Basic Information:

  VIRBase ID:  

VHID00245854

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL70-3p:  MIMAT0003343          MLLT6:  NM_005937     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL70-3p	MLLT6
miRBase Accession/Entrez ID	MIMAT0003343	4302
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AF17

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MLLT6	chr17:36880358(+) A-I      intronic chr17:36880026(+) A-I      intronic chr17:36880014(+) A-I      intronic chr17:36879708(+) A-I      intronic chr17:36879634(+) A-I      intronic chr17:36879647(+) A-I      intronic chr17:36880434(+) A-I      intronic chr17:36880421(+) A-I      intronic chr17:36880057(+) A-I      intronic chr17:36880359(+) A-I      intronic chr17:36880113(+) A-I      intronic chr17:36880076(+) A-I      intronic chr17:36880052(+) A-I      intronic chr17:36880429(+) A-I      intronic chr17:36880390(+) A-I      intronic chr17:36879651(+) A-I      intronic chr17:36880354(+) A-I      intronic chr17:36880496(+) A-I      intronic chr17:36880360(+) A-I      intronic chr17:36880398(+) A-I      intronic chr17:36879730(+) A-I      intronic chr17:36879657(+) A-I      intronic chr17:36880357(+) A-I      intronic chr17:36880231(+) A-I      intronic chr17:36880062(+) A-I      intronic chr17:36879727(+) A-I      intronic chr17:36880135(+) A-I      intronic chr17:36879665(+) A-I      intronic chr17:36880461(+) A-I      intronic chr17:36879501(+) A-I      intronic chr17:36880430(+) A-I      intronic chr17:36880363(+) A-I      intronic chr17:36880095(+) A-I      intronic chr17:36880018(+) A-I      intronic chr17:36879624(+) A-I      intronic chr17:36880458(+) A-I      intronic chr17:36880497(+) A-I      intronic chr17:36879616(+) A-I      intronic chr17:36880096(+) A-I      intronic chr17:36879729(+) A-I      intronic chr17:36879528(+) A-I      intronic chr17:36879666(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MLLT6	chr17:36879665(+) A-G intron -    22484847 chr17:36880354(+) A-G intron -    22484847 chr17:36884054(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MLLT6	chr17:36861943-36861944(+) m6A CDS//exon       24209618 chr17:36862916-36862917(+) m1A exon//intron       26863410//26863196 chr17:36862926-36862927(+) m6A exon//intron       24209618 chr17:36863233-36863234(+) m6A CDS//exon       22575960 chr17:36863780-36863781(+) m6A CDS//exon       - chr17:36865425-36865426(+) m6A CDS//exon       24209618 chr17:36865781-36865782(+) m6A CDS//exon       24209618 chr17:36868102-36868103(+) m6A CDS//exon       24209618//22575960 chr17:36868264-36868265(+) m1A CDS//exon       26863196 chr17:36868953-36868954(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27371828 chr17:36870986-36870987(+) m6A 3'UTR//intron       - chr17:36871915-36871916(+) m6A CDS//exon       - chr17:36871986-36871987(+) m6A CDS//exon       24284625 chr17:36872151-36872152(+) m6A exon//intron       24284625 chr17:36872478-36872479(+) m6A exon//intron       24284625 chr17:36872484-36872485(+) m6A exon//intron       24284625 chr17:36872501-36872502(+) m6A exon//intron       24284625 chr17:36872508-36872509(+) m6A exon//intron       24284625 chr17:36872529-36872530(+) m6A exon//intron       24284625 chr17:36872682-36872683(+) m6A CDS       24284625//24981863 chr17:36872859-36872860(+) m6A CDS       - chr17:36872954-36872955(+) m6A CDS       25456834 chr17:36872963-36872964(+) m6A CDS       25456834 chr17:36873039-36873040(+) m6A CDS       25456834 chr17:36874151-36874152(+) m6A CDS//exon       24981863 chr17:36874252-36874253(+) m6A exon//intron       - chr17:36875775-36875776(+) m6A CDS//exon       24284625 chr17:36875784-36875785(+) m6A CDS//exon       24284625 chr17:36875807-36875808(+) m6A CDS//exon       24284625 chr17:36876039-36876040(+) m6A CDS//exon       24284625 chr17:36876073-36876074(+) m6A CDS//exon       24284625 chr17:36876666-36876667(+) m6A CDS//exon       24284625 chr17:36876974-36876975(+) m6A CDS//exon       24284625 chr17:36877038-36877039(+) m6A CDS//intron       24284625 chr17:36878948-36878949(+) m6A CDS//exon       24284625 chr17:36880534-36880535(+) m6A exon//intron       24284625 chr17:36880874-36880875(+) m6A CDS//exon       - chr17:36880881-36880882(+) m6A CDS//exon       - chr17:36881147-36881148(+) m6A CDS//exon       24284625 chr17:36881169-36881170(+) m6A CDS//exon       24284625 chr17:36881809-36881810(+) m6A CDS//exon       - chr17:36881890-36881891(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr17:36881940-36881941(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr17:36882009-36882010(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr17:36882015-36882016(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr17:36882089-36882090(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr17:36882189-36882190(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr17:36882289-36882290(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960 chr17:36882338-36882339(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863 chr17:36882347-36882348(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863 chr17:36882556-36882557(+) m6A 3'UTR//exon//intron       24284625//24209618//22575960 chr17:36882681-36882682(+) m6A 3'UTR//exon//intron       24284625//24209618 chr17:36882743-36882744(+) m6A 3'UTR//exon//intron       24284625//24209618 chr17:36882818-36882819(+) m6A 3'UTR//exon//intron       24284625 chr17:36884853-36884854(+) m6A 3'UTR       24209618 chr17:36884939-36884940(+) m6A 3'UTR       24981863 chr17:36884952-36884953(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MLLT6	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL70-3p	l-685,458       5479543 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL70-3p
Interactor2: MLLT6

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg