Detail Information

Basic Information:


  VIRBase ID:  

VHID00246303

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:           SHC1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-UL70-3p SHC1
miRBase
Accession/Entrez ID		 MIMAT0003343 6464
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - SHC//SHCA

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SHC1
chr1:154936769(-) A-I      NonSyn:Arg->Gly
chr1:154945824(-) A-I      intronic
chr1:154945924(-) A-I      intronic
chr1:154945948(-) A-I      intronic
chr1:154936829(-) A-I      NonSyn:Met->Val
chr1:154936807(-) A-I      NonSyn:Asn->Ser
chr1:154936820(-) A-I      NonSyn:Lys->Glu
chr1:154936794(-) A-I      Syn:Gln->Gln
chr1:154936819(-) A-I      NonSyn:Lys->Arg
chr1:154936755(-) A-I      Syn:Leu->Leu
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SHC1
chr1:154936819(-) A-I intron -    22327324
chr1:154937223(-) A-I intron -    21960545
chr1:154934788(-) T-C exon 3'UTR    21725310
chr1:154936755(-) A-G intron -    22484847
chr1:154936819(-) A-G intron -    22484847
chr1:154937141(-) A-G intron -    22484847
chr1:154937169(-) A-G intron -    22484847
chr1:154937197(-) A-G intron -    22484847
chr1:154937208(-) A-G intron -    22484847
chr1:154937223(-) A-G intron -    22484847
chr1:154937237(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SHC1
chr1:154934801-154934802(-) m6A 3'UTR       24284625//27773535//22608085
chr1:154934981-154934982(-) m6A 3'UTR       24284625//24981863//26404942//22575960//22608085
chr1:154935038-154935039(-) m6A 3'UTR       24981863//26404942//22575960//22608085
chr1:154935059-154935060(-) m6A 3'UTR       24981863//26404942//22608085
chr1:154935068-154935069(-) m6A 3'UTR       24981863//26404942//22608085
chr1:154935101-154935102(-) m6A 3'UTR       24981863
chr1:154935269-154935270(-) m6A 3'UTR       27773535
chr1:154935315-154935316(-) m6A 3'UTR       27773535
chr1:154935346-154935347(-) m6A 3'UTR       27773535
chr1:154935361-154935362(-) m6A 3'UTR       27773535
chr1:154935609-154935610(-) m6A 3'UTR       24284625
chr1:154935853-154935854(-) m6A 3'UTR//exon       24284625//27773535
chr1:154935886-154935887(-) m6A 3'UTR//exon       24284625//27773535
chr1:154935920-154935921(-) m6A 3'UTR//exon       24284625//27773535
chr1:154935946-154935947(-) m6A 3'UTR//exon       24284625//27773535
chr1:154936078-154936079(-) m6A 3'UTR//exon       24284625//24981863//26404942
chr1:154936152-154936153(-) m6A 3'UTR//exon       24284625//24981863//26404942
chr1:154936210-154936211(-) m6A 3'UTR//exon       24284625//25456834//24981863//22575960//22608085
chr1:154936284-154936285(-) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27773535//22575960//22608085
chr1:154936314-154936315(-) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27773535//22575960//22608085
chr1:154936348-154936349(-) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27773535//22575960//22608085
chr1:154936400-154936401(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22575960
chr1:154938435-154938436(-) m6A CDS       24284625
chr1:154938504-154938505(-) m6A CDS       24284625//27773535
chr1:154938510-154938511(-) m6A CDS       24284625//27773535
chr1:154938665-154938666(-) m6A CDS       24284625//27773535
chr1:154938698-154938699(-) m6A CDS       24284625//27773535
chr1:154938820-154938821(-) m6A CDS       24284625//27773535
chr1:154938882-154938883(-) m6A CDS       24284625//27773535//22575960
chr1:154938905-154938906(-) m6A CDS       24284625//27773535//22575960
chr1:154940166-154940167(-) m6A CDS       24284625//27773535//22575960
chr1:154940176-154940177(-) m6A CDS       24284625//27773535//22575960
chr1:154940190-154940191(-) m6A CDS       24284625//27773535
chr1:154940472-154940473(-) m6A CDS       27773535
chr1:154940973-154940974(-) m6A CDS       24284625//27773535
chr1:154940980-154940981(-) m6A CDS       24284625//27773535
chr1:154941866-154941867(-) m6A CDS//intron       24284625//24209618//27773535
chr1:154941880-154941881(-) m6A CDS//intron       24284625//24209618//27773535
chr1:154942531-154942532(-) m6A CDS//intron       24284625//24209618//25456834//27371828//22575960
chr1:154942599-154942600(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr1:154942638-154942639(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960
chr1:154942667-154942668(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960
chr1:154942673-154942674(-) m6A 5'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960
chr1:154942700-154942701(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960
chr1:154943049-154943050(-) m6A 5'UTR//intron       24284625//24209618//24981863//22575960
chr1:154943128-154943129(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960
chr1:154943183-154943184(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960
chr1:154945781-154945782(-) m6A 5'UTR//intron       24284625//25456834//24981863
chr1:154946738-154946739(-) m6A 5'UTR       24284625//24209618//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate SHC1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-UL70-3p
l-685,458       5479543
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-UL70-3p
Interactor2: SHC1

Evidence Support:


Prediction-Evidence miRanda//RNAHybrid
Support Database VmiReg

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