Basic Information:

  VIRBase ID:  

VHID00257154

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US5-2-5p:  MIMAT0026553          HSPA1B:  NM_005346     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US5-2-5p	HSPA1B
miRBase Accession/Entrez ID	MIMAT0026553	3304
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HSP70-1//HSP70-1B//HSP70-2//HSP70.1//HSP70.2//HSP72//HSPA1//HSX70

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HSPA1B	chr6:31795562(+) A-I      NonSyn:Arg->Gly

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HSPA1B	chr6:31795598-31795599(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chr6:31795648-31795649(+) m6A 5'UTR       24284625//25456834//24981863//26404942//27371828//27773536//22575960//22608085 chr6:31795696-31795697(+) Cm 5'UTR       - chr6:31795896-31795897(+) m6A CDS       24981863 chr6:31795911-31795912(+) m6A CDS       24981863 chr6:31795920-31795921(+) m6A CDS       24981863 chr6:31797081-31797082(+) m6A CDS       24981863 chr6:31797423-31797424(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr6:31797431-31797432(+) m1A CDS       26863196 chr6:31797441-31797442(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr6:31797553-31797554(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:31797690-31797691(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:31797699-31797700(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:31797707-31797708(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:31797958-31797959(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HSPA1B	Exosome Blood     - Nucleolus K562 cells     - Nucleus Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US5-2-5p
Interactor2: HSPA1B

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg