Basic Information:

  VIRBase ID:  

VHID00246346

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          SUMO3:  NM_006936     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	SUMO3
miRBase Accession/Entrez ID	MIMAT0003343	6612
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SMT3A//Smt3B//SMT3H1//SUMO-3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SUMO3	chr21:46228328(-) A-I      Syn:Ser->Ser chr21:46232087(-) A-I      intronic chr21:46232100(-) A-I      intronic chr21:46231392(-) A-I      intronic chr21:46231473(-) A-I      intronic chr21:46232096(-) A-I      intronic chr21:46232213(-) A-I      intronic chr21:46232176(-) A-I      intronic chr21:46231306(-) A-I      intronic chr21:46232172(-) A-I      intronic chr21:46231330(-) A-I      intronic chr21:46231375(-) A-I      intronic chr21:46231460(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SUMO3	chr21:46226204-46226205(-) m6A 3'UTR//exon       - chr21:46226713-46226714(-) m6A 3'UTR//exon       24981863//27773535 chr21:46226766-46226767(-) m6A 3'UTR//exon       24981863//27371828//27773536 chr21:46226774-46226775(-) m6A 3'UTR//exon       24981863//27371828//27773536 chr21:46226935-46226936(-) m6A CDS//exon       24209618//27773535//27371828//27773536//22575960 chr21:46228308-46228309(-) m6A CDS//intron       - chr21:46228978-46228979(-) m6A CDS//exon       27773535//27371828//27773536//22575960 chr21:46233465-46233466(-) m6A exon//intron       27773535//27371828//27773536//22575960 chr21:46233946-46233947(-) Am CDS//exon       - chr21:46234006-46234007(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SUMO3	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: SUMO3

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg