Basic Information:

  VIRBase ID:  

VHID00256642

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL112-5p:  MIMAT0026552          PHLPP1:  NM_194449     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL112-5p	PHLPP1
miRBase Accession/Entrez ID	MIMAT0026552	23239
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	PHLPP//PLEKHE1//PPM3A//SCOP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PHLPP1	chr18:60542372(+) A-I      intronic chr18:60639162(+) A-I      intronic chr18:60639119(+) A-I      intronic chr18:60639110(+) A-I      intronic chr18:60485550(+) A-I      intronic chr18:60639108(+) A-I      intronic chr18:60558960(+) A-I      intronic chr18:60558944(+) A-I      intronic chr18:60558939(+) A-I      intronic chr18:60558938(+) A-I      intronic chr18:60558937(+) A-I      intronic chr18:60558908(+) A-I      intronic chr18:60516819(+) A-I      intronic chr18:60485580(+) A-I      intronic chr18:60558961(+) A-I      intronic chr18:60485563(+) A-I      intronic chr18:60558894(+) A-I      intronic chr18:60555888(+) A-I      intronic chr18:60555672(+) A-I      intronic chr18:60553656(+) A-I      intronic chr18:60553643(+) A-I      intronic chr18:60546810(+) A-I      intronic chr18:60543150(+) A-I      intronic chr18:60543149(+) A-I      intronic chr18:60396675(+) A-I      intronic chr18:60395408(+) A-I      intronic chr18:60395399(+) A-I      intronic chr18:60395265(+) A-I      intronic chr18:60395256(+) A-I      intronic chr18:60394394(+) A-I      intronic chr18:60394314(+) A-I      intronic chr18:60394311(+) A-I      intronic chr18:60537243(+) A-I      intronic chr18:60394302(+) A-I      intronic chr18:60393894(+) A-I      intronic chr18:60393872(+) A-I      intronic chr18:60393860(+) A-I      intronic chr18:60392416(+) A-I      intronic chr18:60516796(+) A-I      intronic chr18:60522127(+) A-I      intronic chr18:60483680(+) A-I      intronic chr18:60485115(+) A-I      intronic chr18:60485120(+) A-I      intronic chr18:60485168(+) A-I      intronic chr18:60522150(+) A-I      intronic chr18:60522166(+) A-I      intronic chr18:60525985(+) A-I      intronic chr18:60530683(+) A-I      intronic chr18:60559015(+) A-I      intronic chr18:60532286(+) A-I      intronic chr18:60462449(+) A-I      intronic chr18:60442555(+) A-I      intronic chr18:60532299(+) A-I      intronic chr18:60614135(+) A-I      intronic chr18:60535669(+) A-I      intronic chr18:60535692(+) A-I      intronic chr18:60488410(+) A-I      intronic chr18:60488438(+) A-I      intronic chr18:60490643(+) A-I      intronic chr18:60490676(+) A-I      intronic chr18:60429912(+) A-I      intronic chr18:60429847(+) A-I      intronic chr18:60428768(+) A-I      intronic chr18:60428616(+) A-I      intronic chr18:60428232(+) A-I      intronic chr18:60419410(+) A-I      intronic chr18:60490742(+) A-I      intronic chr18:60537225(+) A-I      intronic chr18:60494035(+) A-I      intronic chr18:60494215(+) A-I      intronic chr18:60506800(+) A-I      intronic chr18:60485188(+) A-I      intronic chr18:60485192(+) A-I      intronic chr18:60485339(+) A-I      intronic chr18:60485526(+) A-I      intronic chr18:60485562(+) A-I      intronic chr18:60402555(+) A-I      intronic chr18:60538971(+) A-I      intronic chr18:60506805(+) A-I      intronic chr18:60506809(+) A-I      intronic chr18:60402537(+) A-I      intronic chr18:60394301(+) A-I      intronic chr18:60539058(+) A-I      intronic chr18:60515809(+) A-I      intronic chr18:60515827(+) A-I      intronic chr18:60542353(+) A-I      intronic chr18:60485587(+) A-I      intronic chr18:60485588(+) A-I      intronic chr18:60632818(+) A-I      intronic chr18:60543027(+) A-I      intronic chr18:60515944(+) A-I      intronic chr18:60516723(+) A-I      intronic chr18:60516732(+) A-I      intronic chr18:60516783(+) A-I      intronic chr18:60543066(+) A-I      intronic chr18:60402414(+) A-I      intronic chr18:60397845(+) A-I      intronic chr18:60396698(+) A-I      intronic chr18:60558898(+) A-I      intronic chr18:60558913(+) A-I      intronic chr18:60558921(+) A-I      intronic chr18:60559011(+) A-I      intronic chr18:60639224(+) A-I      intronic chr18:60639148(+) A-I      intronic chr18:60637918(+) A-I      intronic chr18:60635266(+) A-I      intronic chr18:60635186(+) A-I      intronic chr18:60635161(+) A-I      intronic chr18:60635158(+) A-I      intronic chr18:60632878(+) A-I      intronic chr18:60632800(+) A-I      intronic chr18:60628422(+) A-I      intronic chr18:60628414(+) A-I      intronic chr18:60619409(+) A-I      intronic chr18:60619385(+) A-I      intronic chr18:60614053(+) A-I      intronic chr18:60613525(+) A-I      intronic chr18:60589439(+) A-I      intronic chr18:60564983(+) A-I      intronic chr18:60564857(+) A-I      intronic chr18:60560352(+) A-I      intronic chr18:60560091(+) A-I      intronic chr18:60560050(+) A-I      intronic chr18:60559067(+) A-I      intronic chr18:60635324(+) A-I      intronic chr18:60394660(+) A-I      intronic chr18:60395381(+) A-I      intronic chr18:60459922(+) A-I      intronic chr18:60396014(+) A-I      intronic chr18:60504037(+) A-I      intronic chr18:60560375(+) A-I      intronic chr18:60395341(+) A-I      intronic chr18:60488454(+) A-I      intronic chr18:60503528(+) A-I      intronic chr18:60515863(+) A-I      intronic chr18:60394091(+) A-I      intronic chr18:60476814(+) A-I      intronic chr18:60488702(+) A-I      intronic chr18:60395881(+) A-I      intronic chr18:60395303(+) A-I      intronic chr18:60639006(+) A-I      intronic chr18:60540010(+) A-I      intronic chr18:60488623(+) A-I      intronic chr18:60488661(+) A-I      intronic chr18:60558701(+) A-I      intronic chr18:60637833(+) A-I      intronic chr18:60618308(+) A-I      intronic chr18:60490743(+) A-I      intronic chr18:60402417(+) A-I      intronic chr18:60405492(+) A-I      intronic chr18:60395508(+) A-I      intronic chr18:60559051(+) A-I      intronic chr18:60525910(+) A-I      intronic chr18:60395342(+) A-I      intronic chr18:60502594(+) A-I      intronic chr18:60516639(+) A-I      intronic chr18:60561613(+) A-I      intronic chr18:60553688(+) A-I      intronic chr18:60541367(+) A-I      intronic chr18:60555709(+) A-I      intronic chr18:60489268(+) A-I      intronic chr18:60490615(+) A-I      intronic chr18:60419328(+) A-I      intronic chr18:60438327(+) A-I      intronic chr18:60487036(+) A-I      intronic chr18:60491286(+) A-I      intronic chr18:60395352(+) A-I      intronic chr18:60489085(+) A-I      intronic chr18:60620057(+) A-I      intronic chr18:60394758(+) A-I      intronic chr18:60509734(+) A-I      intronic chr18:60428745(+) A-I      intronic chr18:60516938(+) A-I      intronic chr18:60485285(+) A-I      intronic chr18:60541555(+) A-I      intronic chr18:60488697(+) A-I      intronic chr18:60486959(+) A-I      intronic chr18:60535626(+) A-I      intronic chr18:60488653(+) A-I      intronic chr18:60637835(+) A-I      intronic chr18:60394769(+) A-I      intronic chr18:60489131(+) A-I      intronic chr18:60462590(+) A-I      intronic chr18:60639054(+) A-I      intronic chr18:60559005(+) A-I      