Basic Information:

  VIRBase ID:  

VHID00248246

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          LAMTOR1:  NM_017907     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	LAMTOR1
miRBase Accession/Entrez ID	MIMAT0003343	55004
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C11orf59//p18//p27RF-Rho//PDRO//Ragulator1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LAMTOR1	chr11:71807399(-) A-I      intronic chr11:71807400(-) A-I      intronic chr11:71807422(-) A-I      intronic chr11:71807421(-) A-I      intronic chr11:71807398(-) A-I      intronic chr11:71802904(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LAMTOR1	chr11:71808562-71808563(-) m6A 3'UTR//intron       25456834//26404942//27371828//27773536 chr11:71808636-71808637(-) m6A 3'UTR//intron       25456834//24981863//26404942//27371828//27773536 chr11:71808682-71808683(-) m6A 3'UTR//intron       25456834//24981863//26404942 chr11:71808692-71808693(-) m6A 3'UTR//intron       25456834//24981863//26404942 chr11:71808850-71808851(-) m6A 3'UTR//intron       - chr11:71809586-71809587(-) m6A exon//intron       27371828//27773536 chr11:71809709-71809710(-) m6A exon//intron       27371828 chr11:71809844-71809845(-) m6A CDS//exon       27371828//27773536 chr11:71809877-71809878(-) m6A CDS//exon       27773535//27371828//27773536 chr11:71810163-71810164(-) m6A CDS//exon       27773535//27371828//27773536 chr11:71810273-71810274(-) m6A CDS//exon       24284625//24981863//27773535//27371828//27773536 chr11:71810300-71810301(-) m6A CDS//exon//intron       24284625//24981863//27773535//27371828//27773536//22575960 chr11:71811727-71811728(-) m6A exon//intron       24284625//24981863//27773535//27371828//27773536//22575960 chr11:71811735-71811736(-) m6A exon//intron       24284625//24981863//27371828//27773536//22575960 chr11:71814232-71814233(-) m6A CDS//exon//intron       24284625//25456834//24981863//27371828//27773536//22575960 chr11:71814238-71814239(-) m6A CDS//exon//intron       24284625//25456834//24981863//27371828//27773536//22575960 chr11:71814398-71814399(-) m6A 5'UTR       24209618//25456834//24981863//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	LAMTOR1	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: LAMTOR1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg