A-I      intronic chr3:119677511(-) A-I      intronic chr3:119677519(-) A-I      intronic chr3:119678667(-) A-I      intronic chr3:119792147(-) A-I      intronic chr3:119797564(-) A-I      intronic chr3:119797511(-) A-I      intronic chr3:119680327(-) A-I      intronic chr3:119680362(-) A-I      intronic chr3:119687947(-) A-I      intronic chr3:119688053(-) A-I      intronic chr3:119688056(-) A-I      intronic chr3:119691554(-) A-I      intronic chr3:119694102(-) A-I      intronic chr3:119694218(-) A-I      intronic chr3:119709531(-) A-I      intronic chr3:119714007(-) A-I      intronic chr3:119720182(-) A-I      intronic chr3:119721437(-) A-I      intronic chr3:119797953(-) A-I      intronic chr3:119798353(-) A-I      intronic chr3:119798358(-) A-I      intronic chr3:119798509(-) A-I      intronic chr3:119798946(-) A-I      intronic chr3:119798981(-) A-I      intronic chr3:119799000(-) A-I      intronic chr3:119746096(-) A-I      intronic chr3:119799043(-) A-I      intronic chr3:119799052(-) A-I      intronic chr3:119799055(-) A-I      intronic chr3:119562119(-) A-I      NonSyn:Asn->Ser chr3:119562120(-) A-I      NonSyn:Asn->Asp chr3:119797485(-) A-I      intronic chr3:119745836(-) A-I      intronic chr3:119745678(-) A-I      intronic chr3:119714723(-) A-I      intronic chr3:119640840(-) A-I      intronic chr3:119639283(-) A-I      intronic chr3:119562050(-) A-I      intronic chr3:119678500(-) A-I      intronic chr3:119714105(-) A-I      intronic chr3:119799515(-) A-I      intronic chr3:119746102(-) A-I      intronic chr3:119639306(-) A-I      intronic chr3:119797491(-) A-I      intronic chr3:119561969(-) A-I      intronic chr3:119678473(-) A-I      intronic chr3:119640821(-) A-I      intronic chr3:119561966(-) A-I      intronic chr3:119793147(-) A-I      intronic chr3:119798898(-) A-I      intronic chr3:119678458(-) A-I      intronic chr3:119678424(-) A-I      intronic chr3:119552639(-) A-I      intronic chr3:119562041(-) A-I      intronic chr3:119804527(-) A-I      intronic chr3:119682413(-) A-I      intronic chr3:119561955(-) A-I      intronic chr3:119713925(-) A-I      intronic chr3:119561927(-) A-I      intronic chr3:119677372(-) A-I      intronic chr3:119561858(-) A-I      intronic chr3:119713929(-) A-I      intronic chr3:119678543(-) A-I      intronic chr3:119712744(-) A-I      intronic chr3:119639160(-) A-I      intronic chr3:119562029(-) A-I      intronic chr3:119801416(-) A-I      intronic chr3:119678490(-) A-I      intronic chr3:119797823(-) A-I      intronic chr3:119694177(-) A-I      intronic chr3:119801407(-) A-I      intronic chr3:119746005(-) A-I      intronic chr3:119561900(-) A-I      intronic chr3:119798466(-) A-I      intronic chr3:119561911(-) A-I      intronic chr3:119797917(-) A-I      intronic chr3:119678494(-) A-I      intronic chr3:119661335(-) A-I      intronic chr3:119775990(-) A-I      intronic chr3:119561975(-) A-I      intronic chr3:119775324(-) A-I      intronic chr3:119561962(-) A-I      intronic chr3:119677486(-) A-I      intronic chr3:119678459(-) A-I      intronic chr3:119561989(-) A-I      intronic chr3:119550315(-) A-I      intronic chr3:119561923(-) A-I      intronic chr3:119775818(-) A-I      intronic chr3:119678542(-) A-I      intronic chr3:119639263(-) A-I      intronic chr3:119799546(-) A-I      intronic chr3:119561859(-) A-I      intronic chr3:119806135(-) A-I      intronic chr3:119714586(-) A-I      intronic chr3:119557012(-) A-I      intronic chr3:119562026(-) A-I      intronic chr3:119686152(-) A-I      intronic chr3:119561937(-) A-I      intronic chr3:119798367(-) A-I      intronic chr3:119797538(-) A-I      intronic chr3:119775380(-) A-I      intronic chr3:119765524(-) A-I      intronic chr3:119745501(-) A-I      intronic chr3:119557130(-) A-I      intronic chr3:119746142(-) A-I      intronic chr3:119799102(-) A-I      intronic chr3:119689362(-) A-I      intronic chr3:119798317(-) A-I      intronic chr3:119798449(-) A-I      intronic chr3:119640737(-) A-I      intronic chr3:119745507(-) A-I      intronic chr3:119799421(-) A-I      intronic chr3:119799530(-) A-I      intronic chr3:119793004(-) A-I      intronic chr3:119689414(-) A-I      intronic chr3:119746218(-) A-I      intronic chr3:119644064(-) A-I      intronic chr3:119806257(-) A-I      intronic chr3:119797576(-) A-I      intronic chr3:119745835(-) A-I      intronic chr3:119688030(-) A-I      intronic chr3:119731780(-) A-I      intronic chr3:119651765(-) A-I      intronic chr3:119714001(-) A-I      intronic chr3:119805388(-) A-I      intronic chr3:119806270(-) A-I      intronic chr3:119775263(-) A-I      intronic chr3:119806271(-) A-I      intronic chr3:119678534(-) A-I      intronic chr3:119677409(-) A-I      intronic chr3:119806340(-) A-I      intronic chr3:119806150(-) A-I      intronic chr3:119797693(-) A-I      intronic chr3:119799585(-) A-I      intronic chr3:119721457(-) A-I      intronic chr3:119798953(-) A-I      intronic chr3:119745623(-) A-I      intronic chr3:119793053(-) A-I      intronic chr3:119775283(-) A-I      intronic chr3:119805585(-) A-I      intronic chr3:119714849(-) A-I      intronic chr3:119800246(-) A-I      intronic chr3:119637231(-) A-I      intronic chr3:119637234(-) A-I      intronic chr3:119682383(-) A-I      intronic chr3:119775817(-) A-I      intronic chr3:119791358(-) A-I      intronic chr3:119745582(-) A-I      intronic chr3:119557053(-) A-I      intronic chr3:119687969(-) A-I      intronic chr3:119546361(-) A-I      intronic chr3:119691355(-) A-I      intronic chr3:119550248(-) A-I      intronic chr3:119791285(-) A-I      intronic chr3:119806995(-) A-I      intronic chr3:119775289(-) A-I      intronic chr3:119798415(-) A-I      intronic chr3:119806136(-) A-I      intronic chr3:119677348(-) A-I      intronic chr3:119639264(-) A-I      intronic chr3:119798330(-) A-I      intronic chr3:119799556(-) A-I      intronic chr3:119806829(-) A-I      intronic chr3:119800237(-) A-I      intronic chr3:119682389(-) A-I      intronic chr3:119557126(-) A-I      intronic chr3:119798950(-) A-I      intronic chr3:119682451(-) A-I      intronic chr3:119798446(-) A-I      intronic chr3:119639291(-) A-I      intronic chr3:119637248(-) A-I      intronic chr3:119800294(-) A-I      intronic chr3:119556032(-) A-I      intronic chr3:119640728(-) A-I      intronic chr3:119686907(-) A-I      intronic chr3:119775824(-) A-I      intronic chr3:119799543(-) A-I      intronic chr3:119775247(-) A-I      intronic chr3:119691487(-) A-I      intronic chr3:119807011(-) A-I      intronic chr3:119689375(-) A-I      intronic chr3:119678689(-) A-I      intronic chr3:119798420(-) A-I      intronic chr3:119720209(-) A-I      intronic chr3:119792120(-) A-I      intronic chr3:119661346(-) A-I      intronic chr3:119687075(-) A-I      intronic chr3:119745502(-) A-I      intronic chr3:119714081(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	GSK3B	chr3:119747930(-) A-I intron -    22327324 chr3:119561858(-) A-I intron -    22028664 chr3:119561859(-) A-I intron -    22028664 chr3:119561900(-) A-I intron -    22028664 chr3:119561911(-) A-I intron -    22028664 chr3:119561923(-) A-I intron -    22028664 chr3:119561927(-) A-I intron -    22028664 chr3:119561937(-) A-I intron -    22028664 chr3:119561955(-) A-I intron -    22028664 chr3:119561962(-) A-I intron -    22028664 chr3:119561966(-) A-I intron -    22028664 chr3:119561969(-) A-I intron -    22028664 chr3:119561975(-) A-I intron -    22028664 chr3:119561989(-) A-I intron -    22028664 chr3:119562026(-) A-I intron -    22028664 chr3:119562029(-) A-I intron -    22028664 chr3:119562041(-) A-I intron -    22028664 chr3:119562050(-) A-I intron -    22028664 chr3:119562119(-) A-I exon CDS    22028664 chr3:119562120(-) A-I exon CDS    22028664 chr3:119678424(-) A-I intron -    22028664 chr3:119678458(-) A-I intron -    22028664 chr3:119678459(-) A-I intron -    22028664 chr3:119678473(-) A-I intron -    22028664 chr3:119678486(-) A-I intron -    22028664 chr3:119678490(-) A-I intron -    22028664 chr3:119678494(-) A-I intron -    22028664 chr3:119678500(-) A-I intron -    22028664 chr3:119678533(-) A-I intron -    22028664 chr3:119678542(-) A-I intron -    22028664 chr3:119678543(-) A-I intron -    22028664 chr3:119543053(-) A-I exon 3'UTR    21960545 chr3:119550428(-) A-G intron -    22484847 chr3:119557012(-) A-G intron -    22484847 chr3:119557014(-) A-G intron -    22484847 chr3:119557053(-) A-G intron -    22484847 chr3:119614973(-) A-T intron -    22484847 chr3:119616659(-) C-T intron -    22484847 chr3:119627870(-) G-A intron -    22484847 chr3:119627895(-) G-A intron -    22484847 chr3:119637081(-) T-C intron -    22484847 chr3:119639160(-) A-G intron -    22484847 chr3:119639199(-) T-A intron -    22484847 chr3:119639211(-) A-G intron -    22484847 chr3:119640821(-) A-G intron -    22484847 chr3:119647451(-) G-T intron -    22484847 chr3:119651845(-) A-G intron -    22484847 chr3:119651859(-) A-G intron -    22484847 chr3:119661335(-) A-G intron -    22484847 chr3:119661341(-) A-G intron -    22484847 chr3:119661346(-) A-G intron -    22484847 chr3:119671164(-) T-C intron -    22484847 chr3:119677401(-) A-G intron -    22484847 chr3:119677409(-) A-G intron -    22484847 chr3:119677486(-) A-G intron -    22484847 chr3:119678459(-) A-G intron -    22484847 chr3:119678486(-) A-G intron -    22484847 chr3:119681222(-) G-T intron -    22484847 chr3:119682413(-) A-G intron -    22484847 chr3:119682492(-) C-T intron -    22484847 chr3:119689582(-) A-G intron -    22484847 chr3:119694177(-) A-G intron -    22484847 chr3:119713925(-) A-G intron -    22484847 chr3:119714001(-) A-G intron -    22484847 chr3:119714098(-) A-G intron -    22484847 chr3:119714105(-) A-G intron -    22484847 chr3:119740255(-) G-A intron -    22484847 chr3:119740377(-) C-T intron -    22484847 chr3:119745501(-) A-G intron -    22484847 chr3:119745502(-) A-G intron -    22484847 chr3:119745608(-) A-G intron -    22484847 chr3:119745623(-) A-G intron -    22484847 chr3:119745664(-) A-G intron -    22484847 chr3:119745818(-) A-G intron -    22484847 chr3:119745835(-) A-G intron -    22484847 chr3:119745836(-) A-G intron -    22484847 chr3:119746102(-) A-G intron -    22484847 chr3:119746141(-) A-G intron -    22484847 chr3:119746142(-) A-G intron -    22484847 chr3:119746218(-) A-G intron -    22484847 chr3:119746222(-) A-G intron -    22484847 chr3:119751490(-) A-T intron -    22484847 chr3:119765524(-) A-G intron -    22484847 chr3:119775263(-) A-G intron -    22484847 chr3:119775283(-) A-G intron -    22484847 chr3:119775289(-) A-G intron -    22484847 chr3:119775324(-) A-G intron -    22484847 chr3:119775325(-) A-G intron -    22484847 chr3:119775367(-) G-T intron -    22484847 chr3:119775380(-) A-G intron -    22484847 chr3:119775817(-) A-G intron -    22484847 chr3:119775818(-) A-G intron -    22484847 chr3:119775864(-) A-G intron -    22484847 chr3:119775880(-) A-G intron -    22484847 chr3:119775990(-) A-G intron -    22484847 chr3:119782402(-) A-G intron -    22484847 chr3:119791160(-) G-A intron -    22484847 chr3:119791285(-) A-G intron -    22484847 chr3:119791286(-) A-G intron -    22484847 chr3:119791358(-) A-G intron -    22484847 chr3:119791360(-) T-C intron -    22484847 chr3:119792120(-) A-G intron -    22484847 chr3:119792926(-) A-G intron -    22484847 chr3:119793053(-) A-G intron -    22484847 chr3:119793147(-) A-G intron -    22484847 chr3:119793323(-) A-G intron -    22484847 chr3:119797570(-) A-G intron -    22484847 chr3:119797576(-) A-G intron -    22484847 chr3:119797632(-) A-G intron -    22484847 chr3:119797693(-) A-G intron -    22484847 chr3:119798317(-) A-G intron -    22484847 chr3:119798435(-) A-G intron -    22484847 chr3:119798446(-) A-G intron -    22484847 chr3:119800228(-) A-G intron -    22484847 chr3:119800237(-) A-G intron -    22484847 chr3:119800246(-) A-G intron -    22484847 chr3:119800294(-) A-G intron -    22484847 chr3:119805450(-) A-G intron -    22484847 chr3:119806135(-) A-G intron -    22484847 chr3:119806136(-) A-G intron -    22484847 chr3:119806150(-) A-G intron -    22484847 chr3:119806212(-) A-G intron -    22484847 chr3:119806257(-) A-G intron -    22484847 chr3:119806270(-) A-G intron -    22484847 chr3:119806271(-) A-G intron -    22484847 chr3:119806340(-) A-G intron -    22484847 chr3:119806864(-) A-G intron -    22484847 chr3:119806868(-) A-G intron -    22484847 chr3:119806878(-) A-G intron -    22484847 chr3:119806883(-) T-C intron -    22484847 chr3:119806995(-) A-G intron -    22484847 chr3:119807011(-) A-G intron -    22484847 chr3:119807012(-) A-G intron -    22484847 chr3:119807020(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GSK3B	chr3:119540182-119540183(-) m6A 3'UTR       27773535 chr3:119540267-119540268(-) m6A 3'UTR       27773535 chr3:119540296-119540297(-) m6A 3'UTR       27773535 chr3:119542182-119542183(-) m6A 3'UTR       27773535 chr3:119542202-119542203(-) m6A 3'UTR       27773535 chr3:119545303-119545304(-) m6A 3'UTR       24981863 chr3:119545308-119545309(-) m6A 3'UTR       24981863 chr3:119545372-119545373(-) m6A 3'UTR       24981863 chr3:119545679-119545680(-) m6A CDS//exon       27773535 chr3:119545686-119545687(-) m6A CDS//exon       27773535 chr3:119562198-119562199(-) m6A CDS//exon//intron       27773535 chr3:119562230-119562231(-) m6A exon//intron       27773535 chr3:119562303-119562304(-) m6A exon//intron       27773535 chr3:119582297-119582298(-) m6A CDS//exon       27773535 chr3:119582314-119582315(-) m6A CDS//exon       27773535 chr3:119582327-119582328(-) m6A CDS//exon       27773535 chr3:119582436-119582437(-) m6A CDS//exon       27773535 chr3:119585457-119585458(-) m6A CDS//intron       27773535 chr3:119585462-119585463(-) m6A CDS//intron       27773535 chr3:119595264-119595265(-) m6A CDS//exon       27773535 chr3:119595308-119595309(-) m6A CDS//exon       27773535 chr3:119595314-119595315(-) m6A CDS//exon       27773535 chr3:119595345-119595346(-) m6A CDS//exon       27773535 chr3:119721028-119721029(-) m6A CDS       27371828 chr3:119721082-119721083(-) m6A CDS       24981863//27773535//27371828//22575960 chr3:119812262-119812263(-) m6A CDS       24981863//28052920//27773535//27371828//22608085 chr3:119812335-119812336(-) m6A 5'UTR       24981863//27371828//22608085 chr3:119812377-119812378(-) Y 5'UTR       26075521 chr3:119812379-119812380(-) m6A 5'UTR       24981863//27371828//22608085 chr3:119812713-119812714(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085 chr3:119813015-119813016(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr3:119813144-119813145(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	GSK3B	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL59
Interactor2: GSK3B

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg