Detail Information

Basic Information:


  VIRBase ID:  

VHID00246112

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:           PPP1R8:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-UL70-3p PPP1R8
miRBase
Accession/Entrez ID		 MIMAT0003343 5511
Organism Human betaherpesvirus 5 (HHV-5) Homo sapiens
Category miRNA mRNA
Alias - ARD-1//ARD1//NIPP-1//NIPP1//PRO2047

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PPP1R8
chr1:28170349(+) A-I      intronic
chr1:28170343(+) A-I      intronic
chr1:28170591(+) A-I      intronic
chr1:28170337(+) A-I      intronic
chr1:28170333(+) A-I      intronic
chr1:28170325(+) A-I      intronic
chr1:28170317(+) A-I      intronic
chr1:28170299(+) A-I      intronic
chr1:28169904(+) A-I      intronic
chr1:28164816(+) A-I      intronic
chr1:28164568(+) A-I      intronic
chr1:28175721(+) A-I      intronic
chr1:28175724(+) A-I      intronic
chr1:28164565(+) A-I      intronic
chr1:28163862(+) A-I      intronic
chr1:28175723(+) A-I      intronic
chr1:28163136(+) A-I      intronic
chr1:28163067(+) A-I      intronic
chr1:28163065(+) A-I      intronic
chr1:28175727(+) A-I      intronic
chr1:28163006(+) A-I      intronic
chr1:28175668(+) A-I      intronic
chr1:28172515(+) A-I      intronic
chr1:28172486(+) A-I      intronic
chr1:28171370(+) A-I      intronic
chr1:28171368(+) A-I      intronic
chr1:28176069(+) A-I      intronic
chr1:28176141(+) A-I      intronic
chr1:28176183(+) A-I      intronic
chr1:28176220(+) A-I      intronic
chr1:28170978(+) A-I      intronic
chr1:28170939(+) A-I      intronic
chr1:28170779(+) A-I      intronic
chr1:28171358(+) A-I      intronic
chr1:28170577(+) A-I      intronic
chr1:28175718(+) A-I      intronic
chr1:28170383(+) A-I      intronic
chr1:28170357(+) A-I      intronic
chr1:28170308(+) A-I      intronic
chr1:28169921(+) A-I      intronic
chr1:28171355(+) A-I      intronic
chr1:28170146(+) A-I      intronic
chr1:28170313(+) A-I      intronic
chr1:28161504(+) A-I      intronic
chr1:28169985(+) A-I      intronic
chr1:28176180(+) A-I      intronic
chr1:28176077(+) A-I      intronic
chr1:28170321(+) A-I      intronic
chr1:28176139(+) A-I      intronic
chr1:28176129(+) A-I      intronic
chr1:28161512(+) A-I      intronic
chr1:28161342(+) A-I      intronic
chr1:28161409(+) A-I      intronic
chr1:28170278(+) A-I      intronic
chr1:28170652(+) A-I      intronic
chr1:28170361(+) A-I      intronic
chr1:28176063(+) A-I      intronic
chr1:28176039(+) A-I      intronic
chr1:28170335(+) A-I      intronic
chr1:28175696(+) A-I      intronic
chr1:28163665(+) A-I      intronic
chr1:28164770(+) A-I      intronic
chr1:28170232(+) A-I      intronic
chr1:28171520(+) A-I      intronic
chr1:28170562(+) A-I      intronic
chr1:28170489(+) A-I      intronic
chr1:28172508(+) A-I      intronic
chr1:28168253(+) A-I      intronic
chr1:28163279(+) A-I      intronic
chr1:28164643(+) A-I      intronic
chr1:28163287(+) A-I      intronic
chr1:28169912(+) A-I      intronic
chr1:28170106(+) A-I      intronic
chr1:28170206(+) A-I      intronic
chr1:28164776(+) A-I      intronic
chr1:28176117(+) A-I      intronic
chr1:28170306(+) A-I      intronic
chr1:28163288(+) A-I      intronic
chr1:28166483(+) A-I      intronic
chr1:28164346(+) A-I      intronic
chr1:28163897(+) A-I      intronic
chr1:28161370(+) A-I      intronic
chr1:28170788(+) A-I      intronic
chr1:28170653(+) A-I      intronic
chr1:28175697(+) A-I      intronic
chr1:28170072(+) A-I      intronic
chr1:28171100(+) A-I      intronic
chr1:28164166(+) A-I      intronic
chr1:28162950(+) A-I      intronic
chr1:28171885(+) A-I      intronic
chr1:28172575(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PPP1R8
chr1:28161342(+) A-G intron -    22484847
chr1:28162950(+) A-G intron -    22484847
chr1:28163287(+) A-G intron -    22484847
chr1:28163288(+) A-G intron -    22484847
chr1:28170361(+) A-G intron -    22484847
chr1:28170788(+) A-G intron -    22484847
chr1:28175696(+) A-G intron -    22484847
chr1:28175697(+) A-G intron -    22484847
chr1:28175843(+) T-C intron -    22484847
chr1:28176063(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PPP1R8
chr1:28157362-28157363(+) m6A 5'UTR//CDS       24981863//22608085
chr1:28157372-28157373(+) Y 5'UTR//CDS       26075521
chr1:28157566-28157567(+) m6A 5'UTR//intron       24284625
chr1:28157594-28157595(+) m6A 5'UTR//intron       24284625
chr1:28157603-28157604(+) m6A 5'UTR//intron       24284625
chr1:28157692-28157693(+) m6A 5'UTR//intron       24284625
chr1:28167699-28167700(+) m6A CDS//intron       27773535
chr1:28167733-28167734(+) m6A CDS//intron       24981863//27773535
chr1:28169766-28169767(+) m6A 5'UTR//CDS       24209618//24981863//27773535
chr1:28169776-28169777(+) m6A 5'UTR//CDS       24209618//24981863//27773535
chr1:28169796-28169797(+) m6A 5'UTR//CDS       24209618//24981863//27773535
chr1:28173571-28173572(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//22608085
chr1:28173582-28173583(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr1:28176667-28176668(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr1:28176669-28176670(+) Y CDS//exon       26075521
chr1:28176686-28176687(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr1:28176750-28176751(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr1:28176787-28176788(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28176805-28176806(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28176835-28176836(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28176841-28176842(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28176853-28176854(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28176887-28176888(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr1:28177025-28177026(+) m6A 3'UTR//intron       24981863//27773535
chr1:28177038-28177039(+) m6A 3'UTR//intron       24981863//27773535
chr1:28177134-28177135(+) m6A 3'UTR//intron       27773535
chr1:28177879-28177880(+) m6A 3'UTR//intron       27773535
chr1:28177884-28177885(+) m6A 3'UTR//intron       27773535
chr1:28177897-28177898(+) m6A 3'UTR//intron       27773535
chr1:28177906-28177907(+) m6A 3'UTR//intron       27773535
chr1:28177919-28177920(+) m6A 3'UTR//intron       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate PPP1R8
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hcmv-miR-UL70-3p
l-685,458       5479543
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-UL70-3p
Interactor2: PPP1R8

Evidence Support:


Prediction-Evidence cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database RepTar//VmiReg

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