intronic chr18:60476850(+) A-I      intronic chr18:60546784(+) A-I      intronic chr18:60542394(+) A-I      intronic chr18:60483607(+) A-I      intronic chr18:60537333(+) A-I      intronic chr18:60558818(+) A-I      intronic chr18:60438296(+) A-I      intronic chr18:60539075(+) A-I      intronic chr18:60619410(+) A-I      intronic chr18:60618421(+) A-I      intronic chr18:60500448(+) A-I      intronic chr18:60428610(+) A-I      intronic chr18:60394382(+) A-I      intronic chr18:60490670(+) A-I      intronic chr18:60471717(+) A-I      intronic chr18:60503153(+) A-I      intronic chr18:60395859(+) A-I      intronic chr18:60394700(+) A-I      intronic chr18:60541269(+) A-I      intronic chr18:60395366(+) A-I      intronic chr18:60395377(+) A-I      intronic chr18:60490611(+) A-I      intronic chr18:60428187(+) A-I      intronic chr18:60635290(+) A-I      intronic chr18:60500424(+) A-I      intronic chr18:60555034(+) A-I      intronic chr18:60561493(+) A-I      intronic chr18:60558979(+) A-I      intronic chr18:60539749(+) A-I      intronic chr18:60614165(+) A-I      intronic chr18:60438286(+) A-I      intronic chr18:60532484(+) A-I      intronic chr18:60428611(+) A-I      intronic chr18:60620060(+) A-I      intronic chr18:60485639(+) A-I      intronic chr18:60486935(+) A-I      intronic chr18:60637883(+) A-I      intronic chr18:60395947(+) A-I      intronic chr18:60560440(+) A-I      intronic chr18:60490543(+) A-I      intronic chr18:60546848(+) A-I      intronic chr18:60488714(+) A-I      intronic chr18:60615097(+) A-I      intronic chr18:60539007(+) A-I      intronic chr18:60639189(+) A-I      intronic chr18:60558889(+) A-I      intronic chr18:60552813(+) A-I      intronic chr18:60395318(+) A-I      intronic chr18:60637794(+) A-I      intronic chr18:60484314(+) A-I      intronic chr18:60538744(+) A-I      intronic chr18:60488646(+) A-I      intronic chr18:60614136(+) A-I      intronic chr18:60542288(+) A-I      intronic chr18:60561498(+) A-I      intronic chr18:60619403(+) A-I      intronic chr18:60628372(+) A-I      intronic chr18:60519333(+) A-I      intronic chr18:60628469(+) A-I      intronic chr18:60487116(+) A-I      intronic chr18:60525757(+) A-I      intronic chr18:60519171(+) A-I      intronic chr18:60541554(+) A-I      intronic chr18:60635875(+) A-I      intronic chr18:60567432(+) A-I      intronic chr18:60559075(+) A-I      intronic chr18:60619404(+) A-I      intronic chr18:60402342(+) A-I      intronic chr18:60395939(+) A-I      intronic chr18:60555007(+) A-I      intronic chr18:60539152(+) A-I      intronic chr18:60394402(+) A-I      intronic chr18:60395964(+) A-I      intronic chr18:60635228(+) A-I      intronic chr18:60585262(+) A-I      intronic chr18:60395925(+) A-I      intronic chr18:60598265(+) A-I      intronic chr18:60615139(+) A-I      intronic chr18:60402552(+) A-I      intronic chr18:60503465(+) A-I      intronic chr18:60539061(+) A-I      intronic chr18:60553640(+) A-I      intronic chr18:60635955(+) A-I      intronic chr18:60613638(+) A-I      intronic chr18:60585183(+) A-I      intronic chr18:60503288(+) A-I      intronic chr18:60521994(+) A-I      intronic chr18:60639239(+) A-I      intronic chr18:60614139(+) A-I      intronic chr18:60540041(+) A-I      intronic chr18:60532357(+) A-I      intronic chr18:60532425(+) A-I      intronic chr18:60637887(+) A-I      intronic chr18:60431240(+) A-I      intronic chr18:60491179(+) A-I      intronic chr18:60497601(+) A-I      intronic chr18:60515962(+) A-I      intronic chr18:60485509(+) A-I      intronic chr18:60639105(+) A-I      intronic chr18:60585273(+) A-I      intronic chr18:60538779(+) A-I      intronic chr18:60637845(+) A-I      intronic chr18:60585160(+) A-I      intronic chr18:60515727(+) A-I      intronic chr18:60393946(+) A-I      intronic chr18:60516974(+) A-I      intronic chr18:60484287(+) A-I      intronic chr18:60476761(+) A-I      intronic chr18:60417168(+) A-I      intronic chr18:60395463(+) A-I      intronic chr18:60535708(+) A-I      intronic chr18:60402546(+) A-I      intronic chr18:60396020(+) A-I      intronic chr18:60488440(+) A-I      intronic chr18:60488727(+) A-I      intronic chr18:60488742(+) A-I      intronic chr18:60489088(+) A-I      intronic chr18:60560414(+) A-I      intronic chr18:60395264(+) A-I      intronic chr18:60488443(+) A-I      intronic chr18:60442515(+) A-I      intronic chr18:60613551(+) A-I      intronic chr18:60503279(+) A-I      intronic chr18:60637891(+) A-I      intronic chr18:60500411(+) A-I      intronic chr18:60628380(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PHLPP1	chr18:60637845(+) A-I intron -    15342557 chr18:60637848(+) A-I intron -    15342557 chr18:60637883(+) A-I intron -    15342557 chr18:60637887(+) A-I intron -    15342557 chr18:60637891(+) A-I intron -    15342557 chr18:60637910(+) A-I intron -    15342557 chr18:60637913(+) A-I intron -    15342557 chr18:60637930(+) A-I intron -    15342557 chr18:60639239(+) A-I intron -    15342557

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PHLPP1	chr18:60382738-60382739(+) m6A 5'UTR       25456834//24981863 chr18:60382746-60382747(+) m6A 5'UTR       25456834//24981863 chr18:60382971-60382972(+) m6A CDS       25456834 chr18:60383433-60383434(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60383487-60383488(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60383493-60383494(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60383586-60383587(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60383701-60383702(+) m6A CDS       25456834//22575960 chr18:60383748-60383749(+) m6A CDS       25456834 chr18:60383880-60383881(+) m6A CDS       25456834//24981863//22608085 chr18:60384006-60384007(+) m6A CDS       25456834//22608085 chr18:60384350-60384351(+) m6A CDS       24284625//25456834//24981863//22608085 chr18:60384456-60384457(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60446698-60446699(+) m6A exon//intron       25456834//22608085 chr18:60645642-60645643(+) m6A CDS       24284625 chr18:60645789-60645790(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60645867-60645868(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr18:60646026-60646027(+) m6A CDS       24284625 chr18:60646212-60646213(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr18:60646246-60646247(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr18:60646341-60646342(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr18:60646358-60646359(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr18:60646629-60646630(+) m6A CDS       24284625//24209618//24981863//22608085 chr18:60646689-60646690(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr18:60646703-60646704(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr18:60646737-60646738(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr18:60646769-60646770(+) m6A 3'UTR       24284625//24209618//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PHLPP1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL112-5p
Interactor2: PHLPP1

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg