Basic Information:

  VIRBase ID:  

VHID00250150

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          CRTC2:  NM_181715     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	CRTC2
miRBase Accession/Entrez ID	MIMAT0003343	200186
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	TORC-2//TORC2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CRTC2	chr1:153922573(-) A-I      intronic chr1:153922324(-) A-I      intronic chr1:153922684(-) A-I      intronic chr1:153922662(-) A-I      intronic chr1:153922661(-) A-I      intronic chr1:153922216(-) A-I      intronic chr1:153922225(-) A-I      intronic chr1:153922517(-) A-I      intronic chr1:153922569(-) A-I      intronic chr1:153922547(-) A-I      intronic chr1:153922238(-) A-I      intronic chr1:153922157(-) A-I      intronic chr1:153922625(-) A-I      intronic chr1:153922530(-) A-I      intronic chr1:153922263(-) A-I      intronic chr1:153922067(-) A-I      intronic chr1:153922487(-) A-I      intronic chr1:153922243(-) A-I      intronic chr1:153922670(-) A-I      intronic chr1:153922145(-) A-I      intronic chr1:153922079(-) A-I      intronic chr1:153922159(-) A-I      intronic chr1:153922603(-) A-I      intronic chr1:153922581(-) A-I      intronic chr1:153922120(-) A-I      intronic chr1:153922511(-) A-I      intronic chr1:153922242(-) A-I      intronic chr1:153922626(-) A-I      intronic chr1:153922444(-) A-I      intronic chr1:153922203(-) A-I      intronic chr1:153922464(-) A-I      intronic chr1:153922080(-) A-I      intronic chr1:153922133(-) A-I      intronic chr1:153922627(-) A-I      intronic chr1:153922239(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CRTC2	chr1:153922079(-) A-G intron -    22484847 chr1:153922145(-) A-G intron -    22484847 chr1:153922157(-) A-G intron -    22484847 chr1:153922159(-) A-G intron -    22484847 chr1:153922225(-) A-G intron -    22484847 chr1:153922238(-) A-G intron -    22484847 chr1:153922239(-) A-G intron -    22484847 chr1:153922242(-) A-G intron -    22484847 chr1:153922243(-) A-G intron -    22484847 chr1:153922263(-) A-G intron -    22484847 chr1:153922511(-) A-G intron -    22484847 chr1:153922627(-) A-G intron -    22484847 chr1:153925631(-) G-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CRTC2	chr1:153920150-153920151(-) m6A 3'UTR       27773535 chr1:153920349-153920350(-) m6A 3'UTR//exon       24284625//25456834//28052920//27773535//27371828 chr1:153920384-153920385(-) m6A 3'UTR//exon       24284625//25456834//28052920//27773535//27371828//22575960 chr1:153920504-153920505(-) m6A 3'UTR//exon       24284625//25456834//24981863//28052920//27773535//27371828//22608085 chr1:153920660-153920661(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828 chr1:153920983-153920984(-) m6A 3'UTR//CDS//exon       27773535 chr1:153921667-153921668(-) m6A 3'UTR//CDS//exon       27773535 chr1:153921836-153921837(-) m6A 3'UTR//CDS//exon       24284625//27773535 chr1:153923780-153923781(-) m6A 3'UTR//CDS//exon//intron       24284625//27773535 chr1:153924140-153924141(-) m6A 3'UTR//CDS//exon//intron       24284625//24981863//27773535//27371828 chr1:153924604-153924605(-) m6A 3'UTR//CDS//exon//intron       24284625//24209618//24981863//28052920//27773535//27371828 chr1:153924615-153924616(-) m6A 3'UTR//CDS//exon//intron       24284625//24981863//28052920//27773535//27371828 chr1:153924681-153924682(-) m6A 3'UTR//CDS//exon//intron       24284625//24981863//27773535 chr1:153925806-153925807(-) m6A 3'UTR//CDS//exon//intron       27773535 chr1:153927627-153927628(-) m6A CDS//exon//intron       - chr1:153930631-153930632(-) m6A exon//intron       - chr1:153930637-153930638(-) m6A exon//intron       - chr1:153930656-153930657(-) m1A exon//intron       26863196 chr1:153930836-153930837(-) m6A CDS//exon//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CRTC2	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: CRTC2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg