Basic Information:

  VIRBase ID:  

VHID00248939

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          CCDC28B:  NM_001301011     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	CCDC28B
miRBase Accession/Entrez ID	MIMAT0003343	79140
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCDC28B	chr1:32667914(+) A-I      intronic chr1:32668980(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCDC28B	chr1:32666207-32666208(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr1:32666271-32666272(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr1:32666295-32666296(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr1:32666302-32666303(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr1:32667365-32667366(+) m6A exon//intron       25456834 chr1:32667655-32667656(+) m6A CDS//exon       24284625 chr1:32667831-32667832(+) m6A CDS//intron       - chr1:32669938-32669939(+) m1A 3'UTR//CDS//intron       26863410//26863196 chr1:32669941-32669942(+) m6A 3'UTR//CDS//intron       24981863 chr1:32669963-32669964(+) m6A 3'UTR//CDS//intron       24981863 chr1:32670205-32670206(+) m6A 3'UTR//CDS//exon       24981863 chr1:32670237-32670238(+) m6A CDS//intron       - chr1:32670891-32670892(+) m6A 3'UTR       - chr1:32670908-32670909(+) m6A 3'UTR       - chr1:32670972-32670973(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CCDC28B	Exosome Blood     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: CCDC28B

Evidence Support:

Prediction-Evidence	PITA//RNAHybrid
Support Database	VmiReg