Basic Information:

  VIRBase ID:  

VHID00250523

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          AGRN:  NM_198576     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	AGRN
miRBase Accession/Entrez ID	MIMAT0003343	375790
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AGRIN//CMS8//CMSPPD

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	AGRN	chr1:984058(+) A-I      intronic chr1:984161(+) A-I      intronic chr1:984162(+) A-I      intronic chr1:984160(+) A-I      intronic chr1:971924(+) A-I      intronic chr1:984000(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	AGRN	chr1:955639-955640(+) m6A 5'UTR//CDS       24284625//24209618//22575960 chr1:955724-955725(+) m6A 5'UTR//CDS       24284625//22575960 chr1:957611-957612(+) m6A 5'UTR//CDS       24284625//22575960 chr1:957674-957675(+) m6A 5'UTR//CDS       24284625//22575960 chr1:957710-957711(+) m6A 5'UTR//CDS       24284625//22575960 chr1:957731-957732(+) m6A 5'UTR//CDS       24284625//22575960 chr1:957812-957813(+) m6A CDS       22575960 chr1:969612-969613(+) m6A exon//intron       25456834 chr1:969758-969759(+) m6A exon//intron       25456834 chr1:969770-969771(+) m6A exon//intron       25456834 chr1:969801-969802(+) m6A exon//intron       25456834 chr1:970667-970668(+) m6A CDS//exon       24284625 chr1:976561-976562(+) m6A CDS//exon       22575960 chr1:976671-976672(+) m6A CDS//exon       22575960 chr1:976905-976906(+) m6A CDS       24284625//22575960 chr1:978829-978830(+) m6A CDS       24284625//22575960 chr1:978961-978962(+) m6A CDS       24284625//22575960 chr1:979104-979105(+) m6A CDS       24284625//22575960 chr1:979204-979205(+) m6A CDS       24284625//22575960 chr1:979363-979364(+) m6A CDS       24284625//22575960 chr1:979578-979579(+) m6A CDS       24284625//22575960 chr1:980612-980613(+) m6A CDS       22575960 chr1:980861-980862(+) m6A CDS//exon       24284625//22575960 chr1:981179-981180(+) Y CDS//exon       25219674 chr1:981197-981198(+) m6A CDS//exon       24284625//22575960 chr1:981587-981588(+) m6A CDS//exon       24284625//22575960 chr1:981672-981673(+) m6A exon//intron       24284625//22575960 chr1:981910-981911(+) m6A CDS       24284625//22575960 chr1:981940-981941(+) m6A CDS       22575960 chr1:981961-981962(+) m6A CDS       22575960 chr1:982074-982075(+) m6A CDS       24981863//22575960 chr1:982085-982086(+) m6A CDS       24981863//22575960 chr1:983269-983270(+) m6A CDS       24284625//22575960 chr1:983540-983541(+) m6A CDS       24284625//24981863//22575960 chr1:983666-983667(+) m6A CDS       24284625//25456834//24981863//22575960 chr1:983676-983677(+) m6A CDS       24284625//25456834//24981863//22575960 chr1:983951-983952(+) m6A exon//intron       24284625//25456834 chr1:983972-983973(+) m6A exon//intron       24284625//25456834 chr1:984396-984397(+) m6A CDS//exon       - chr1:984736-984737(+) m6A CDS//exon       22575960 chr1:984785-984786(+) m6A CDS       22575960 chr1:984791-984792(+) m6A CDS       22575960 chr1:984818-984819(+) m6A CDS       22575960 chr1:984958-984959(+) m6A CDS       22575960 chr1:985079-985080(+) m6A CDS       22575960 chr1:985127-985128(+) m6A CDS       22575960 chr1:985413-985414(+) m6A CDS       24284625//22575960 chr1:985702-985703(+) m6A CDS       24284625//22575960 chr1:985895-985896(+) m6A CDS       24284625//22575960 chr1:985919-985920(+) m6A CDS       24284625//22575960 chr1:986136-986137(+) m6A CDS       22575960 chr1:986900-986901(+) Y CDS       26075521 chr1:987008-987009(+) m6A CDS       24284625//22575960 chr1:987160-987161(+) m6A CDS       24284625//22575960 chr1:987190-987191(+) Gm CDS       - chr1:987375-987376(+) m6A CDS//exon//intron       24284625//22575960 chr1:987483-987484(+) m6A exon//intron       24284625 chr1:988102-988103(+) m6A exon//intron       - chr1:988194-988195(+) m6A exon//intron       - chr1:988259-988260(+) m6A exon//intron       - chr1:988341-988342(+) m6A exon//intron       - chr1:988900-988901(+) m6A exon//intron       - chr1:989162-989163(+) m6A CDS//exon       24284625//25456834//22575960 chr1:989230-989231(+) m6A CDS//exon       24284625//22575960 chr1:989907-989908(+) m6A CDS//exon       24284625//22575960 chr1:990410-990411(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990459-990460(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990503-990504(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990526-990527(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990575-990576(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990689-990690(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:990845-990846(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:990926-990927(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:991321-991322(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:991397-991398(+) m6A 3'UTR//exon       24284625//24209618//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	AGRN	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: AGRN

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg