Basic Information:

  VIRBase ID:  

VHID00247619

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          DNPEP:  NR_134970     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	DNPEP
miRBase Accession/Entrez ID	MIMAT0003343	23549
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ASPEP//DAP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DNPEP	chr2:220238301(-) A-I      3'UTR chr2:220238252(-) A-I      3'UTR chr2:220238251(-) A-I      3'UTR chr2:220238314(-) A-I      3'UTR chr2:220238238(-) A-I      3'UTR chr2:220238230(-) A-I      3'UTR chr2:220238337(-) A-I      3'UTR chr2:220238319(-) A-I      3'UTR chr2:220238226(-) A-I      3'UTR chr2:220238203(-) A-I      3'UTR chr2:220238179(-) A-I      intronic chr2:220238197(-) A-I      3'UTR chr2:220238193(-) A-I      3'UTR chr2:220463935(-) A-I      intronic chr2:220456757(-) A-I      intronic chr2:220367979(-) A-I      intronic chr2:220240457(-) A-I      intronic chr2:220456783(-) A-I      intronic chr2:220456769(-) A-I      intronic chr2:220238206(-) A-I      3'UTR chr2:220238257(-) A-I      3'UTR chr2:220238210(-) A-I      3'UTR chr2:220238249(-) A-I      3'UTR chr2:220238291(-) A-I      3'UTR chr2:220238307(-) A-I      3'UTR chr2:220238219(-) A-I      3'UTR chr2:220238242(-) A-I      3'UTR chr2:220238333(-) A-I      3'UTR chr2:220243777(-) A-I      intronic chr2:220485912(-) A-I      intronic chr2:220241933(-) A-I      intronic chr2:220249300(-) A-I      intronic chr2:220240558(-) A-I      intronic chr2:220240442(-) A-I      intronic chr2:220240422(-) A-I      intronic chr2:220238185(-) A-I      3'UTR chr2:220238360(-) A-I      3'UTR chr2:220238220(-) A-I      3'UTR chr2:220238306(-) A-I      3'UTR chr2:220238338(-) A-I      3'UTR chr2:220444484(-) A-I      intronic chr2:220240515(-) A-I      intronic chr2:220241957(-) A-I      intronic chr2:220241913(-) A-I      intronic chr2:220241030(-) A-I      intronic chr2:220245161(-) A-I      intronic chr2:220242484(-) A-I      intronic chr2:220485942(-) A-I      intronic chr2:220244521(-) A-I      intronic chr2:220241088(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DNPEP	chr2:220238246(-) A-G exon 3'UTR    22484847 chr2:220240563(-) A-G intron -    22484847 chr2:220241030(-) A-G intron -    22484847 chr2:220243777(-) A-G intron -    22484847 chr2:220244521(-) A-G intron -    22484847 chr2:220245161(-) A-G intron -    22484847 chr2:220249299(-) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DNPEP	chr2:220238572-220238573(-) m6A 3'UTR       27773535 chr2:220238732-220238733(-) m6A 3'UTR       25456834 chr2:220238849-220238850(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr2:220238858-220238859(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr2:220238889-220238890(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr2:220238915-220238916(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr2:220238998-220238999(-) m6A 3'UTR//exon       24284625//27773535 chr2:220246288-220246289(-) m6A 3'UTR//CDS//exon       - chr2:220246303-220246304(-) m6A 3'UTR//CDS//exon       - chr2:220246730-220246731(-) m6A 3'UTR//CDS//exon       27773535 chr2:220249941-220249942(-) m6A exon//intron       - chr2:220249955-220249956(-) m6A exon//intron       - chr2:220249973-220249974(-) m6A exon//intron       - chr2:220250014-220250015(-) m6A exon//intron       - chr2:220252301-220252302(-) m6A 3'UTR//intron       - chr2:220252326-220252327(-) m6A 3'UTR//intron       - chr2:220252367-220252368(-) m6A 3'UTR//intron       - chr2:220252438-220252439(-) m6A CDS//intron       24981863 chr2:220252507-220252508(-) m6A CDS//exon//intron       25456834//24981863//27371828 chr2:220252580-220252581(-) m6A 5'UTR//intron       25456834//24981863//27371828 chr2:220252659-220252660(-) m6A 5'UTR//intron       25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DNPEP	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: DNPEP

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg