Basic Information:

  VIRBase ID:  

VHID00248979

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          SRD5A3:  NM_024592     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	SRD5A3
miRBase Accession/Entrez ID	MIMAT0003343	79644
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CDG1P//CDG1Q//KRIZI//SRD5A2L//SRD5A2L1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SRD5A3	chr4:56235031(+) A-I      intronic chr4:56234986(+) A-I      intronic chr4:56234980(+) A-I      intronic chr4:56229099(+) A-I      intronic chr4:56229037(+) A-I      intronic chr4:56227424(+) A-I      intronic chr4:56217270(+) A-I      intronic chr4:56227448(+) A-I      intronic chr4:56227575(+) A-I      intronic chr4:56226949(+) A-I      intronic chr4:56227439(+) A-I      intronic chr4:56227440(+) A-I      intronic chr4:56227443(+) A-I      intronic chr4:56227447(+) A-I      intronic chr4:56226601(+) A-I      intronic chr4:56227574(+) A-I      intronic chr4:56229039(+) A-I      intronic chr4:56227697(+) A-I      intronic chr4:56229178(+) A-I      intronic chr4:56229179(+) A-I      intronic chr4:56235006(+) A-I      intronic chr4:56215253(+) A-I      intronic chr4:56230717(+) A-I      intronic chr4:56230713(+) A-I      intronic chr4:56229495(+) A-I      intronic chr4:56229479(+) A-I      intronic chr4:56235035(+) A-I      intronic chr4:56215271(+) A-I      intronic chr4:56217296(+) A-I      intronic chr4:56217756(+) A-I      intronic chr4:56226579(+) A-I      intronic chr4:56226615(+) A-I      intronic chr4:56226912(+) A-I      intronic chr4:56226920(+) A-I      intronic chr4:56226930(+) A-I      intronic chr4:56236991(+) A-I      3'UTR chr4:56238031(+) A-I      3'UTR chr4:56238013(+) A-I      3'UTR chr4:56238011(+) A-I      3'UTR chr4:56237969(+) A-I      3'UTR chr4:56237961(+) A-I      3'UTR chr4:56237951(+) A-I      3'UTR chr4:56237948(+) A-I      3'UTR chr4:56237947(+) A-I      3'UTR chr4:56237939(+) A-I      3'UTR chr4:56237894(+) A-I      3'UTR chr4:56237870(+) A-I      3'UTR chr4:56237851(+) A-I      3'UTR chr4:56237839(+) A-I      3'UTR chr4:56237042(+) A-I      3'UTR chr4:56237000(+) A-I      3'UTR chr4:56236995(+) A-I      3'UTR chr4:56236989(+) A-I      3'UTR chr4:56236983(+) A-I      3'UTR chr4:56236932(+) A-I      3'UTR chr4:56236926(+) A-I      3'UTR chr4:56236918(+) A-I      3'UTR chr4:56236916(+) A-I      3'UTR chr4:56236850(+) A-I      3'UTR chr4:56236847(+) A-I      3'UTR chr4:56236845(+) A-I      3'UTR chr4:56236839(+) A-I      3'UTR chr4:56236837(+) A-I      3'UTR chr4:56236821(+) A-I      3'UTR chr4:56236812(+) A-I      3'UTR chr4:56236791(+) A-I      3'UTR chr4:56236783(+) A-I      3'UTR chr4:56236781(+) A-I      3'UTR chr4:56236774(+) A-I      3'UTR chr4:56236904(+) A-I      3'UTR chr4:56237983(+) A-I      3'UTR chr4:56237963(+) A-I      3'UTR chr4:56236975(+) A-I      3'UTR chr4:56236970(+) A-I      3'UTR chr4:56236962(+) A-I      3'UTR chr4:56236952(+) A-I      3'UTR chr4:56236900(+) A-I      3'UTR chr4:56236796(+) A-I      3'UTR chr4:56238104(+) A-I      3'UTR chr4:56238096(+) A-I      3'UTR chr4:56238084(+) A-I      3'UTR chr4:56238083(+) A-I      3'UTR chr4:56238082(+) A-I      3'UTR chr4:56238065(+) A-I      3'UTR chr4:56238042(+) A-I      3'UTR chr4:56227824(+) A-I      intronic chr4:56227707(+) A-I      intronic chr4:56227502(+) A-I      intronic chr4:56216478(+) A-I      intronic chr4:56229248(+) A-I      intronic chr4:56227038(+) A-I      intronic chr4:56227119(+) A-I      intronic chr4:56229498(+) A-I      intronic chr4:56226618(+) A-I      intronic chr4:56226585(+) A-I      intronic chr4:56228460(+) A-I      intronic chr4:56229253(+) A-I      intronic chr4:56227915(+) A-I      intronic chr4:56228774(+) A-I      intronic chr4:56216322(+) A-I      intronic chr4:56227768(+) A-I      intronic chr4:56229392(+) A-I      intronic chr4:56229142(+) A-I      intronic chr4:56228769(+) A-I      intronic chr4:56227896(+) A-I      intronic chr4:56227864(+) A-I      intronic chr4:56217507(+) A-I      intronic chr4:56227493(+) A-I      intronic chr4:56221575(+) A-I      intronic chr4:56227880(+) A-I      intronic chr4:56227581(+) A-I      intronic chr4:56229275(+) A-I      intronic chr4:56227711(+) A-I      intronic chr4:56224600(+) A-I      intronic chr4:56228751(+) A-I      intronic chr4:56229087(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SRD5A3	chr4:56223974(+) A-I intron -    21960545 chr4:56224019(+) A-I intron -    21960545 chr4:56224459(+) A-I intron -    21960545 chr4:56236837(+) A-G intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SRD5A3	chr4:56212416-56212417(+) m6A 5'UTR       24981863 chr4:56212540-56212541(+) m6A CDS       24981863 chr4:56236284-56236285(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236311-56236312(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236359-56236360(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236510-56236511(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236538-56236539(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236564-56236565(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236576-56236577(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236591-56236592(+) m6A 3'UTR       24284625//24981863//22608085 chr4:56236681-56236682(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr4:56237213-56237214(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SRD5A3	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: SRD5A3

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg