Basic Information:

  VIRBase ID:  

VHID00264811

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US22-3p:  MIMAT0028166          NEK8:  NM_178170     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US22-3p	NEK8
miRBase Accession/Entrez ID	MIMAT0028166	284086
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	JCK//NEK12A//NPHP9//RHPD2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NEK8	chr17:27056513(+) A-I      intronic chr17:27056491(+) A-I      intronic chr17:27058830(+) A-I      intronic chr17:27057671(+) A-I      intronic chr17:27057663(+) A-I      intronic chr17:27056477(+) A-I      intronic chr17:27067155(+) A-I      intronic chr17:27067148(+) A-I      intronic chr17:27067147(+) A-I      intronic chr17:27056507(+) A-I      intronic chr17:27067272(+) A-I      intronic chr17:27067146(+) A-I      intronic chr17:27067124(+) A-I      intronic chr17:27067123(+) A-I      intronic chr17:27066717(+) A-I      intronic chr17:27061684(+) A-I      intronic chr17:27059155(+) A-I      intronic chr17:27066596(+) A-I      intronic chr17:27067195(+) A-I      intronic chr17:27066566(+) A-I      intronic chr17:27066487(+) A-I      intronic chr17:27066593(+) A-I      intronic chr17:27057677(+) A-I      intronic chr17:27066664(+) A-I      intronic chr17:27066567(+) A-I      intronic chr17:27066537(+) A-I      intronic chr17:27067065(+) A-I      intronic chr17:27067252(+) A-I      intronic chr17:27067040(+) A-I      intronic chr17:27057820(+) A-I      intronic chr17:27066606(+) A-I      intronic chr17:27066554(+) A-I      intronic chr17:27067223(+) A-I      intronic chr17:27067191(+) A-I      intronic chr17:27066592(+) A-I      intronic chr17:27057198(+) A-I      intronic chr17:27057731(+) A-I      intronic chr17:27066516(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NEK8	chr17:27066596(+) A-G intron -    22484847 chr17:27066606(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NEK8	chr17:27055816-27055817(+) m6A 5'UTR//intron       27773536 chr17:27061066-27061067(+) m6A 5'UTR//CDS//exon       - chr17:27061257-27061258(+) m6A exon//intron       - chr17:27061265-27061266(+) m6A exon//intron       - chr17:27062041-27062042(+) m6A exon//intron       - chr17:27062074-27062075(+) m6A exon//intron       - chr17:27064544-27064545(+) m6A CDS//intron       - chr17:27064614-27064615(+) m6A CDS//intron       25456834 chr17:27064732-27064733(+) m6A CDS       - chr17:27064849-27064850(+) m6A CDS       - chr17:27069885-27069886(+) m6A 3'UTR       25456834//24981863 chr17:27069914-27069915(+) m6A 3'UTR       25456834//24981863 chr17:27070139-27070140(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr17:27070185-27070186(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NEK8	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US22-3p
Interactor2: NEK8

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg