Basic Information:

  VIRBase ID:  

VHID00247034

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          SETDB1:  NR_172060     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	SETDB1
miRBase Accession/Entrez ID	MIMAT0003343	9869
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ESET//H3-K9-HMTase4//KG1T//KMT1E//TDRD21

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SETDB1	chr1:150903197(+) A-I      intronic chr1:150926226(+) A-I      intronic chr1:150903526(+) A-I      intronic chr1:150903130(+) A-I      intronic chr1:150934797(+) A-I      intronic chr1:150933865(+) A-I      intronic chr1:150930845(+) A-I      intronic chr1:150934714(+) A-I      intronic chr1:150933867(+) A-I      intronic chr1:150930519(+) A-I      intronic chr1:150903129(+) A-I      intronic chr1:150903166(+) A-I      intronic chr1:150903188(+) A-I      intronic chr1:150933880(+) A-I      intronic chr1:150930492(+) A-I      intronic chr1:150930541(+) A-I      intronic chr1:150926237(+) A-I      intronic chr1:150911109(+) A-I      intronic chr1:150911035(+) A-I      intronic chr1:150910652(+) A-I      intronic chr1:150903904(+) A-I      intronic chr1:150903889(+) A-I      intronic chr1:150903884(+) A-I      intronic chr1:150906812(+) A-I      intronic chr1:150912167(+) A-I      intronic chr1:150926541(+) A-I      intronic chr1:150926285(+) A-I      intronic chr1:150925643(+) A-I      intronic chr1:150909339(+) A-I      intronic chr1:150926146(+) A-I      intronic chr1:150906828(+) A-I      intronic chr1:150906931(+) A-I      intronic chr1:150903724(+) A-I      intronic chr1:150909490(+) A-I      intronic chr1:150903550(+) A-I      intronic chr1:150929674(+) A-I      intronic chr1:150909414(+) A-I      intronic chr1:150919998(+) A-I      intronic chr1:150911145(+) A-I      intronic chr1:150926184(+) A-I      intronic chr1:150903286(+) A-I      intronic chr1:150921223(+) A-I      intronic chr1:150906014(+) A-I      intronic chr1:150926460(+) A-I      intronic chr1:150906747(+) A-I      intronic chr1:150909220(+) A-I      intronic chr1:150926244(+) A-I      intronic chr1:150909480(+) A-I      intronic chr1:150919991(+) A-I      intronic chr1:150926214(+) A-I      intronic chr1:150903571(+) A-I      intronic chr1:150929705(+) A-I      intronic chr1:150926748(+) A-I      intronic chr1:150903575(+) A-I      intronic chr1:150911966(+) A-I      intronic chr1:150907558(+) A-I      intronic chr1:150906899(+) A-I      intronic chr1:150908537(+) A-I      intronic chr1:150903255(+) A-I      intronic chr1:150906898(+) A-I      intronic chr1:150906010(+) A-I      intronic chr1:150912181(+) A-I      intronic chr1:150926250(+) A-I      intronic chr1:150906906(+) A-I      intronic chr1:150926249(+) A-I      intronic chr1:150903472(+) A-I      intronic chr1:150906019(+) A-I      intronic chr1:150920005(+) A-I      intronic chr1:150906785(+) A-I      intronic chr1:150906724(+) A-I      intronic chr1:150905745(+) A-I      intronic chr1:150903480(+) A-I      intronic chr1:150910647(+) A-I      intronic chr1:150903850(+) A-I      intronic chr1:150903828(+) A-I      intronic chr1:150903203(+) A-I      intronic chr1:150908703(+) A-I      intronic chr1:150926290(+) A-I      intronic chr1:150929671(+) A-I      intronic chr1:150906782(+) A-I      intronic chr1:150905726(+) A-I      intronic chr1:150929664(+) A-I      intronic chr1:150908519(+) A-I      intronic chr1:150911118(+) A-I      intronic chr1:150909217(+) A-I      intronic chr1:150926699(+) A-I      intronic chr1:150907559(+) A-I      intronic chr1:150903194(+) A-I      intronic chr1:150903723(+) A-I      intronic chr1:150920498(+) A-I      intronic chr1:150930854(+) A-I      intronic chr1:150929491(+) A-I      intronic chr1:150903069(+) A-I      intronic chr1:150903665(+) A-I      intronic chr1:150932315(+) A-I      intronic chr1:150903940(+) A-I      intronic chr1:150928635(+) A-I      intronic chr1:150924438(+) A-I      intronic chr1:150930624(+) A-I      intronic chr1:150910550(+) A-I      intronic chr1:150905567(+) A-I      intronic chr1:150903576(+) A-I      intronic chr1:150911421(+) A-I      intronic chr1:150903589(+) A-I      intronic chr1:150903580(+) A-I      intronic chr1:150903973(+) A-I      intronic chr1:150909522(+) A-I      intronic chr1:150919897(+) A-I      intronic chr1:150926515(+) A-I      intronic chr1:150902080(+) A-I      intronic chr1:150926472(+) A-I      intronic chr1:150929663(+) A-I      intronic chr1:150930512(+) A-I      intronic chr1:150903462(+) A-I      intronic chr1:150926678(+) A-I      intronic chr1:150930893(+) A-I      intronic chr1:150904598(+) A-I      intronic chr1:150930467(+) A-I      intronic chr1:150911589(+) A-I      intronic chr1:150933874(+) A-I      intronic chr1:150903105(+) A-I      intronic chr1:150930300(+) A-I      intronic chr1:150929526(+) A-I      intronic chr1:150909589(+) A-I      intronic chr1:150924503(+) A-I      intronic chr1:150934905(+) A-I      intronic chr1:150930430(+) A-I      intronic chr1:150915966(+) A-I      intronic chr1:150929792(+) A-I      intronic chr1:150930401(+) A-I      intronic chr1:150930297(+) A-I      intronic chr1:150911471(+) A-I      intronic chr1:150930840(+) A-I      intronic chr1:150911873(+) A-I      intronic chr1:150903497(+) A-I      intronic chr1:150930933(+) A-I      intronic chr1:150920654(+) A-I      intronic chr1:150905648(+) A-I      intronic chr1:150929750(+) A-I      intronic chr1:150909551(+) A-I      intronic chr1:150930911(+) A-I      intronic chr1:150930857(+) A-I      intronic chr1:150926537(+) A-I      intronic chr1:150903574(+) A-I      intronic chr1:150912146(+) A-I      intronic chr1:150910590(+) A-I      intronic chr1:150903655(+) A-I      intronic chr1:150903593(+) A-I      intronic chr1:150906360(+) A-I      intronic chr1:150904607(+) A-I      intronic chr1:150903308(+) A-I      intronic chr1:150903656(+) A-I      intronic chr1:150902073(+) A-I      intronic chr1:150909462(+) A-I      intronic chr1:150903554(+) A-I      intronic chr1:150909247(+) A-I      intronic chr1:150903474(+) A-I      intronic chr1:150930827(+) A-I      intronic chr1:150903577(+) A-I      intronic chr1:150903578(+) A-I      intronic chr1:150903171(+) A-I      intronic chr1:150928406(+) A-I      intronic chr1:150929429(+) A-I      intronic chr1:150919903(+) A-I      intronic chr1:150928837(+) A-I      intronic chr1:150909345(+) A-I      intronic chr1:150930259(+) A-I      intronic chr1:150900718(+) A-I      intronic chr1:150903175(+) A-I      intronic chr1:150924362(+) A-I      intronic chr1:150925825(+) A-I      intronic chr1:150919840(+) A-I      intronic chr1:150909481(+) A-I      intronic chr1:150926158(+) A-I      intronic chr1:150930867(+) A-I      intronic chr1:150903274(+) A-I      intronic chr1:150929724(+) A-I      intronic chr1:150903895(+) A-I      intronic chr1:150930389(+) A-I      intronic chr1:150911348(+) A-I      intronic chr1:150925686(+) A-I      intronic chr1:150903981(+) A-I      intronic chr1:150906459(+) A-I      intronic chr1:150915925(+) A-I      intronic chr1:150930759(+) A-I      intronic chr1:150915920(+) A-I      intronic chr1:150926185(+) A-I      intronic chr1:150904159(+) A-I      intronic chr1:150930649(+) A-I      intronic chr1:150933857(+) A-I      intronic chr1:150903530(+) A-I      intronic chr1:150925746(+) A-I      intronic chr1:150926659(+) A-I      intronic chr1:150909529(+) A-I      intronic chr1:150929723(+) A-I      intronic chr1:150930542(+) A-I      intronic chr1:150934745(+) A-I      intronic chr1:150911515(+) A-I      intronic chr1:150911242(+) A-I      intronic chr1:150905681(+) A-I      intronic chr1:150926470(+) A-I      intronic chr1:150925882(+) A-I      intronic chr1:150908672(+) A-I      intronic chr1:150909346(+) A-I      intronic chr1:150926592(+) A-I      intronic chr1:150929756(+) A-I      intronic chr1:150926709(+) A-I      intronic chr1:150903122(+) A-I      intronic chr1:150908602(+) A-I      intronic chr1:150905605(+) A-I      intronic chr1:150930638(+) A-I      intronic chr1:150903179(+) A-I      intronic chr1:150926664(+) A-I      intronic chr1:150905559(+) A-I      intronic chr1:150930429(+) A-I      intronic chr1:150930448(+) A-I      intronic chr1:150926212(+) A-I      intronic chr1:150903458(+) A-I      intronic chr1:150930319(+) A-I      intronic chr1:150906448(+) A-I      intronic chr1:150903104(+) A-I      intronic chr1:150928625(+) A-I      intronic chr1:150903273(+) A-I      intronic chr1:150906121(+) A-I      intronic chr1:150910683(+) A-I      intronic chr1:150906527(+) A-I      intronic chr1:150911384(+) A-I      intronic chr1:150930292(+) A-I      intronic chr1:150903585(+) A-I      intronic chr1:150912115(+) A-I      intronic chr1:150926762(+) A-I      intronic chr1:150926149(+) A-I      intronic chr1:150910586(+) A-I      intronic chr1:150903898(+) A-I      intronic chr1:150909231(+) A-I      intronic chr1:150903806(+) A-I      intronic chr1:150903180(+) A-I      intronic chr1:150903581(+) A-I      intronic chr1:150921378(+) A-I      intronic chr1:150925690(+) A-I      intronic chr1:150930568(+) A-I      intronic chr1:150930913(+) A-I      intronic chr1:150930574(+) A-I      intronic chr1:150904623(+) A-I      intronic chr1:150925823(+) A-I      intronic chr1:150911608(+) A-I      intronic chr1:150903481(+) A-I      intronic chr1:150930828(+) A-I      intronic chr1:150930274(+) A-I      intronic chr1:150905615(+) A-I      intronic chr1:150919992(+) A-I      intronic chr1:150905560(+) A-I      intronic chr1:150906480(+) A-I      intronic chr1:150920452(+) A-I      intronic chr1:150906115(+) A-I      intronic chr1:150909269(+) A-I      intronic chr1:150904605(+) A-I      intronic chr1:150908727(+) A-I      intronic chr1:150930831(+) A-I      intronic chr1:150911241(+) A-I      intronic chr1:150929495(+) A-I      intronic chr1:150925689(+) A-I      intronic chr1:150906359(+) A-I      intronic chr1:150930515(+) A-I      intronic chr1:150929746(+) A-I      intronic chr1:150933975(+) A-I      intronic chr1:150933873(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SETDB1	chr1:150925745(+) A-I intron -    21960545 chr1:150926664(+) A-I intron -    21960545 chr1:150903069(+) A-G intron -    22484847 chr1:150903175(+) A-G intron -    22484847 chr1:150903179(+) A-G intron -    22484847 chr1:150903273(+) A-G intron -    22484847 chr1:150903274(+) A-G intron -    22484847 chr1:150903474(+) A-G intron -    22484847 chr1:150903530(+) A-G intron -    22484847 chr1:150903577(+) A-G intron -    22484847 chr1:150903655(+) A-G intron -    22484847 chr1:150903656(+) A-G intron -    22484847 chr1:150903940(+) A-G intron -    22484847 chr1:150905559(+) A-G intron -    22484847 chr1:150905560(+) A-G intron -    22484847 chr1:150905567(+) A-G intron -    22484847 chr1:150905681(+) A-G intron -    22484847 chr1:150906111(+) T-C intron -    22484847 chr1:150906115(+) A-G intron -    22484847 chr1:150906121(+) A-G intron -    22484847 chr1:150906359(+) A-G intron -    22484847 chr1:150906360(+) A-G intron -    22484847 chr1:150906527(+) A-G intron -    22484847 chr1:150908602(+) A-G intron -    22484847 chr1:150908672(+) A-G intron -    22484847 chr1:150910550(+) A-G intron -    22484847 chr1:150910586(+) A-G intron -    22484847 chr1:150911241(+) A-G intron -    22484847 chr1:150911242(+) A-G intron -    22484847 chr1:150911471(+) A-G intron -    22484847 chr1:150919840(+) A-G intron -    22484847 chr1:150919992(+) A-G intron -    22484847 chr1:150921378(+) A-G intron -    22484847 chr1:150924362(+) A-G intron -    22484847 chr1:150926212(+) A-G intron -    22484847 chr1:150926470(+) A-G intron -    22484847 chr1:150926537(+) A-G intron -    22484847 chr1:150926664(+) A-G intron -    22484847 chr1:150926678(+) A-G intron -    22484847 chr1:150926762(+) A-G intron -    22484847 chr1:150928837(+) A-G intron -    22484847 chr1:150929510(+) T-C intron -    22484847 chr1:150929526(+) A-G intron -    22484847 chr1:150929663(+) A-G intron -    22484847 chr1:150929750(+) A-G intron -    22484847 chr1:150930287(+) T-C intron -    22484847 chr1:150930389(+) A-G intron -    22484847 chr1:150930429(+) A-G intron -    22484847 chr1:150930448(+) A-G intron -    22484847 chr1:150930512(+) A-G intron -    22484847 chr1:150930515(+) A-G intron -    22484847 chr1:150930542(+) A-G intron -    22484847 chr1:150930759(+) A-G intron -    22484847 chr1:150930827(+) A-G intron -    22484847 chr1:150930828(+) A-G intron -    22484847 chr1:150930831(+) A-G intron -    22484847 chr1:150930840(+) A-G intron -    22484847 chr1:150930854(+) A-G intron -    22484847 chr1:150930867(+) A-G intron -    22484847 chr1:150930911(+) A-G intron -    22484847 chr1:150930933(+) A-G intron -    22484847 chr1:150930955(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SETDB1	chr1:150898983-150898984(+) Am 5'UTR//intron       - chr1:150899117-150899118(+) m6A 5'UTR//intron       - chr1:150900285-150900286(+) m6A CDS//exon       24981863 chr1:150900306-150900307(+) m6A CDS//exon       24981863 chr1:150900330-150900331(+) m6A CDS//exon       24981863 chr1:150900385-150900386(+) m6A CDS//exon       - chr1:150902474-150902475(+) m6A CDS//exon       22608085 chr1:150902493-150902494(+) m6A CDS//exon       22608085 chr1:150902507-150902508(+) m6A CDS//exon       22608085 chr1:150902628-150902629(+) m6A exon//intron       22608085 chr1:150902640-150902641(+) m6A exon//intron       24209618//22608085 chr1:150902684-150902685(+) m6A exon//intron       24209618//22608085 chr1:150917509-150917510(+) m6A 3'UTR//CDS//intron       24284625 chr1:150917632-150917633(+) m6A CDS//intron       24284625 chr1:150919472-150919473(+) m6A CDS//intron       24284625 chr1:150921656-150921657(+) m6A CDS//intron       24284625 chr1:150921676-150921677(+) m6A CDS//intron       24284625 chr1:150921977-150921978(+) m6A CDS//intron       24284625//24981863 chr1:150921993-150921994(+) m6A CDS//intron       24284625//24981863 chr1:150923113-150923114(+) m6A CDS//intron       24284625//24981863//22575960//22608085 chr1:150923145-150923146(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085 chr1:150923237-150923238(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150923261-150923262(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150923294-150923295(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150923352-150923353(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150923394-150923395(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150923562-150923563(+) m6A CDS//intron       24284625//22575960//22608085 chr1:150923933-150923934(+) m6A CDS//intron       24284625 chr1:150933065-150933066(+) m6A CDS//exon       24284625//24981863//22608085 chr1:150933110-150933111(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:150933131-150933132(+) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085 chr1:150933188-150933189(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933197-150933198(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933227-150933228(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933281-150933282(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933328-150933329(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933351-150933352(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933361-150933362(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933374-150933375(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933396-150933397(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933463-150933464(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933473-150933474(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933553-150933554(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:150933621-150933622(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr1:150933644-150933645(+) m6A CDS       24284625//25456834//24981863//27773535//22575960//22608085 chr1:150933651-150933652(+) m6A CDS       24284625//25456834//24981863//27773535//22575960//22608085 chr1:150933835-150933836(+) m6A exon//intron       24284625//25456834//24981863//27773535//22608085 chr1:150935164-150935165(+) m6A CDS//exon       27773535 chr1:150935373-150935374(+) m6A exon//intron       27773535 chr1:150935392-150935393(+) m6A exon//intron       27773535 chr1:150935497-150935498(+) m6A CDS//exon       27773535 chr1:150936104-150936105(+) m6A CDS//exon       - chr1:150936134-150936135(+) m6A CDS//exon       - chr1:150936309-150936310(+) m6A CDS//exon//intron       27773535 chr1:150936843-150936844(+) m6A 3'UTR//exon       24981863 chr1:150936869-150936870(+) m6A 3'UTR//exon       24284625//24981863 chr1:150936887-150936888(+) m6A 3'UTR//exon       24284625 chr1:150936909-150936910(+) m6A 3'UTR//exon       24284625 chr1:150936977-150936978(+) m6A 3'UTR//exon       24284625 chr1:150937126-150937127(+) m6A 3'UTR//exon       27773535 chr1:150937208-150937209(+) m6A 3'UTR//exon       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SETDB1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: SETDB1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg