Basic Information:

  VIRBase ID:  

VHID00256717

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL112-5p:  MIMAT0026552          KLF3:  NM_016531     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL112-5p	KLF3
miRBase Accession/Entrez ID	MIMAT0026552	51274
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BKLF

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	KLF3	chr4:38686366(+) A-I      intronic chr4:38686399(+) A-I      intronic chr4:38678792(+) A-I      intronic chr4:38678791(+) A-I      intronic chr4:38686416(+) A-I      intronic chr4:38683780(+) A-I      intronic chr4:38683797(+) A-I      intronic chr4:38686374(+) A-I      intronic chr4:38682476(+) A-I      intronic chr4:38683860(+) A-I      intronic chr4:38686292(+) A-I      intronic chr4:38686398(+) A-I      intronic chr4:38677942(+) A-I      intronic chr4:38677875(+) A-I      intronic chr4:38677833(+) A-I      intronic chr4:38683809(+) A-I      intronic chr4:38686397(+) A-I      intronic chr4:38682473(+) A-I      intronic chr4:38678811(+) A-I      intronic chr4:38683932(+) A-I      intronic chr4:38678656(+) A-I      intronic chr4:38683816(+) A-I      intronic chr4:38682592(+) A-I      intronic chr4:38682610(+) A-I      intronic chr4:38682507(+) A-I      intronic chr4:38687862(+) A-I      intronic chr4:38682510(+) A-I      intronic chr4:38682416(+) A-I      intronic chr4:38687811(+) A-I      intronic chr4:38688060(+) A-I      intronic chr4:38687857(+) A-I      intronic chr4:38671267(+) A-I      intronic chr4:38683711(+) A-I      intronic chr4:38683779(+) A-I      intronic chr4:38687810(+) A-I      intronic chr4:38687851(+) A-I      intronic chr4:38683773(+) A-I      intronic chr4:38678803(+) A-I      intronic chr4:38678709(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	KLF3	chr4:38682416(+) A-I intron -    15258596 chr4:38682601(+) A-I intron -    15258596 chr4:38682612(+) A-I intron -    15258596 chr4:38678709(+) A-G intron -    22484847 chr4:38682457(+) A-G intron -    22484847 chr4:38682510(+) A-G intron -    22484847 chr4:38683711(+) A-G intron -    22484847 chr4:38683773(+) A-G intron -    22484847 chr4:38683779(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KLF3	chr4:38665985-38665986(+) m6A 5'UTR//exon       24209618 chr4:38691404-38691405(+) m6A CDS       24284625//24981863//27773535 chr4:38691416-38691417(+) m6A CDS       24284625//24981863//27773535 chr4:38691426-38691427(+) m6A CDS       24284625//24981863 chr4:38691466-38691467(+) m6A CDS       24284625//24209618//24981863 chr4:38691551-38691552(+) m6A 3'UTR//intron       24284625//24209618//24981863 chr4:38696402-38696403(+) m6A CDS       24284625//24209618//24981863 chr4:38696517-38696518(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr4:38698709-38698710(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr4:38698763-38698764(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:38698772-38698773(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:38698784-38698785(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:38698799-38698800(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:38698816-38698817(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:38699026-38699027(+) m6A 3'UTR       24284625//24209618//24981863 chr4:38699085-38699086(+) m6A 3'UTR       24981863 chr4:38699100-38699101(+) m6A 3'UTR       24981863 chr4:38699135-38699136(+) m6A 3'UTR       24981863 chr4:38699168-38699169(+) m6A 3'UTR       24981863 chr4:38699176-38699177(+) m6A 3'UTR       24981863 chr4:38700589-38700590(+) m6A 3'UTR       24981863 chr4:38700674-38700675(+) m6A 3'UTR       24981863 chr4:38700720-38700721(+) m6A 3'UTR       24981863 chr4:38702566-38702567(+) m6A 3'UTR       27773535 chr4:38702573-38702574(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	KLF3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL112-5p
Interactor2: KLF3

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg