Basic Information:

  VIRBase ID:  

VHID00259434

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US4-3p:  MIMAT0026628          CMPK2:  NM_207315     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US4-3p	CMPK2
miRBase Accession/Entrez ID	MIMAT0026628	129607
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NDK//TMPK2//TYKi//UMP-CMPK2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CMPK2	chr2:6993865(-) A-I      intronic chr2:6993873(-) A-I      intronic chr2:6993209(-) A-I      intronic chr2:6993218(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CMPK2	chr2:6993844(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CMPK2	chr2:6989325-6989326(-) m6A 3'UTR//exon//intron       24981863 chr2:6989401-6989402(-) m6A 3'UTR//exon//intron       24981863 chr2:6989610-6989611(-) m6A 3'UTR//exon//intron       - chr2:6989636-6989637(-) m6A 3'UTR//exon//intron       - chr2:6989663-6989664(-) m6A 3'UTR//exon//intron       - chr2:6989678-6989679(-) m6A 3'UTR//exon//intron       - chr2:6989716-6989717(-) m6A 3'UTR//exon//intron       - chr2:6989729-6989730(-) m6A 3'UTR//exon//intron       - chr2:6991609-6991610(-) m6A CDS//exon//intron       27371828 chr2:6991626-6991627(-) m6A CDS//exon//intron       27371828 chr2:6991702-6991703(-) m6A CDS//exon//intron       27371828 chr2:6991712-6991713(-) m6A CDS//exon//intron       27371828 chr2:7006673-7006674(-) m6A exon       27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-US4-3p	Exosome B cell line (Raji)|Primary dendritic cells|T cell line (J77)     21505438
	CMPK2	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US4-3p
Interactor2: CMPK2

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg